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Protein

30S ribosomal protein S5

Gene

rpsE

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

With S4 and S12 plays an important role in translational accuracy.By similarity
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Binds mRNA in the 70S ribosome, positioning it for translation.

Miscellaneous

Is positioned such that it could physically interact with spectinomycin.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciTTHE300852:G1GKC-1681-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S5
Gene namesi
Name:rpsE
Ordered Locus Names:TTHA1675
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Chemistry databases

DrugBankiDB08185 2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001316212 – 16230S ribosomal protein S5Add BLAST161

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.

Protein-protein interaction databases

STRINGi300852.TTHA1675

Structurei

Secondary structure

1162
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi7 – 20Combined sources14
Beta strandi23 – 35Combined sources13
Beta strandi37 – 50Combined sources14
Helixi51 – 62Combined sources12
Beta strandi65 – 68Combined sources4
Beta strandi72 – 75Combined sources4
Beta strandi80 – 84Combined sources5
Beta strandi87 – 93Combined sources7
Beta strandi96 – 98Combined sources3
Beta strandi100 – 102Combined sources3
Helixi104 – 111Combined sources8
Turni112 – 114Combined sources3
Beta strandi117 – 124Combined sources8
Helixi128 – 141Combined sources14
Helixi145 – 151Combined sources7
Helixi154 – 156Combined sources3
Turni157 – 159Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FJGX-ray3.00E1-162[»]
1FKAX-ray3.30E1-162[»]
1HNWX-ray3.40E1-162[»]
1HNXX-ray3.40E1-162[»]
1HNZX-ray3.30E1-162[»]
1HR0X-ray3.20E1-162[»]
1I94X-ray3.20E2-162[»]
1I95X-ray4.50E2-162[»]
1I96X-ray4.20E2-162[»]
1I97X-ray4.50E2-162[»]
1IBKX-ray3.31E1-162[»]
1IBLX-ray3.11E1-162[»]
1IBMX-ray3.31E1-162[»]
1J5EX-ray3.05E2-162[»]
1JGOX-ray5.60H1-162[»]
1JGPX-ray7.00H1-162[»]
1JGQX-ray5.00H1-162[»]
1L1Umodel-E5-154[»]
1ML5electron microscopy14.00H1-162[»]
1N32X-ray3.00E2-162[»]
1N33X-ray3.35E2-162[»]
1N34X-ray3.80E2-162[»]
1N36X-ray3.65E2-162[»]
1QD7X-ray5.50D22-130[»]
1VVJX-ray3.44QE/XE1-162[»]
1VY4X-ray2.60AE/CE1-162[»]
1VY5X-ray2.55AE/CE1-162[»]
1VY6X-ray2.90AE/CE1-162[»]
1VY7X-ray2.80AE/CE1-162[»]
1XMOX-ray3.25E1-162[»]
1XMQX-ray3.00E1-162[»]
1XNQX-ray3.05E1-162[»]
1XNRX-ray3.10E1-162[»]
2E5LX-ray3.30E2-162[»]
2F4VX-ray3.80E1-162[»]
2HHHX-ray3.35E1-162[»]
2UU9X-ray3.10E2-162[»]
2UUAX-ray2.90E2-162[»]
2UUBX-ray2.80E2-162[»]
2UUCX-ray3.10E2-162[»]
2UXBX-ray3.10E2-162[»]
2UXCX-ray2.90E2-162[»]
2UXDX-ray3.20E2-162[»]
2VQEX-ray2.50E1-162[»]
2VQFX-ray2.90E1-162[»]
2ZM6X-ray3.30E2-162[»]
3OTOX-ray3.69E1-162[»]
3T1HX-ray3.11E1-162[»]
3T1YX-ray2.80E1-162[»]
4AQYX-ray3.50E2-162[»]
4B3MX-ray2.90E2-162[»]
4B3RX-ray3.00E2-162[»]
4B3SX-ray3.15E2-162[»]
4B3TX-ray3.00E2-162[»]
4DR1X-ray3.60E1-162[»]
4DR2X-ray3.25E1-162[»]
4DR3X-ray3.35E1-162[»]
4DR4X-ray3.97E1-162[»]
4DR5X-ray3.45E1-162[»]
4DR6X-ray3.30E1-162[»]
4DR7X-ray3.75E1-162[»]
4DUYX-ray3.39E1-162[»]
4DUZX-ray3.65E1-162[»]
4DV0X-ray3.85E1-162[»]
4DV1X-ray3.85E1-162[»]
4DV2X-ray3.65E1-162[»]
4DV3X-ray3.55E1-162[»]
4DV4X-ray3.65E1-162[»]
4DV5X-ray3.68E1-162[»]
4DV6X-ray3.30E1-162[»]
4DV7X-ray3.29E1-162[»]
4GKJX-ray3.30E5-154[»]
4GKKX-ray3.20E5-154[»]
4JI0X-ray3.49E1-162[»]
4JI1X-ray3.14E1-162[»]
4JI2X-ray3.64E1-162[»]
4JI3X-ray3.35E1-162[»]
4JI4X-ray3.69E1-162[»]
4JI5X-ray3.85E1-162[»]
4JI6X-ray3.55E1-162[»]
4JI7X-ray3.50E1-162[»]
4JI8X-ray3.74E1-162[»]
4JV5X-ray3.16E5-154[»]
4JYAX-ray3.10E5-154[»]
4K0KX-ray3.40E5-155[»]
4KHPX-ray3.10E5-154[»]
4L47X-ray3.22QE/XE1-162[»]
4L71X-ray3.90QE/XE1-162[»]
4LELX-ray3.90QE/XE1-162[»]
4LF4X-ray3.34E1-162[»]
4LF5X-ray3.75E1-162[»]
4LF6X-ray3.31E1-162[»]
4LF7X-ray3.15E1-162[»]
4LF8X-ray3.15E1-162[»]
4LF9X-ray3.28E1-162[»]
4LFAX-ray3.65E1-162[»]
4LFBX-ray3.01E1-162[»]
4LFCX-ray3.60E1-162[»]
4LFZX-ray3.92QE/XE1-162[»]
4LNTX-ray2.94QE/XE1-162[»]
4LSKX-ray3.48QE/XE1-162[»]
4LT8X-ray3.14QE/XE1-162[»]
4NXMX-ray3.65E1-162[»]
4NXNX-ray3.54E1-162[»]
4OX9X-ray3.80E2-162[»]
4P6FX-ray3.60QE/XE1-162[»]
4P70X-ray3.68QE/XE1-162[»]
4TUAX-ray3.60QE/XE1-162[»]
4TUBX-ray3.60QE/XE1-162[»]
4TUCX-ray3.60QE/XE1-162[»]
4TUDX-ray3.60QE/XE1-162[»]
4TUEX-ray3.50QE/XE1-162[»]
4V42X-ray5.50AH1-162[»]
4V49X-ray8.70E5-154[»]
4V4AX-ray9.50E5-154[»]
4V4GX-ray11.50E5-154[»]
4V4IX-ray3.71f-[»]
4V4PX-ray5.50BH1-162[»]
4V4RX-ray5.90AE1-162[»]
4V4SX-ray6.76AE1-162[»]
4V4TX-ray6.46AE1-162[»]
4V4XX-ray5.00AH1-162[»]
4V4YX-ray5.50AH1-162[»]
4V4ZX-ray4.51AH1-162[»]
4V51X-ray2.80AE/CE2-162[»]
4V5AX-ray3.50AE/CE2-162[»]
4V5CX-ray3.30AE/CE1-162[»]
4V5DX-ray3.50AE/CE1-162[»]
4V5EX-ray3.45AE/CE1-162[»]
4V5FX-ray3.60AE/CE1-162[»]
4V5GX-ray3.60AE/CE1-162[»]
4V5JX-ray3.10AE/CE1-162[»]
4V5KX-ray3.20AE/CE1-162[»]
4V5LX-ray3.10AE1-162[»]
4V5Melectron microscopy7.80AE1-162[»]
4V5Nelectron microscopy7.60AE1-162[»]
4V5PX-ray3.10AE/CE1-162[»]
4V5QX-ray3.10AE/CE1-162[»]
4V5RX-ray3.10AE/CE1-162[»]
4V5SX-ray3.10AE/CE1-162[»]
4V68electron microscopy6.40AE5-155[»]
4V6AX-ray3.10AE/CE1-162[»]
4V6FX-ray3.10BH/CH1-162[»]
4V6GX-ray3.50AH/CH1-162[»]
4V7JX-ray3.30Ae/Be1-162[»]
4V7KX-ray3.60Ae/Be1-162[»]
4V7LX-ray3.00AE/CE1-162[»]
4V7MX-ray3.45AE/CE1-162[»]
4V7WX-ray3.00AE/CE1-162[»]
4V7XX-ray3.00AE/CE1-160[»]
4V7YX-ray3.00AE/CE1-162[»]
4V7ZX-ray3.10AE/CE1-162[»]
4V87X-ray3.10BH/CH1-162[»]
4V8AX-ray3.20CE/DE1-162[»]
4V8BX-ray3.00AH/CH1-162[»]
4V8CX-ray3.30CH/DH1-162[»]
4V8DX-ray3.00AH/CH1-162[»]
4V8EX-ray3.30BH/DH1-162[»]
4V8FX-ray3.30BH/CH1-162[»]
4V8GX-ray3.00AE/CE1-162[»]
4V8HX-ray3.10AE/CE1-162[»]
4V8IX-ray2.70AE/CE1-162[»]
4V8JX-ray3.90AE/CE1-162[»]
4V8NX-ray3.10AE/CE1-162[»]
4V8OX-ray3.80AE1-162[»]
4V8QX-ray3.10BE1-162[»]
4V8UX-ray3.70AE/CE1-162[»]
4V8XX-ray3.35AE/CE1-162[»]
4V90X-ray2.95AE1-162[»]
4V95X-ray3.20AE/CE1-162[»]
4V97X-ray3.52AE/CE1-162[»]
4V9AX-ray3.30AH/CH1-162[»]
4V9BX-ray3.10AH/CH1-162[»]
4V9HX-ray2.86AE5-154[»]
4V9IX-ray3.30AE/CE5-154[»]
4V9RX-ray3.00AE/CE1-162[»]
4V9SX-ray3.10AE/CE1-162[»]
4W2EX-ray2.90e1-162[»]
4W2FX-ray2.40AE/CE1-162[»]
4W2GX-ray2.55AE/CE1-162[»]
4W2HX-ray2.70AE/CE1-162[»]
4W2IX-ray2.70AE/CE1-162[»]
4W4GX-ray3.30QE/XE1-162[»]
4WPOX-ray2.80BE/DE1-162[»]
4WQ1X-ray3.1042/4E1-162[»]
4WQFX-ray2.80BE/DE1-162[»]
4WQRX-ray3.1542/4E1-162[»]
4WQUX-ray2.80BE/DE1-162[»]
4WQYX-ray2.80BE/DE1-162[»]
4WR6X-ray3.0542/4E1-162[»]
4WRAX-ray3.0542/4E1-162[»]
4WROX-ray3.054E1-162[»]
4WSDX-ray2.9542/4E1-162[»]
4WSMX-ray3.3042/4E1-162[»]
4WT1X-ray3.0542/4E1-162[»]
4WT8X-ray3.40AE/BE5-154[»]
4WU1X-ray3.2042/4E1-162[»]
4WZDX-ray3.1042/4E1-162[»]
4WZOX-ray3.3042/4E1-162[»]
4X62X-ray3.45E5-155[»]
4X64X-ray3.35E5-155[»]
4X65X-ray3.35E5-155[»]
4X66X-ray3.45E5-155[»]
4Y4OX-ray2.301e/2e1-162[»]
4Y4PX-ray2.501e/2e1-162[»]
4YHHX-ray3.42E5-161[»]
4YPBX-ray3.40QE/XE1-162[»]
4YY3X-ray3.60E1-162[»]
4YZVX-ray3.10QE/XE1-162[»]
4Z3SX-ray2.651e/2e1-162[»]
4Z8CX-ray2.901e/2e1-162[»]
4ZERX-ray3.101e/2e5-152[»]
4ZSNX-ray3.60QE/XE1-162[»]
5A9Zelectron microscopy4.70BI5-154[»]
5AA0electron microscopy5.00BI5-154[»]
5BR8X-ray3.40E1-162[»]
5CZPX-ray3.30QE/XE1-162[»]
5D8BX-ray3.63BC/FA1-162[»]
5DFEX-ray3.10QE/XE1-162[»]
5DOXX-ray3.101e/2e1-162[»]
5DOYX-ray2.601e/2e1-162[»]
5E7KX-ray3.2042/4E1-162[»]
5E81X-ray2.9542/4E1-162[»]
5EL4X-ray3.1542/4E1-162[»]
5EL5X-ray3.1542/4E1-162[»]
5EL6X-ray3.1042/4E1-162[»]
5EL7X-ray3.1542/4E1-162[»]
5F8KX-ray2.801e/2e5-152[»]
5FDUX-ray2.901e/2e5-152[»]
5FDVX-ray2.801e/2e5-152[»]
5HAUX-ray3.001e/2e1-162[»]
5HCPX-ray2.891e/2e1-162[»]
5HCQX-ray2.801e/2e1-162[»]
5HCRX-ray2.801e/2e1-162[»]
5HD1X-ray2.701e/2e1-162[»]
5IB7X-ray2.9942/4E1-162[»]
5IB8X-ray3.1342/4E1-162[»]
5IBBX-ray2.9642/4E1-162[»]
5IMQelectron microscopy3.80I1-162[»]
5IMRelectron microscopy-I1-162[»]
5IWAX-ray3.50E5-161[»]
5J30X-ray3.20QE/XE1-162[»]
5J3CX-ray3.04QE/XE1-162[»]
5J4BX-ray2.601e/2e1-162[»]
5J4CX-ray2.801e/2e1-162[»]
5J8BX-ray2.60e1-162[»]
5LMNelectron microscopy3.55E1-162[»]
5LMOelectron microscopy4.30E1-162[»]
5LMPelectron microscopy5.35E1-162[»]
5LMQelectron microscopy4.20E1-162[»]
5LMRelectron microscopy4.45E1-162[»]
5LMSelectron microscopy5.10E1-162[»]
5LMTelectron microscopy4.15E1-162[»]
5LMUelectron microscopy4.00E1-162[»]
5LMVelectron microscopy4.90E1-162[»]
5NDJX-ray3.1542/4E1-162[»]
5NDKX-ray2.9542/4E1-162[»]
5OT7electron microscopy3.80D5-155[»]
5UQ7electron microscopy3.50e5-152[»]
5UQ8electron microscopy3.20e5-152[»]
5VP2X-ray2.801e/2e1-162[»]
5W4KX-ray2.701e/2e1-162[»]
5WISX-ray2.701e/2e1-162[»]
5WITX-ray2.601e/2e1-162[»]
5WNPX-ray3.30E5-155[»]
5WNQX-ray3.50E5-154[»]
5WNRX-ray3.50E5-154[»]
5WNSX-ray3.50E5-154[»]
5WNTX-ray3.30E5-155[»]
5WNUX-ray3.40E5-155[»]
5WNVX-ray3.30E5-155[»]
6C5LX-ray3.20AE/CE1-162[»]
6CAEX-ray2.601e/2e1-162[»]
6CFJX-ray2.801e/2e1-162[»]
6CFKX-ray2.701e/2e1-162[»]
6CFLX-ray2.601e/2e1-162[»]
6FKRX-ray3.201e/2e5-152[»]
ProteinModelPortaliQ5SHQ5
SMRiQ5SHQ5
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5SHQ5

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 69S5 DRBMAdd BLAST64

Domaini

The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4108RA9 Bacteria
COG0098 LUCA
HOGENOMiHOG000072595
KOiK02988
OMAiKRGCGSW
PhylomeDBiQ5SHQ5

Family and domain databases

Gene3Di3.30.230.10, 1 hit
HAMAPiMF_01307_B Ribosomal_S5_B, 1 hit
InterProiView protein in InterPro
IPR000851 Ribosomal_S5
IPR005712 Ribosomal_S5_bac-type
IPR005324 Ribosomal_S5_C
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR013810 Ribosomal_S5_N
IPR018192 Ribosomal_S5_N_CS
PANTHERiPTHR13718 PTHR13718, 1 hit
PfamiView protein in Pfam
PF00333 Ribosomal_S5, 1 hit
PF03719 Ribosomal_S5_C, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
TIGRFAMsiTIGR01021 rpsE_bact, 1 hit
PROSITEiView protein in PROSITE
PS00585 RIBOSOMAL_S5, 1 hit
PS50881 S5_DSRBD, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5SHQ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPETDFEEKM ILIRRTARMQ AGGRRFRFGA LVVVGDRQGR VGLGFGKAPE
60 70 80 90 100
VPLAVQKAGY YARRNMVEVP LQNGTIPHEI EVEFGASKIV LKPAAPGTGV
110 120 130 140 150
IAGAVPRAIL ELAGVTDILT KELGSRNPIN IAYATMEALR QLRTKADVER
160
LRKGEAHAQA QG
Length:162
Mass (Da):17,557
Last modified:January 23, 2007 - v3
Checksum:iBE3367CB619E68D2
GO

Mass spectrometryi

Molecular mass is 17428 Da from positions 2 - 162. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA Translation: BAD71498.1
RefSeqiWP_008633389.1, NC_006461.1
YP_144941.1, NC_006461.1

Genome annotation databases

EnsemblBacteriaiBAD71498; BAD71498; BAD71498
GeneIDi3169827
KEGGittj:TTHA1675
PATRICifig|300852.9.peg.1645

Similar proteinsi

Entry informationi

Entry nameiRS5_THET8
AccessioniPrimary (citable) accession number: Q5SHQ5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: January 23, 2007
Last modified: June 20, 2018
This is version 129 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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