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Protein
Submitted name:

Neuroepithelial cell transforming gene 1, isoform CRA_a

Gene

NET1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Neuroepithelial cell transforming gene 1, isoform CRA_aImported
Submitted name:
cDNA, FLJ96638, Homo sapiens neuroepithelial cell transforming gene 1 (NET1), mRNAImported
Gene namesi
Name:NET1Imported
ORF Names:hCG_19072Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000173848.18

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSG00000173848 Expressed in 237 organ(s), highest expression level in tendon

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini120 – 302DHInterPro annotationAdd BLAST183
Domaini332 – 447PHInterPro annotationAdd BLAST116

Phylogenomic databases

eggNOGiKOG4305 Eukaryota
COG5422 LUCA
HOGENOMiHOG000034044
HOVERGENiHBG050567

Family and domain databases

CDDicd13224 PH_Net1, 1 hit
cd00160 RhoGEF, 1 hit
Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR001331 GDS_CDC24_CS
IPR037853 Net1_PH
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00621 RhoGEF, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00325 RhoGEF, 1 hit
SUPFAMiSSF48065 SSF48065, 1 hit
PROSITEiView protein in PROSITE
PS00741 DH_1, 1 hit
PS50010 DH_2, 1 hit
PS50003 PH_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q5SQI7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVAHDETGGL LPIKRTIRVL DVNNQSFREQ EEPSNKRVRP LARVTSLANL
60 70 80 90 100
ISPVRNGAVR RFGQTIQSFT LRGDHRSPAS AQKFSSRSTV PTPAKRRSSA
110 120 130 140 150
LWSEMLDITM KESLTTREIR RQEAIYEMSR GEQDLIEDLK LARKAYHDPM
160 170 180 190 200
LKLSIMSEEE LTHIFGDLDS YIPLHEDLLT RIGEATKPDG TVEQIGHILV
210 220 230 240 250
SWLPRLNAYR GYCSNQLAAK ALLDQKKQDP RVQDFLQRCL ESPFSRKLDL
260 270 280 290 300
WSFLDIPRSR LVKYPLLLKE ILKHTPKEHP DVQLLEDAIL IIQGVLSDIN
310 320 330 340 350
LKKGESECQY YIDKLEYLDE KQRDPRIEAS KVLLCHGELR SKSGHKLYIF
360 370 380 390 400
LFQDILVLTR PVTRNERHSY QVYRQPIPVQ ELVLEDLQDG DVRMGGSFRG
410 420 430 440 450
AFSNSEKAKN IFRIRFHDPS PAQSHTLQAN DVFHKQQWFN CIRAAIAPFQ
460 470 480 490 500
SAGSPPELQG LPELHEECEG NHPSARKLTA QRRASTVSSV TQVEVDENAY
510 520 530 540
RCGSGMQMAE DSKSLKTHQT QPGIRRARDK ALSGGKRKET LV
Length:542
Mass (Da):61,885
Last modified:May 10, 2005 - v1
Checksum:i770F252F0FCA7E92
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK315566 mRNA Translation: BAG37941.1
CH471072 Genomic DNA Translation: EAW86445.1
RefSeqiNP_005854.2, NM_005863.4
UniGeneiHs.25155

Genome annotation databases

GeneIDi10276

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK315566 mRNA Translation: BAG37941.1
CH471072 Genomic DNA Translation: EAW86445.1
RefSeqiNP_005854.2, NM_005863.4
UniGeneiHs.25155

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

DNASUi10276
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10276

Organism-specific databases

CTDi10276
EuPathDBiHostDB:ENSG00000173848.18

Phylogenomic databases

eggNOGiKOG4305 Eukaryota
COG5422 LUCA
HOGENOMiHOG000034044
HOVERGENiHBG050567

Miscellaneous databases

ChiTaRSiNET1 human
GenomeRNAii10276

Gene expression databases

BgeeiENSG00000173848 Expressed in 237 organ(s), highest expression level in tendon

Family and domain databases

CDDicd13224 PH_Net1, 1 hit
cd00160 RhoGEF, 1 hit
Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR001331 GDS_CDC24_CS
IPR037853 Net1_PH
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00621 RhoGEF, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00325 RhoGEF, 1 hit
SUPFAMiSSF48065 SSF48065, 1 hit
PROSITEiView protein in PROSITE
PS00741 DH_1, 1 hit
PS50010 DH_2, 1 hit
PS50003 PH_DOMAIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5SQI7_HUMAN
AccessioniPrimary (citable) accession number: Q5SQI7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: October 10, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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