ANKRD20A2

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Ankyrin repeat domain-containing protein 20A2
Gene namesⁱ	Name:ANKRD20A2
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 9

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000183148.6
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:31979 ANKRD20A2
neXtProtⁱ	NX_Q5SQ80

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA142672619

PharmGKBⁱ

PA142672619

Polymorphism and mutation databases

BioMutaⁱ	ANKRD20A2
DMDMⁱ	74743522

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000240837	1 – 823	Ankyrin repeat domain-containing protein 20A2Add BLAST		823

Proteomic databases

EPDⁱ	Q5SQ80
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q5SQ80
PaxDbⁱ	Q5SQ80
PeptideAtlas More...PeptideAtlasⁱ	Q5SQ80
PRIDEⁱ	Q5SQ80
ProteomicsDBⁱ	63791

PTM databases

iPTMnetⁱ	Q5SQ80
PhosphoSitePlusⁱ	Q5SQ80

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000183148 Expressed in 71 organ(s), highest expression level in testis
CleanExⁱ	HS_ANKRD20A2
ExpressionAtlasⁱ	Q5SQ80 baseline and differential
Genevisibleⁱ	Q5SQ80 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA043239 HPA047112 HPA047167 HPA047766 HPA051753

HPAⁱ

HPA043239
HPA047112
HPA047167
HPA047766
HPA051753

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000366826

STRINGⁱ

9606.ENSP00000366826

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q5SQ80
SMRⁱ	Q5SQ80
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Repeatⁱ	66 – 95	ANK 1Add BLAST	30
Repeatⁱ	99 – 128	ANK 2Add BLAST	30
Repeatⁱ	132 – 161	ANK 3Add BLAST	30
Repeatⁱ	165 – 194	ANK 4Add BLAST	30
Repeatⁱ	198 – 227	ANK 5Add BLAST	30

Coiled coil

Feature key	Position(s)	DescriptionActions	Length
Coiled coilⁱ	431 – 480	Sequence analysisAdd BLAST	50
Coiled coilⁱ	565 – 724	Sequence analysisAdd BLAST	160
Coiled coilⁱ	776 – 805	Sequence analysisAdd BLAST	30

Keywords - Domainⁱ

ANK repeat, Coiled coil, Repeat

Phylogenomic databases

eggNOGⁱ	KOG0504 Eukaryota COG0666 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00560000076605
HOGENOMⁱ	HOG000230851
HOVERGENⁱ	HBG079958
InParanoidⁱ	Q5SQ80
KEGG Orthology (KO) More...KOⁱ	K17299
OMAⁱ	PSTEMED
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G077A
PhylomeDBⁱ	Q5SQ80
TreeFamⁱ	TF333496

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00204 ANK, 2 hits
Gene3Dⁱ	1.25.40.20, 2 hits
InterProⁱ	View protein in InterPro IPR002110 Ankyrin_rpt IPR020683 Ankyrin_rpt-contain_dom IPR036770 Ankyrin_rpt-contain_sf IPR039497 CC144C-like_CC_dom
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF12796 Ank_2, 2 hits PF14915 CCDC144C, 1 hit
PRINTSⁱ	PR01415 ANKYRIN
SMARTⁱ	View protein in SMART SM00248 ANK, 6 hits
SUPFAMⁱ	SSF48403 SSF48403, 1 hit
PROSITEⁱ	View protein in PROSITE PS50297 ANK_REP_REGION, 1 hit PS50088 ANK_REPEAT, 4 hits

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

Q5SQ80-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKLFGFGSRR GQTAQGSIDH VYTGSGYRIR DSELQKIHRA AVKGDAAEVE 
        60         70         80         90        100
RCLARRSGDL DALDKQHRTA LHLACASGHV QVVTLLVNRK CQIDVCDKEN 
       110        120        130        140        150
RTPLIQAVHC QEEACAVILL EHGANPNLKD IYGNTALHYA VYSESTSLAE 
       160        170        180        190        200
KLLSHGAHIE ALDKDNNTPL LFAIICKKEK MVEFLLKRKA SSHAVDRLRR 
       210        220        230        240        250
SALMLAVYYD SPGIVNILLK QNIDVFAQDM CGRDAEDYAI SHHLTKIQQQ 
       260        270        280        290        300
ILEHKKKILK KEKSDVGSSD ESAVSIFHEL RVDSLPASDD KDLNVATKQC 
       310        320        330        340        350
VPEKVSEPLP GSSHEKGNRI VNGQGEGPPA KHPSLKPSTE VEDPAVKGAV 
       360        370        380        390        400
QRKNVQTLRA EQALPVASEE EQERHERSEK KQPQVKEGNN TNKSEKIQLS 
       410        420        430        440        450
ENICDSTSSA AAGRLTQQRK IGKTYPQQFP KKLKEEHDRC TLKQENEEKT 
       460        470        480        490        500
NVNMLYKKNR EELERKEKQY KKEVEAKQLE PTVQSLEMKS KTARNTPNRD 
       510        520        530        540        550
FHNHEEMKGL MDENCILKAD IAILRQEICT MKNDNLEKEN KYLKDIKIVK 
       560        570        580        590        600
ETNAALEKYI KLNEEMITET AFRYQQELND LKAENTRLNA ELLKEKESKK 
       610        620        630        640        650
RLEADIESYQ SRLAAAISKH SESVKTERNL KLALERTRDV SVQVEMSSAI 
       660        670        680        690        700
SKVKDENEFL TEQLSETQIK FNALKDKFRK TRDSLRKKSL ALETVQNDLS 
       710        720        730        740        750
QTQQQTQEMK EMYQNAEAKV NNSTGKWNCV EERICHLQRE NAWLVQQLDD 
       760        770        780        790        800
VHQKEDHKEI VTNIQRGFIE SGKKDLVLEE KSKKLMNECD HLKESLFQYE 
       810        820 
REKTEGVVSI KEDKYFQTSR KKI

Length:823

Mass (Da):94,087

Last modified:December 21, 2004 - v1

Checksum:ⁱ6C1C478C3EE9B67F

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	A0A087X1P9	A0A087X1P9_HUMAN		Ankyrin repeat domain-containing pr... Ankyrin repeat domain-containing protein 20A2	ANKRD20A2	142	Annotation score:

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL773545 Genomic DNA No translation available. BX664727 Genomic DNA No translation available.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS35028.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001012421.1, NM_001012421.1
UniGeneⁱ	Hs.632663

Genome annotation databases

Ensemblⁱ	ENST00000377601; ENSP00000366826; ENSG00000183148
GeneIDⁱ	441430
KEGGⁱ	hsa:441430
UCSC genome browser More...UCSCⁱ	uc004acd.4 human

Protein	Similar proteins		Species	Score	Length	Source
Q5SQ80	Ankyrin repeat domain-containing protein 20B		HUMAN		823	UniRef90_Q5CZ79
Ankyrin repeat domain-containing protein 20A1		HUMAN		823
Ankyrin repeat domain-containing protein 20A3		HUMAN		823
Ankyrin repeat domain-containing protein 20A4		HUMAN		823
ANKRD20A2 protein		HUMAN		822
+7

Protein	Similar proteins		Species	Score	Length	Source
Q5SQ80	Ankyrin repeat domain-containing protein 20B		HUMAN		823	UniRef50_Q5CZ79
Uncharacterized protein		PANTR		788
Uncharacterized protein		GORGO		762
Uncharacterized protein		COLAP		735
Uncharacterized protein		NOMLE		707
+22

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL773545 Genomic DNA No translation available. BX664727 Genomic DNA No translation available.
CCDSⁱ	CCDS35028.1
RefSeqⁱ	NP_001012421.1, NM_001012421.1
UniGeneⁱ	Hs.632663

3D structure databases

ProteinModelPortalⁱ	Q5SQ80
SMRⁱ	Q5SQ80
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000366826

STRINGⁱ

9606.ENSP00000366826

PTM databases

iPTMnetⁱ	Q5SQ80
PhosphoSitePlusⁱ	Q5SQ80

Polymorphism and mutation databases

BioMutaⁱ	ANKRD20A2
DMDMⁱ	74743522

Proteomic databases

EPDⁱ	Q5SQ80
MaxQBⁱ	Q5SQ80
PaxDbⁱ	Q5SQ80
PeptideAtlasⁱ	Q5SQ80
PRIDEⁱ	Q5SQ80
ProteomicsDBⁱ	63791

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000377601; ENSP00000366826; ENSG00000183148
GeneIDⁱ	441430
KEGGⁱ	hsa:441430
UCSCⁱ	uc004acd.4 human

Organism-specific databases

CTDⁱ	441430
EuPathDBⁱ	HostDB:ENSG00000183148.6
GeneCardsⁱ	ANKRD20A2
HGNCⁱ	HGNC:31979 ANKRD20A2
HPAⁱ	HPA043239 HPA047112 HPA047167 HPA047766 HPA051753
neXtProtⁱ	NX_Q5SQ80
PharmGKBⁱ	PA142672619
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0504 Eukaryota COG0666 LUCA
GeneTreeⁱ	ENSGT00560000076605
HOGENOMⁱ	HOG000230851
HOVERGENⁱ	HBG079958
InParanoidⁱ	Q5SQ80
KOⁱ	K17299
OMAⁱ	PSTEMED
OrthoDBⁱ	EOG091G077A
PhylomeDBⁱ	Q5SQ80
TreeFamⁱ	TF333496

Miscellaneous databases

GenomeRNAiⁱ	441430
Protein Ontology More...PROⁱ	PR:Q5SQ80

Gene expression databases

Bgeeⁱ	ENSG00000183148 Expressed in 71 organ(s), highest expression level in testis
CleanExⁱ	HS_ANKRD20A2
ExpressionAtlasⁱ	Q5SQ80 baseline and differential
Genevisibleⁱ	Q5SQ80 HS

Family and domain databases

CDDⁱ	cd00204 ANK, 2 hits
Gene3Dⁱ	1.25.40.20, 2 hits
InterProⁱ	View protein in InterPro IPR002110 Ankyrin_rpt IPR020683 Ankyrin_rpt-contain_dom IPR036770 Ankyrin_rpt-contain_sf IPR039497 CC144C-like_CC_dom
Pfamⁱ	View protein in Pfam PF12796 Ank_2, 2 hits PF14915 CCDC144C, 1 hit
PRINTSⁱ	PR01415 ANKYRIN
SMARTⁱ	View protein in SMART SM00248 ANK, 6 hits
SUPFAMⁱ	SSF48403 SSF48403, 1 hit
PROSITEⁱ	View protein in PROSITE PS50297 ANK_REP_REGION, 1 hit PS50088 ANK_REPEAT, 4 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A20A2_HUMAN
Accessionⁱ	Q5SQ80Primary (citable) accession number: Q5SQ80
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
	Last sequence update:	December 21, 2004
	Last modified:	October 10, 2018
	This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 9
Human chromosome 9: entries, gene names and cross-references to MIM

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UniParc

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UniRef

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UniProtKB - Q5SQ80 (A20A2_HUMAN)

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Ankyrin repeat domain-containing protein 20A2

Select a section on the left to see content.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ