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UniProtKB - Q5SQH8 (CF136_HUMAN)

Entry version 127 (02 Dec 2020)
Sequence version 1 (21 Dec 2004)
Previous versions | rss
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Protein

Uncharacterized protein C6orf136

Gene

C6orf136

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q5SQH8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C6orf136
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:C6orf136
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000204564.11

Human Gene Nomenclature Database

More...HGNCi		HGNC:21301, C6orf136

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5SQH8

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000204564

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134962744

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q5SQH8, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		C6orf136

Domain mapping of disease mutations (DMDM)

More...DMDMi		71658797

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000895311 – 315Uncharacterized protein C6orf136Add BLAST315

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q5SQH8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q5SQH8

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q5SQH8

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5SQH8

PeptideAtlas

More...PeptideAtlasi		Q5SQH8

PRoteomics IDEntifications database

More...PRIDEi		Q5SQH8

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		29053
63798 [Q5SQH8-1]
63799 [Q5SQH8-2]
63800 [Q5SQH8-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5SQH8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5SQH8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000204564, Expressed in left ventricle myocardium and 205 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q5SQH8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5SQH8, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000204564, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		128738, 8 interactors

Protein interaction database and analysis system

More...IntActi		Q5SQH8, 2 interactors

Molecular INTeraction database

More...MINTi		Q5SQH8

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000293604

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5SQH8, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4457, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000008658

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_555426_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5SQH8

Identification of Orthologs from Complete Genome Data

More...OMAi		PELHRGC

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5SQH8

TreeFam database of animal gene trees

More...TreeFami		TF313961

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR018790, DUF2358

The PANTHER Classification System

More...PANTHERi		PTHR31094, PTHR31094, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF10184, DUF2358, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 9 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5SQH8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MYQPSRGAAR RLGPCLRAYQ ARPQDQLYPG TLPFPPLWPH STTTTSPSSP 
        60         70         80         90        100
LFWSPLPPRL PTQRLPQVPP LPLPQIQALS SAWVVLPPGK GEEGPGPELH 
       110        120        130        140        150
SGCLDGLRSL FEGPPCPYPG AWIPFQVPGT AHPSPATPSG DPSMEEHLSV 
       160        170        180        190        200
MYERLRQELP KLFLQSHDYS LYSLDVEFIN EILNIRTKGR TWYILSLTLC 
       210        220        230        240        250
RFLAWNYFAH LRLEVLQLTR HPENWTLQAR WRLVGLPVHL LFLRFYKRDK 
       260        270        280        290        300
DEHYRTYDAY STFYLNSSGL ICRHRLDKLM PSHSPPTPVK KLLVGALVAL 
       310 
GLSEPEPDLN LCSKP
Length:315
Mass (Da):35,794
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i01C9883DA956EB35
GO
Isoform 2 (identifier: Q5SQH8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-143: Missing.

Show »
Length:172
Mass (Da):20,490
Checksum:i157D85CB50329E0F
GO
Isoform 3 (identifier: Q5SQH8-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     25-158: Missing.

Show »
Length:181
Mass (Da):21,287
Checksum:iB6B9E76EF32C71CF
GO
Isoform 4 (identifier: Q5SQH8-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     24-24: Q → QVSGGEEGGR...GASRTPSGTE

Show »
Length:496
Mass (Da):54,721
Checksum:i5DA16F1C42D72891
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C4U4H7C4U4_HUMAN
Uncharacterized protein C6orf136
C6orf136
104Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q0P5T2Q0P5T2_HUMAN
C6orf136 protein
C6orf136
433Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140T9G8A0A140T9G8_HUMAN
Uncharacterized protein C6orf136
C6orf136
433Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C4Z6H7C4Z6_HUMAN
Uncharacterized protein C6orf136
C6orf136
48Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C5D3H7C5D3_HUMAN
Uncharacterized protein C6orf136
C6orf136
95Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WEV2F8WEV2_HUMAN
Uncharacterized protein C6orf136
C6orf136
188Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C5B5H7C5B5_HUMAN
Uncharacterized protein C6orf136
C6orf136
28Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WBB4F8WBB4_HUMAN
Uncharacterized protein C6orf136
C6orf136
58Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WC77F8WC77_HUMAN
Uncharacterized protein C6orf136
C6orf136
90Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti187T → S in BAC87037 (PubMed:14702039).Curated1
Sequence conflicti283H → P in BAC87037 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0146181 – 143Missing in isoform 2. 1 PublicationAdd BLAST143
Alternative sequenceiVSP_04664024Q → QVSGGEEGGRRGGGERPSSK PVRGAERALGSAQAQRHPPP LPTCALQRVDRLGVAGAGGR RCRACRARTSVLPGLRAVRR GQGQAAGRVCVAPDSPRLPV PRGDLKGRGREIRSPAAAPS RSSPAQTRPAGRPQQPARLA LGERSWQEGRPVCTRFGPLR PGWQDGHAPSRDGASRTPSG TE in isoform 4. Curated1
Alternative sequenceiVSP_01461925 – 158Missing in isoform 3. CuratedAdd BLAST134

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK127564 mRNA Translation: BAC87037.1
AL662798 Genomic DNA No translation available.
AL662800 Genomic DNA No translation available.
AL732442 Genomic DNA No translation available.
AL845353 Genomic DNA No translation available.
BX119957 Genomic DNA No translation available.
BX908728 Genomic DNA No translation available.
CR753328 Genomic DNA No translation available.
CR759778 Genomic DNA No translation available.
BC016167 mRNA Translation: AAH16167.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS43443.1 [Q5SQH8-1]
CCDS4684.2 [Q5SQH8-3]
CCDS54979.1 [Q5SQH8-4]

NCBI Reference Sequences

More...RefSeqi		NP_001103408.1, NM_001109938.2 [Q5SQH8-1]
NP_659466.2, NM_145029.3 [Q5SQH8-3]
XP_011512686.1, XM_011514384.1 [Q5SQH8-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000293604; ENSP00000293604; ENSG00000204564 [Q5SQH8-4]
ENST00000376471; ENSP00000365654; ENSG00000204564 [Q5SQH8-3]
ENST00000376473; ENSP00000365656; ENSG00000204564 [Q5SQH8-1]
ENST00000383580; ENSP00000373074; ENSG00000206487 [Q5SQH8-3]
ENST00000383581; ENSP00000373075; ENSG00000206487 [Q5SQH8-1]
ENST00000415931; ENSP00000402805; ENSG00000233164 [Q5SQH8-3]
ENST00000417076; ENSP00000405594; ENSG00000237100 [Q5SQH8-3]
ENST00000417649; ENSP00000395979; ENSG00000233641 [Q5SQH8-3]
ENST00000419321; ENSP00000398769; ENSG00000237100 [Q5SQH8-1]
ENST00000422530; ENSP00000390275; ENSG00000237012 [Q5SQH8-1]
ENST00000425581; ENSP00000404588; ENSG00000233641 [Q5SQH8-1]
ENST00000430141; ENSP00000396916; ENSG00000224120 [Q5SQH8-1]
ENST00000447505; ENSP00000415915; ENSG00000233164 [Q5SQH8-1]
ENST00000455682; ENSP00000391657; ENSG00000224120 [Q5SQH8-3]
ENST00000456444; ENSP00000387592; ENSG00000237012 [Q5SQH8-3]
ENST00000651131; ENSP00000499201; ENSG00000204564 [Q5SQH8-4]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		221545

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:221545

UCSC genome browser

More...UCSCi		uc003nqw.5, human [Q5SQH8-1]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK127564 mRNA Translation: BAC87037.1
AL662798 Genomic DNA No translation available.
AL662800 Genomic DNA No translation available.
AL732442 Genomic DNA No translation available.
AL845353 Genomic DNA No translation available.
BX119957 Genomic DNA No translation available.
BX908728 Genomic DNA No translation available.
CR753328 Genomic DNA No translation available.
CR759778 Genomic DNA No translation available.
BC016167 mRNA Translation: AAH16167.1
CCDSiCCDS43443.1 [Q5SQH8-1]
CCDS4684.2 [Q5SQH8-3]
CCDS54979.1 [Q5SQH8-4]
RefSeqiNP_001103408.1, NM_001109938.2 [Q5SQH8-1]
NP_659466.2, NM_145029.3 [Q5SQH8-3]
XP_011512686.1, XM_011514384.1 [Q5SQH8-2]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi128738, 8 interactors
IntActiQ5SQH8, 2 interactors
MINTiQ5SQH8
STRINGi9606.ENSP00000293604

PTM databases

iPTMnetiQ5SQH8
PhosphoSitePlusiQ5SQH8

Polymorphism and mutation databases

BioMutaiC6orf136
DMDMi71658797

Proteomic databases

jPOSTiQ5SQH8
MassIVEiQ5SQH8
MaxQBiQ5SQH8
PaxDbiQ5SQH8
PeptideAtlasiQ5SQH8
PRIDEiQ5SQH8
ProteomicsDBi29053
63798 [Q5SQH8-1]
63799 [Q5SQH8-2]
63800 [Q5SQH8-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		55864, 90 antibodies

The DNASU plasmid repository

More...DNASUi		221545

Genome annotation databases

EnsembliENST00000293604; ENSP00000293604; ENSG00000204564 [Q5SQH8-4]
ENST00000376471; ENSP00000365654; ENSG00000204564 [Q5SQH8-3]
ENST00000376473; ENSP00000365656; ENSG00000204564 [Q5SQH8-1]
ENST00000383580; ENSP00000373074; ENSG00000206487 [Q5SQH8-3]
ENST00000383581; ENSP00000373075; ENSG00000206487 [Q5SQH8-1]
ENST00000415931; ENSP00000402805; ENSG00000233164 [Q5SQH8-3]
ENST00000417076; ENSP00000405594; ENSG00000237100 [Q5SQH8-3]
ENST00000417649; ENSP00000395979; ENSG00000233641 [Q5SQH8-3]
ENST00000419321; ENSP00000398769; ENSG00000237100 [Q5SQH8-1]
ENST00000422530; ENSP00000390275; ENSG00000237012 [Q5SQH8-1]
ENST00000425581; ENSP00000404588; ENSG00000233641 [Q5SQH8-1]
ENST00000430141; ENSP00000396916; ENSG00000224120 [Q5SQH8-1]
ENST00000447505; ENSP00000415915; ENSG00000233164 [Q5SQH8-1]
ENST00000455682; ENSP00000391657; ENSG00000224120 [Q5SQH8-3]
ENST00000456444; ENSP00000387592; ENSG00000237012 [Q5SQH8-3]
ENST00000651131; ENSP00000499201; ENSG00000204564 [Q5SQH8-4]
GeneIDi221545
KEGGihsa:221545
UCSCiuc003nqw.5, human [Q5SQH8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		221545
EuPathDBiHostDB:ENSG00000204564.11

GeneCards: human genes, protein and diseases

More...GeneCardsi		C6orf136
HGNCiHGNC:21301, C6orf136
HPAiENSG00000204564, Low tissue specificity
neXtProtiNX_Q5SQH8
OpenTargetsiENSG00000204564
PharmGKBiPA134962744

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4457, Eukaryota
GeneTreeiENSGT00390000008658
HOGENOMiCLU_555426_0_0_1
InParanoidiQ5SQH8
OMAiPELHRGC
PhylomeDBiQ5SQH8
TreeFamiTF313961

Enzyme and pathway databases

PathwayCommonsiQ5SQH8

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		221545, 29 hits in 850 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		221545
PharosiQ5SQH8, Tdark

Protein Ontology

More...PROi		PR:Q5SQH8
RNActiQ5SQH8, protein

Gene expression databases

BgeeiENSG00000204564, Expressed in left ventricle myocardium and 205 other tissues
ExpressionAtlasiQ5SQH8, baseline and differential
GenevisibleiQ5SQH8, HS

Family and domain databases

InterProiView protein in InterPro
IPR018790, DUF2358
PANTHERiPTHR31094, PTHR31094, 1 hit
PfamiView protein in Pfam
PF10184, DUF2358, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCF136_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5SQH8
Secondary accession number(s): A9R9P9
, F8VX15, Q5SU01, Q6ZSB7, Q8TB84
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 2, 2005
Last sequence update: December 21, 2004
Last modified: December 2, 2020
This is version 127 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
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