UniProtKB - Q5SRL0 (Q5SRL0_HUMAN)
Protein
Submitted name:
TRIM15
Gene
TRIM15
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- zinc ion binding Source: InterPro
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: TRIM15ImportedSubmitted name: Tripartite motif-containing 15ImportedSubmitted name: cDNA FLJ75016, highly similar to Homo sapiens tripartite motif-containing 15 (TRIM15), transcript variant 1, mRNAImported |
Gene namesi | Name:TRIM15Imported ORF Names:hCG_23773Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000204610.12 |
Expressioni
Gene expression databases
Bgeei | ENSG00000204610, Expressed in duodenum and 100 other tissues |
ExpressionAtlasi | Q5SRL0, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 61 | RING-typeInterPro annotationAdd BLAST | 46 | |
Domaini | 78 – 119 | B box-typeInterPro annotationAdd BLAST | 42 | |
Domaini | 276 – 465 | B30.2/SPRYInterPro annotationAdd BLAST | 190 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 127 – 147 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 159 – 186 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 206 – 226 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
HOGENOMi | CLU_013137_0_3_1 |
OMAi | CWASTCP |
OrthoDBi | 423686at2759 |
Family and domain databases
Gene3Di | 2.60.120.920, 1 hit 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR001870, B30.2/SPRY IPR043136, B30.2/SPRY_sf IPR003879, Butyrophylin_SPRY IPR013320, ConA-like_dom_sf IPR006574, PRY IPR003877, SPRY_dom IPR000315, Znf_B-box IPR018957, Znf_C3HC4_RING-type IPR001841, Znf_RING IPR013083, Znf_RING/FYVE/PHD IPR017907, Znf_RING_CS |
Pfami | View protein in Pfam PF13765, PRY, 1 hit PF00622, SPRY, 1 hit PF00643, zf-B_box, 1 hit PF00097, zf-C3HC4, 1 hit |
PRINTSi | PR01407, BUTYPHLNCDUF |
SMARTi | View protein in SMART SM00336, BBOX, 1 hit SM00589, PRY, 1 hit SM00184, RING, 1 hit SM00449, SPRY, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit |
PROSITEi | View protein in PROSITE PS50188, B302_SPRY, 1 hit PS50119, ZF_BBOX, 1 hit PS00518, ZF_RING_1, 1 hit PS50089, ZF_RING_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5SRL0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPATPSLKVV HELPACTLCA GPLEDAVTIP CGHTFCRLCL PALSQMGAQS
60 70 80 90 100
SGKILLCPLC QEEEQAETPM APVPLGPLGE TYCEEHGEKI YFFCENDAEF
110 120 130 140 150
LCVFCREGPT HQAHTVGFLD EAIQPYRDRL RSRLEALSTE RDEIEDVKCQ
160 170 180 190 200
EDQKLQVLLT QIESKKHQVE TAFERLQQEL EQQRCLLLAR LRELEQQIWK
210 220 230 240 250
ERDEYITKVS EEVTRLGAQV KELEEKCQQP ASELLQDVRV NQSRCEMKTF
260 270 280 290 300
VSPEAISPDL VKKIRDFHRK ILTLPEMMRM FSENLAHHLE IDSGVITLDP
310 320 330 340 350
QTASRSLVLS EDRKSVRYTR QKKSLPDSPL RFDGLPAVLG FPGFSSGRHR
360 370 380 390 400
WQVDLQLGDG GGCTVGVAGE GVRRKGEMGL SAEDGVWAVI ISHQQCWAST
410 420 430 440 450
SPGTDLPLSE IPRGVRVALD YEAGQVTLHN AQTQEPIFTF TASFSGKVFP
460
FFAVWKKGSC LTLKG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | KY500683 Genomic DNA Translation: AQY77155.1 KY500685 Genomic DNA Translation: AQY77157.1 KY500687 Genomic DNA Translation: AQY77159.1 AB202085 Genomic DNA Translation: BAE78606.1 AK291853 mRNA Translation: BAF84542.1 CH471081 Genomic DNA Translation: EAX03271.1 |
RefSeqi | NP_150232.2, NM_033229.2 |
Genome annotation databases
GeneIDi | 89870 |
KEGGi | hsa:89870 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | KY500683 Genomic DNA Translation: AQY77155.1 KY500685 Genomic DNA Translation: AQY77157.1 KY500687 Genomic DNA Translation: AQY77159.1 AB202085 Genomic DNA Translation: BAE78606.1 AK291853 mRNA Translation: BAF84542.1 CH471081 Genomic DNA Translation: EAX03271.1 |
RefSeqi | NP_150232.2, NM_033229.2 |
3D structure databases
SMRi | Q5SRL0 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 26243, 173 antibodies |
DNASUi | 89870 |
Genome annotation databases
GeneIDi | 89870 |
KEGGi | hsa:89870 |
Organism-specific databases
CTDi | 89870 |
PharmGKBi | PA38114 |
VEuPathDBi | HostDB:ENSG00000204610.12 |
Phylogenomic databases
HOGENOMi | CLU_013137_0_3_1 |
OMAi | CWASTCP |
OrthoDBi | 423686at2759 |
Miscellaneous databases
BioGRID-ORCSi | 89870, 5 hits in 984 CRISPR screens |
ChiTaRSi | TRIM15, human |
GenomeRNAii | 89870 |
Gene expression databases
Bgeei | ENSG00000204610, Expressed in duodenum and 100 other tissues |
ExpressionAtlasi | Q5SRL0, baseline and differential |
Family and domain databases
Gene3Di | 2.60.120.920, 1 hit 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR001870, B30.2/SPRY IPR043136, B30.2/SPRY_sf IPR003879, Butyrophylin_SPRY IPR013320, ConA-like_dom_sf IPR006574, PRY IPR003877, SPRY_dom IPR000315, Znf_B-box IPR018957, Znf_C3HC4_RING-type IPR001841, Znf_RING IPR013083, Znf_RING/FYVE/PHD IPR017907, Znf_RING_CS |
Pfami | View protein in Pfam PF13765, PRY, 1 hit PF00622, SPRY, 1 hit PF00643, zf-B_box, 1 hit PF00097, zf-C3HC4, 1 hit |
PRINTSi | PR01407, BUTYPHLNCDUF |
SMARTi | View protein in SMART SM00336, BBOX, 1 hit SM00589, PRY, 1 hit SM00184, RING, 1 hit SM00449, SPRY, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit |
PROSITEi | View protein in PROSITE PS50188, B302_SPRY, 1 hit PS50119, ZF_BBOX, 1 hit PS00518, ZF_RING_1, 1 hit PS50089, ZF_RING_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5SRL0_HUMAN | |
Accessioni | Q5SRL0Primary (citable) accession number: Q5SRL0 Secondary accession number(s): A6NEF7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | April 7, 2021 | |
This is version 168 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |