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Protein

Glycogen synthase

Gene

glgA

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei15ADP-glucoseUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processGlycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164

Protein family/group databases

CAZyiGT5 Glycosyltransferase Family 5

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:TTHA0018
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002302681 – 437Glycogen synthaseAdd BLAST437

Interactioni

Protein-protein interaction databases

STRINGi300852.TTHA0018

Structurei

3D structure databases

ProteinModelPortaliQ5SMC5
SMRiQ5SMC5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CXW Bacteria
COG0297 LUCA
HOGENOMiHOG000294941
KOiK00703
OMAiTWCPWYM

Family and domain databases

HAMAPiMF_00484 Glycogen_synth, 1 hit
InterProiView protein in InterPro
IPR001296 Glyco_trans_1
IPR011835 GS/SS
IPR013534 Starch_synth_cat_dom
PfamiView protein in Pfam
PF08323 Glyco_transf_5, 1 hit
PF00534 Glycos_transf_1, 1 hit
TIGRFAMsiTIGR02095 glgA, 1 hit

Sequencei

Sequence statusi: Complete.

Q5SMC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVLHVAPEA YPLAKVGGLA DVVGALPKAL RPLGVEAHVL LPWHGGLEAR
60 70 80 90 100
RVGEVAFAFF GREERAPLGE RVEGGVRFLL LGVEGFGRER VYGYPDDAER
110 120 130 140 150
YLRFALAAKE VARGYDLVHA HDWTAALLAL YAPTVYTIHN LAHQGLVDPG
160 170 180 190 200
LFFSWTGLPW SLFHMEALEF YGRVNLMKGG IVFARRVTTV SPSYAEEIQT
210 220 230 240 250
PEFGMGLDGV LRRHAGKLRG ILNGLDTEVF DPGKDPYLPA PYTREDPSGK
260 270 280 290 300
ARAKEAFRER TGLRPPVLAY VGRLDYQKGL DLVLKALPRL LEMGFRLYVQ
310 320 330 340 350
GVGDGGLQEA FLRAEEENPE GVRFLPAYDE AMARLAYAGA EAVLVPSRFE
360 370 380 390 400
PCGLVQMIAS RYGTPPVARA VGGLKDTVED GRGGVLFETY HPEGLLYGVL
410 420 430
RLFRLGAEEM GLRAMEKDFS WEGPARAYRE VYREALG
Length:437
Mass (Da):48,259
Last modified:April 4, 2006 - v2
Checksum:i255F032F2EE26452
GO

Sequence cautioni

The sequence BAD69841 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA Translation: BAD69841.1 Different initiation.
RefSeqiYP_143284.1, NC_006461.1

Genome annotation databases

EnsemblBacteriaiBAD69841; BAD69841; BAD69841
GeneIDi3169395
KEGGittj:TTHA0018
PATRICifig|300852.9.peg.19

Similar proteinsi

Entry informationi

Entry nameiGLGA_THET8
AccessioniPrimary (citable) accession number: Q5SMC5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 4, 2006
Last modified: November 22, 2017
This is version 86 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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