UniProtKB - Q5SQ80 (A20A2_HUMAN)
Protein
Putative ankyrin repeat domain-containing protein 20A2
Gene
ANKRD20A2P
Organism
Homo sapiens (Human)
Status
Functioni
Caution
Could be the product of a pseudogene.Curated
Enzyme and pathway databases
PathwayCommonsi | Q5SQ80 |
Names & Taxonomyi
Protein namesi | Recommended name: Putative ankyrin repeat domain-containing protein 20A2Alternative name(s): Ankyrin repeat domain-containing protein 20A2 pseudogeneImported |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000183148.6 |
HGNCi | HGNC:31979, ANKRD20A2P |
neXtProti | NX_Q5SQ80 |
Pathology & Biotechi
Organism-specific databases
PharmGKBi | PA142672619 |
Miscellaneous databases
Pharosi | Q5SQ80, Tdark |
Polymorphism and mutation databases
BioMutai | ANKRD20A2 |
DMDMi | 74743522 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000240837 | 1 – 823 | Putative ankyrin repeat domain-containing protein 20A2Add BLAST | 823 |
Proteomic databases
EPDi | Q5SQ80 |
jPOSTi | Q5SQ80 |
MassIVEi | Q5SQ80 |
MaxQBi | Q5SQ80 |
PaxDbi | Q5SQ80 |
PeptideAtlasi | Q5SQ80 |
PRIDEi | Q5SQ80 |
ProteomicsDBi | 63791 |
PTM databases
iPTMneti | Q5SQ80 |
PhosphoSitePlusi | Q5SQ80 |
Expressioni
Gene expression databases
Bgeei | ENSG00000183148, Expressed in sural nerve and 90 other tissues |
ExpressionAtlasi | Q5SQ80, baseline and differential |
Genevisiblei | Q5SQ80, HS |
Organism-specific databases
HPAi | ENSG00000183148, Tissue enriched (testis) |
Interactioni
Protein-protein interaction databases
STRINGi | 9606.ENSP00000366826 |
Miscellaneous databases
RNActi | Q5SQ80, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 66 – 95 | ANK 1Add BLAST | 30 | |
Repeati | 99 – 128 | ANK 2Add BLAST | 30 | |
Repeati | 132 – 161 | ANK 3Add BLAST | 30 | |
Repeati | 165 – 194 | ANK 4Add BLAST | 30 | |
Repeati | 198 – 227 | ANK 5Add BLAST | 30 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 431 – 480 | Sequence analysisAdd BLAST | 50 | |
Coiled coili | 565 – 724 | Sequence analysisAdd BLAST | 160 | |
Coiled coili | 776 – 805 | Sequence analysisAdd BLAST | 30 |
Keywords - Domaini
ANK repeat, Coiled coil, RepeatPhylogenomic databases
eggNOGi | KOG0504, Eukaryota |
GeneTreei | ENSGT00940000163801 |
HOGENOMi | CLU_001111_3_0_1 |
InParanoidi | Q5SQ80 |
OMAi | TQDISEQ |
OrthoDBi | 294605at2759 |
PhylomeDBi | Q5SQ80 |
TreeFami | TF333496 |
Family and domain databases
Gene3Di | 1.25.40.20, 2 hits |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR039497, CC144C-like_CC_dom |
Pfami | View protein in Pfam PF12796, Ank_2, 2 hits PF14915, CCDC144C, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 6 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 4 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q5SQ80-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKLFGFGSRR GQTAQGSIDH VYTGSGYRIR DSELQKIHRA AVKGDAAEVE
60 70 80 90 100
RCLARRSGDL DALDKQHRTA LHLACASGHV QVVTLLVNRK CQIDVCDKEN
110 120 130 140 150
RTPLIQAVHC QEEACAVILL EHGANPNLKD IYGNTALHYA VYSESTSLAE
160 170 180 190 200
KLLSHGAHIE ALDKDNNTPL LFAIICKKEK MVEFLLKRKA SSHAVDRLRR
210 220 230 240 250
SALMLAVYYD SPGIVNILLK QNIDVFAQDM CGRDAEDYAI SHHLTKIQQQ
260 270 280 290 300
ILEHKKKILK KEKSDVGSSD ESAVSIFHEL RVDSLPASDD KDLNVATKQC
310 320 330 340 350
VPEKVSEPLP GSSHEKGNRI VNGQGEGPPA KHPSLKPSTE VEDPAVKGAV
360 370 380 390 400
QRKNVQTLRA EQALPVASEE EQERHERSEK KQPQVKEGNN TNKSEKIQLS
410 420 430 440 450
ENICDSTSSA AAGRLTQQRK IGKTYPQQFP KKLKEEHDRC TLKQENEEKT
460 470 480 490 500
NVNMLYKKNR EELERKEKQY KKEVEAKQLE PTVQSLEMKS KTARNTPNRD
510 520 530 540 550
FHNHEEMKGL MDENCILKAD IAILRQEICT MKNDNLEKEN KYLKDIKIVK
560 570 580 590 600
ETNAALEKYI KLNEEMITET AFRYQQELND LKAENTRLNA ELLKEKESKK
610 620 630 640 650
RLEADIESYQ SRLAAAISKH SESVKTERNL KLALERTRDV SVQVEMSSAI
660 670 680 690 700
SKVKDENEFL TEQLSETQIK FNALKDKFRK TRDSLRKKSL ALETVQNDLS
710 720 730 740 750
QTQQQTQEMK EMYQNAEAKV NNSTGKWNCV EERICHLQRE NAWLVQQLDD
760 770 780 790 800
VHQKEDHKEI VTNIQRGFIE SGKKDLVLEE KSKKLMNECD HLKESLFQYE
810 820
REKTEGVVSI KEDKYFQTSR KKI
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A087X1P9 | A0A087X1P9_HUMAN | Putative ankyrin repeat domain-cont... | ANKRD20A2P | 142 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL773545 Genomic DNA No translation available. BX664727 Genomic DNA No translation available. |
RefSeqi | NP_001012421.1, NM_001012421.1 |
Genome annotation databases
Ensembli | ENST00000377601; ENSP00000366826; ENSG00000183148 |
UCSCi | uc004acd.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL773545 Genomic DNA No translation available. BX664727 Genomic DNA No translation available. |
RefSeqi | NP_001012421.1, NM_001012421.1 |
3D structure databases
SMRi | Q5SQ80 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 9606.ENSP00000366826 |
PTM databases
iPTMneti | Q5SQ80 |
PhosphoSitePlusi | Q5SQ80 |
Polymorphism and mutation databases
BioMutai | ANKRD20A2 |
DMDMi | 74743522 |
Proteomic databases
EPDi | Q5SQ80 |
jPOSTi | Q5SQ80 |
MassIVEi | Q5SQ80 |
MaxQBi | Q5SQ80 |
PaxDbi | Q5SQ80 |
PeptideAtlasi | Q5SQ80 |
PRIDEi | Q5SQ80 |
ProteomicsDBi | 63791 |
Protocols and materials databases
Antibodypediai | 71388, 3 antibodies |
Genome annotation databases
Ensembli | ENST00000377601; ENSP00000366826; ENSG00000183148 |
UCSCi | uc004acd.4, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000183148.6 |
GeneCardsi | ANKRD20A2P |
HGNCi | HGNC:31979, ANKRD20A2P |
HPAi | ENSG00000183148, Tissue enriched (testis) |
neXtProti | NX_Q5SQ80 |
PharmGKBi | PA142672619 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0504, Eukaryota |
GeneTreei | ENSGT00940000163801 |
HOGENOMi | CLU_001111_3_0_1 |
InParanoidi | Q5SQ80 |
OMAi | TQDISEQ |
OrthoDBi | 294605at2759 |
PhylomeDBi | Q5SQ80 |
TreeFami | TF333496 |
Enzyme and pathway databases
PathwayCommonsi | Q5SQ80 |
Miscellaneous databases
BioGRID-ORCSi | 441430, 347 hits in 428 CRISPR screens |
GenomeRNAii | 441430 |
Pharosi | Q5SQ80, Tdark |
PROi | PR:Q5SQ80 |
RNActi | Q5SQ80, protein |
Gene expression databases
Bgeei | ENSG00000183148, Expressed in sural nerve and 90 other tissues |
ExpressionAtlasi | Q5SQ80, baseline and differential |
Genevisiblei | Q5SQ80, HS |
Family and domain databases
Gene3Di | 1.25.40.20, 2 hits |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR039497, CC144C-like_CC_dom |
Pfami | View protein in Pfam PF12796, Ank_2, 2 hits PF14915, CCDC144C, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 6 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 4 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A20A2_HUMAN | |
Accessioni | Q5SQ80Primary (citable) accession number: Q5SQ80 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 27, 2006 |
Last sequence update: | December 21, 2004 | |
Last modified: | December 2, 2020 | |
This is version 119 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 9
Human chromosome 9: entries, gene names and cross-references to MIM