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Protein

Ankyrin repeat domain-containing protein 20A2

Gene

ANKRD20A2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Recommended name:
Ankyrin repeat domain-containing protein 20A2
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000183148.6
HGNCiHGNC:31979 ANKRD20A2
neXtProtiNX_Q5SQ80

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142672619

Polymorphism and mutation databases

BioMutaiANKRD20A2
DMDMi74743522

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002408371 – 823Ankyrin repeat domain-containing protein 20A2Add BLAST823

Proteomic databases

EPDiQ5SQ80
MaxQBiQ5SQ80
PaxDbiQ5SQ80
PeptideAtlasiQ5SQ80
PRIDEiQ5SQ80
ProteomicsDBi63791

PTM databases

iPTMnetiQ5SQ80
PhosphoSitePlusiQ5SQ80

Expressioni

Gene expression databases

BgeeiENSG00000183148 Expressed in 71 organ(s), highest expression level in testis
CleanExiHS_ANKRD20A2
ExpressionAtlasiQ5SQ80 baseline and differential
GenevisibleiQ5SQ80 HS

Organism-specific databases

HPAiHPA043239
HPA047112
HPA047167
HPA047766
HPA051753

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000366826

Structurei

3D structure databases

ProteinModelPortaliQ5SQ80
SMRiQ5SQ80
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati66 – 95ANK 1Add BLAST30
Repeati99 – 128ANK 2Add BLAST30
Repeati132 – 161ANK 3Add BLAST30
Repeati165 – 194ANK 4Add BLAST30
Repeati198 – 227ANK 5Add BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili431 – 480Sequence analysisAdd BLAST50
Coiled coili565 – 724Sequence analysisAdd BLAST160
Coiled coili776 – 805Sequence analysisAdd BLAST30

Keywords - Domaini

ANK repeat, Coiled coil, Repeat

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00560000076605
HOGENOMiHOG000230851
HOVERGENiHBG079958
InParanoidiQ5SQ80
KOiK17299
OMAiPSTEMED
OrthoDBiEOG091G077A
PhylomeDBiQ5SQ80
TreeFamiTF333496

Family and domain databases

CDDicd00204 ANK, 2 hits
Gene3Di1.25.40.20, 2 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR039497 CC144C-like_CC_dom
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF14915 CCDC144C, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 6 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 4 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5SQ80-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLFGFGSRR GQTAQGSIDH VYTGSGYRIR DSELQKIHRA AVKGDAAEVE
60 70 80 90 100
RCLARRSGDL DALDKQHRTA LHLACASGHV QVVTLLVNRK CQIDVCDKEN
110 120 130 140 150
RTPLIQAVHC QEEACAVILL EHGANPNLKD IYGNTALHYA VYSESTSLAE
160 170 180 190 200
KLLSHGAHIE ALDKDNNTPL LFAIICKKEK MVEFLLKRKA SSHAVDRLRR
210 220 230 240 250
SALMLAVYYD SPGIVNILLK QNIDVFAQDM CGRDAEDYAI SHHLTKIQQQ
260 270 280 290 300
ILEHKKKILK KEKSDVGSSD ESAVSIFHEL RVDSLPASDD KDLNVATKQC
310 320 330 340 350
VPEKVSEPLP GSSHEKGNRI VNGQGEGPPA KHPSLKPSTE VEDPAVKGAV
360 370 380 390 400
QRKNVQTLRA EQALPVASEE EQERHERSEK KQPQVKEGNN TNKSEKIQLS
410 420 430 440 450
ENICDSTSSA AAGRLTQQRK IGKTYPQQFP KKLKEEHDRC TLKQENEEKT
460 470 480 490 500
NVNMLYKKNR EELERKEKQY KKEVEAKQLE PTVQSLEMKS KTARNTPNRD
510 520 530 540 550
FHNHEEMKGL MDENCILKAD IAILRQEICT MKNDNLEKEN KYLKDIKIVK
560 570 580 590 600
ETNAALEKYI KLNEEMITET AFRYQQELND LKAENTRLNA ELLKEKESKK
610 620 630 640 650
RLEADIESYQ SRLAAAISKH SESVKTERNL KLALERTRDV SVQVEMSSAI
660 670 680 690 700
SKVKDENEFL TEQLSETQIK FNALKDKFRK TRDSLRKKSL ALETVQNDLS
710 720 730 740 750
QTQQQTQEMK EMYQNAEAKV NNSTGKWNCV EERICHLQRE NAWLVQQLDD
760 770 780 790 800
VHQKEDHKEI VTNIQRGFIE SGKKDLVLEE KSKKLMNECD HLKESLFQYE
810 820
REKTEGVVSI KEDKYFQTSR KKI
Length:823
Mass (Da):94,087
Last modified:December 21, 2004 - v1
Checksum:i6C1C478C3EE9B67F
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087X1P9A0A087X1P9_HUMAN
Ankyrin repeat domain-containing pr...
ANKRD20A2
142Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL773545 Genomic DNA No translation available.
BX664727 Genomic DNA No translation available.
CCDSiCCDS35028.1
RefSeqiNP_001012421.1, NM_001012421.1
UniGeneiHs.632663

Genome annotation databases

EnsembliENST00000377601; ENSP00000366826; ENSG00000183148
GeneIDi441430
KEGGihsa:441430
UCSCiuc004acd.4 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL773545 Genomic DNA No translation available.
BX664727 Genomic DNA No translation available.
CCDSiCCDS35028.1
RefSeqiNP_001012421.1, NM_001012421.1
UniGeneiHs.632663

3D structure databases

ProteinModelPortaliQ5SQ80
SMRiQ5SQ80
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000366826

PTM databases

iPTMnetiQ5SQ80
PhosphoSitePlusiQ5SQ80

Polymorphism and mutation databases

BioMutaiANKRD20A2
DMDMi74743522

Proteomic databases

EPDiQ5SQ80
MaxQBiQ5SQ80
PaxDbiQ5SQ80
PeptideAtlasiQ5SQ80
PRIDEiQ5SQ80
ProteomicsDBi63791

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000377601; ENSP00000366826; ENSG00000183148
GeneIDi441430
KEGGihsa:441430
UCSCiuc004acd.4 human

Organism-specific databases

CTDi441430
EuPathDBiHostDB:ENSG00000183148.6
GeneCardsiANKRD20A2
HGNCiHGNC:31979 ANKRD20A2
HPAiHPA043239
HPA047112
HPA047167
HPA047766
HPA051753
neXtProtiNX_Q5SQ80
PharmGKBiPA142672619
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00560000076605
HOGENOMiHOG000230851
HOVERGENiHBG079958
InParanoidiQ5SQ80
KOiK17299
OMAiPSTEMED
OrthoDBiEOG091G077A
PhylomeDBiQ5SQ80
TreeFamiTF333496

Miscellaneous databases

GenomeRNAii441430
PROiPR:Q5SQ80

Gene expression databases

BgeeiENSG00000183148 Expressed in 71 organ(s), highest expression level in testis
CleanExiHS_ANKRD20A2
ExpressionAtlasiQ5SQ80 baseline and differential
GenevisibleiQ5SQ80 HS

Family and domain databases

CDDicd00204 ANK, 2 hits
Gene3Di1.25.40.20, 2 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR039497 CC144C-like_CC_dom
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF14915 CCDC144C, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 6 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA20A2_HUMAN
AccessioniPrimary (citable) accession number: Q5SQ80
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: December 21, 2004
Last modified: October 10, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
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