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Entry version 112 (08 May 2019)
Sequence version 1 (21 Dec 2004)
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Protein

Transmembrane protein 201

Gene

TMEM201

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in nuclear movement during fibroblast polarization and migration. Proposed to be involved in actin-dependent nuclear movement via association with transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow (By similarity). Overexpression can recruit Ran GTPase to the nuclear periphery (PubMed:27541860).By similarity1 Publication
Isoform 2: May define a distinct membrane domain in the vicinity of the mitotic spindle (PubMed:19494128). Involved in the organization of the nuclear envelope implicating EMD, SUN1 and A-type lamina (PubMed:21610090).2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin filament binding Source: GO_Central
  • lamin binding Source: GO_Central

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 201
Alternative name(s):
Spindle-associated membrane protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM201
Synonyms:NET5, SAMP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:33719 TMEM201

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5SNT2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 213Nuclear1 PublicationAdd BLAST213
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei214 – 234HelicalSequence analysisAdd BLAST21
Topological domaini235 – 297Perinuclear spaceCuratedAdd BLAST63
Transmembranei298 – 318HelicalSequence analysisAdd BLAST21
Topological domaini319 – 322NuclearCurated4
Transmembranei323 – 343HelicalSequence analysisAdd BLAST21
Topological domaini344 – 356Perinuclear spaceCuratedAdd BLAST13
Transmembranei357 – 374HelicalSequence analysisAdd BLAST18
Topological domaini375 – 644NuclearCuratedAdd BLAST270
Transmembranei645 – 665HelicalSequence analysisAdd BLAST21
Topological domaini666Perinuclear spaceCurated1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi48C → A: Impairs organization of the nuclear envelope; abolishes its localization to the nuclear envelope; impairs localization of SUN1 and EMD to the nuclear envelope. 1 Publication1
Mutagenesisi121C → A: Abolishes localization to the nuclear envelopee; abolishes its localization to the nuclear envelope; impairs localization of SUN1 and EMD to the nuclear envelope. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
199953

Open Targets

More...
OpenTargetsi
ENSG00000188807

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162406359

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TMEM201

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74743441

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003171981 – 666Transmembrane protein 201Add BLAST666

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei441PhosphoserineCombined sources1
Modified residuei444PhosphoserineCombined sources1
Modified residuei450PhosphoserineCombined sources1
Modified residuei454PhosphoserineCombined sources1
Modified residuei466PhosphoserineCombined sources1
Modified residuei477PhosphoserineCombined sources1
Modified residuei480PhosphoserineCombined sources1
Modified residuei529PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5SNT2

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5SNT2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5SNT2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5SNT2

PeptideAtlas

More...
PeptideAtlasi
Q5SNT2

PRoteomics IDEntifications database

More...
PRIDEi
Q5SNT2

ProteomicsDB human proteome resource

More...
ProteomicsDBi
63760
63761 [Q5SNT2-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5SNT2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5SNT2

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q5SNT2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000188807 Expressed in 177 organ(s), highest expression level in quadriceps femoris

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5SNT2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5SNT2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB039039

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Isoform 2 interacts with EMD (PubMed:21610090). Interacts with SUN2 and LMNA (By similarity). May bind to Ran GTPase; has a greater affinity for Ran-GTP over Ran-GDP.By similarity1 Publication1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
EMDP504023EBI-11994282,EBI-489887

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
128285, 14 interactors

Protein interaction database and analysis system

More...
IntActi
Q5SNT2, 23 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000344503

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5SNT2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi441 – 520Ser-richAdd BLAST80

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TMEM201 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4623 Eukaryota
ENOG41123RR LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000002713

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154619

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5SNT2

Identification of Orthologs from Complete Genome Data

More...
OMAi
QSHQMGV

Database of Orthologous Groups

More...
OrthoDBi
532133at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5SNT2

TreeFam database of animal gene trees

More...
TreeFami
TF106107

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018617 Ima1_N
IPR040041 TMEM201
IPR018861 TMEM201_C

The PANTHER Classification System

More...
PANTHERi
PTHR28646 PTHR28646, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10476 DUF2448, 1 hit
PF09779 Ima1_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5SNT2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEGVSALLAR CPTAGLAGGL GVTACAAAGV LLYRIARRMK PTHTMVNCWF
60 70 80 90 100
CNQDTLVPYG NRNCWDCPHC EQYNGFQENG DYNKPIPAQY LEHLNHVVSS
110 120 130 140 150
APSLRDPSQP QQWVSSQVLL CKRCNHHQTT KIKQLAAFAP REEGRYDEEV
160 170 180 190 200
EVYRHHLEQM YKLCRPCQAA VEYYIKHQNR QLRALLLSHQ FKRREADQTH
210 220 230 240 250
AQNFSSAVKS PVQVILLRAL AFLACAFLLT TALYGASGHF APGTTVPLAL
260 270 280 290 300
PPGGNGSATP DNGTTPGAEG WRQLLGLLPE HMAEKLCEAW AFGQSHQTGV
310 320 330 340 350
VALGLLTCLL AMLLAGRIRL RRIDAFCTCL WALLLGLHLA EQHLQAASPS
360 370 380 390 400
WLDTLKFSTT SLCCLVGFTA AVATRKATGP RRFRPRRFFP GDSAGLFPTS
410 420 430 440 450
PSLAIPHPSV GGSPASLFIP SPPSFLPLAN QQLFRSPRRT SPSSLPGRLS
460 470 480 490 500
RALSLGTIPS LTRADSGYLF SGSRPPSQVS RSGEFPVSDY FSLLSGSCPS
510 520 530 540 550
SPLPSPAPSV AGSVASSSGS LRHRRPLISP ARLNLKGQKL LLFPSPPGEA
560 570 580 590 600
PTTPSSSDEH SPHNGSLFTM EPPHVPRKPP LQDVKHALDL RSKLERGSAC
610 620 630 640 650
SNRSIKKEDD SSQSSTCVVD TTTRGCSEEA ATWRGRFGPS LVRGLLAVSL
660
AANALFTSVF LYQSLR
Length:666
Mass (Da):72,236
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i19A4E0F866838525
GO
Isoform 2 (identifier: Q5SNT2-2) [UniParc]FASTAAdd to basket
Also known as: SAMP1

The sequence of this isoform differs from the canonical sequence as follows:
     388-392: FFPGD → SEKQP
     393-666: Missing.

Show »
Length:392
Mass (Da):43,382
Checksum:i12392DC351F26F8A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y4R5H0Y4R5_HUMAN
Transmembrane protein 201
TMEM201
552Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y994H0Y994_HUMAN
Transmembrane protein 201
TMEM201
166Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_030915388 – 392FFPGD → SEKQP in isoform 2. 1 Publication5
Alternative sequenceiVSP_030916393 – 666Missing in isoform 2. 1 PublicationAdd BLAST274

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL954705 Genomic DNA No translation available.
BC121187 mRNA Translation: AAI21188.1
BC137291 mRNA Translation: AAI37292.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30579.1 [Q5SNT2-2]
CCDS44055.2 [Q5SNT2-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001010866.1, NM_001010866.3 [Q5SNT2-2]
NP_001124396.2, NM_001130924.2 [Q5SNT2-1]
XP_011539212.1, XM_011540910.2 [Q5SNT2-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000340305; ENSP00000344772; ENSG00000188807 [Q5SNT2-2]
ENST00000340381; ENSP00000344503; ENSG00000188807 [Q5SNT2-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
199953

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:199953

UCSC genome browser

More...
UCSCi
uc001apy.4 human [Q5SNT2-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL954705 Genomic DNA No translation available.
BC121187 mRNA Translation: AAI21188.1
BC137291 mRNA Translation: AAI37292.1
CCDSiCCDS30579.1 [Q5SNT2-2]
CCDS44055.2 [Q5SNT2-1]
RefSeqiNP_001010866.1, NM_001010866.3 [Q5SNT2-2]
NP_001124396.2, NM_001130924.2 [Q5SNT2-1]
XP_011539212.1, XM_011540910.2 [Q5SNT2-2]

3D structure databases

SMRiQ5SNT2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi128285, 14 interactors
IntActiQ5SNT2, 23 interactors
STRINGi9606.ENSP00000344503

PTM databases

iPTMnetiQ5SNT2
PhosphoSitePlusiQ5SNT2
SwissPalmiQ5SNT2

Polymorphism and mutation databases

BioMutaiTMEM201
DMDMi74743441

Proteomic databases

EPDiQ5SNT2
jPOSTiQ5SNT2
MaxQBiQ5SNT2
PaxDbiQ5SNT2
PeptideAtlasiQ5SNT2
PRIDEiQ5SNT2
ProteomicsDBi63760
63761 [Q5SNT2-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000340305; ENSP00000344772; ENSG00000188807 [Q5SNT2-2]
ENST00000340381; ENSP00000344503; ENSG00000188807 [Q5SNT2-1]
GeneIDi199953
KEGGihsa:199953
UCSCiuc001apy.4 human [Q5SNT2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
199953
DisGeNETi199953

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TMEM201
HGNCiHGNC:33719 TMEM201
HPAiCAB039039
neXtProtiNX_Q5SNT2
OpenTargetsiENSG00000188807
PharmGKBiPA162406359

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4623 Eukaryota
ENOG41123RR LUCA
GeneTreeiENSGT00390000002713
HOGENOMiHOG000154619
InParanoidiQ5SNT2
OMAiQSHQMGV
OrthoDBi532133at2759
PhylomeDBiQ5SNT2
TreeFamiTF106107

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TMEM201 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
199953

Protein Ontology

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PROi
PR:Q5SNT2

Gene expression databases

BgeeiENSG00000188807 Expressed in 177 organ(s), highest expression level in quadriceps femoris
ExpressionAtlasiQ5SNT2 baseline and differential
GenevisibleiQ5SNT2 HS

Family and domain databases

InterProiView protein in InterPro
IPR018617 Ima1_N
IPR040041 TMEM201
IPR018861 TMEM201_C
PANTHERiPTHR28646 PTHR28646, 1 hit
PfamiView protein in Pfam
PF10476 DUF2448, 1 hit
PF09779 Ima1_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTM201_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5SNT2
Secondary accession number(s): B9EH90, Q5SNT3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: December 21, 2004
Last modified: May 8, 2019
This is version 112 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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