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Protein
Submitted name:

Vacuolar protein sorting-associated protein 54

Gene

Vps54

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Vacuolar protein sorting-associated protein 54Imported
Gene namesi
Name:Vps54Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:2178798 Vps54

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiQ5SRW8
PRIDEiQ5SRW8

Expressioni

Gene expression databases

BgeeiENSMUSG00000020128 Expressed in 288 organ(s), highest expression level in cumulus cell
ExpressionAtlasiQ5SRW8 baseline and differential

Structurei

3D structure databases

SMRiQ5SRW8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini81 – 229Vps54_NInterPro annotationAdd BLAST149
Domaini575 – 704Vps54InterPro annotationAdd BLAST130

Phylogenomic databases

eggNOGiKOG2115 Eukaryota
ENOG410XQ3K LUCA
GeneTreeiENSGT00390000000583
HOGENOMiHOG000045110
HOVERGENiHBG068681

Family and domain databases

InterProiView protein in InterPro
IPR039745 Vps54
IPR012501 Vps54_C
IPR019515 VPS54_N
PANTHERiPTHR12965 PTHR12965, 2 hits
PfamiView protein in Pfam
PF07928 Vps54, 1 hit
PF10475 Vps54_N, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5SRW8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
REKIHERCKN ICPPKDTFDR TLLHIHDKSR TDLEQVPKIF MKPDFALDDS
60 70 80 90 100
LTFNSVLPWS HFNTAGGKGS RDAASSKLLQ EKLSHYLDIV EVNIAHQISL
110 120 130 140 150
RSEAFFHAMT SQHELQDYLK KTTQAVKMLR DKIAQIDKVM CEGSLQILRL
160 170 180 190 200
ALTRNNCVKV YNKLKLMATV HQTQPTVQVL LSTSEFVGAL DLIATTQEVL
210 220 230 240 250
QQELQGIHSF RHLGSQLCEL EKLIDKMMIA EFSTYSHSDL NRPLEGECQV
260 270 280 290 300
LEERVINKVS QIEEIDTDVV VKLADQMRML NFPQWIDLLK DIFSKFTVFL
310 320 330 340 350
QRVKATLNII HSVVLSVLEK SQRTRELEEI PQQRSAGKDS SLDTDVAYLT
360 370 380 390 400
HEGWFISDAF SEGEPASAAV DTTSQRNTSP HSEPCSSDSV SEPECTTDSS
410 420 430 440 450
SSKEQTSACA PPGGIEIIVS EDMRLTDLEL GKLASNIQEL LCNASDVCHD
460 470 480 490 500
RAVKFLMSRA KDGFLEKLNS TEFIALSRLM ETFIVDTEQI CGRKSTSLLG
510 520 530 540 550
ALQSQANKFV NRFHEERRTK LSLLLDNERW KQADVPAEFQ DLVDSIADGK
560 570 580 590 600
IALPEKKPVV TEERKPADVL VVEGHQYAVV GTVLLLIRII LEYCQCVDNI
610 620 630 640 650
PSVTTDMLTR LTDLLKYFNS RSCQLVLGAG ALQVVGLKTI TTKNLALSSR
660 670 680 690 700
CLQLIVHYIP VIRAHFEARL PPKQWSMLRH FDHITKDYHD HIAEISAKLV
710 720 730 740 750
AIMDSLFDKL LSKYEVKAPV PSPCFRNICK QMTKMHEAIF DLLPEEQTQM
760 770 780 790 800
LFLRINASYK LHLKKQLSHL NVINDGGPQN GLVTADVAFY TGNLQALKGL
810
KDLDLNMAEI WEQKR
Length:815
Mass (Da):92,112
Last modified:February 5, 2008 - v1
Checksum:i4A4DC4E4B254EBD1
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5SPW0VPS54_MOUSE
Vacuolar protein sorting-associated...
Vps54
977Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL669979 Genomic DNA No translation available.
AL833772 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000132017; ENSMUSP00000116739; ENSMUSG00000020128

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL669979 Genomic DNA No translation available.
AL833772 Genomic DNA No translation available.

3D structure databases

SMRiQ5SRW8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiQ5SRW8
PRIDEiQ5SRW8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000132017; ENSMUSP00000116739; ENSMUSG00000020128

Organism-specific databases

MGIiMGI:2178798 Vps54

Phylogenomic databases

eggNOGiKOG2115 Eukaryota
ENOG410XQ3K LUCA
GeneTreeiENSGT00390000000583
HOGENOMiHOG000045110
HOVERGENiHBG068681

Miscellaneous databases

ChiTaRSiVps54 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020128 Expressed in 288 organ(s), highest expression level in cumulus cell
ExpressionAtlasiQ5SRW8 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR039745 Vps54
IPR012501 Vps54_C
IPR019515 VPS54_N
PANTHERiPTHR12965 PTHR12965, 2 hits
PfamiView protein in Pfam
PF07928 Vps54, 1 hit
PF10475 Vps54_N, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5SRW8_MOUSE
AccessioniPrimary (citable) accession number: Q5SRW8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: November 7, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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