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Protein

50S ribosomal protein L18

Gene

rplR

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This is one of the proteins that binds and mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciTTHE300852:G1GKC-1682-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L18
Alternative name(s):
TL24
Gene namesi
Name:rplR
Ordered Locus Names:TTHA1676
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved3 Publications
ChainiPRO_00001313722 – 11250S ribosomal protein L18Add BLAST111

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and probably the 23S rRNA; has been isolated in a complex with the 5S rRNA and RL25 (Ref. 2).

Protein-protein interaction databases

STRINGi300852.TTHA1676

Structurei

Secondary structure

1112
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi16 – 19Combined sources4
Beta strandi25 – 30Combined sources6
Beta strandi35 – 41Combined sources7
Turni42 – 45Combined sources4
Beta strandi46 – 51Combined sources6
Helixi54 – 56Combined sources3
Helixi63 – 79Combined sources17
Beta strandi102 – 104Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1VVJX-ray3.44RS/YS1-112[»]
1VY4X-ray2.60BS/DS1-112[»]
1VY5X-ray2.55BS/DS1-112[»]
1VY6X-ray2.90BS/DS1-112[»]
1VY7X-ray2.80BS/DS1-112[»]
4L47X-ray3.22RS/YS1-112[»]
4L71X-ray3.90RS/YS1-112[»]
4LELX-ray3.90RS/YS1-112[»]
4LFZX-ray3.92RS/YS1-112[»]
4LNTX-ray2.94RS/YS1-112[»]
4LSKX-ray3.48RS/YS1-112[»]
4LT8X-ray3.14RS/YS1-112[»]
4P6FX-ray3.60RS/YS1-112[»]
4P70X-ray3.68RS/YS1-112[»]
4TUAX-ray3.60RS/YS1-112[»]
4TUBX-ray3.60RS/YS1-112[»]
4TUCX-ray3.60RS/YS1-112[»]
4TUDX-ray3.60RS/YS1-112[»]
4TUEX-ray3.50RS/YS1-112[»]
4V42X-ray5.50BQ1-112[»]
4V4PX-ray5.50Q1-112[»]
4V4XX-ray5.00BR1-112[»]
4V4YX-ray5.50BR1-112[»]
4V4ZX-ray4.51BR1-112[»]
4V51X-ray2.80BS/DS2-112[»]
4V5AX-ray3.50BS/DS2-112[»]
4V5CX-ray3.30BS/DS1-112[»]
4V5DX-ray3.50BS/DS1-112[»]
4V5EX-ray3.45BS/DS1-112[»]
4V5FX-ray3.60BS/DS1-112[»]
4V5GX-ray3.60BS/DS1-112[»]
4V5JX-ray3.10BS/DS1-112[»]
4V5KX-ray3.20BS/DS1-112[»]
4V5LX-ray3.10BS1-112[»]
4V5Melectron microscopy7.80BS1-112[»]
4V5Nelectron microscopy7.60BS1-112[»]
4V5PX-ray3.10BS/DS1-112[»]
4V5QX-ray3.10BS/DS1-112[»]
4V5RX-ray3.10BS/DS1-112[»]
4V5SX-ray3.10BS/DS1-112[»]
4V68electron microscopy6.40BS11-109[»]
4V6AX-ray3.10BS/DS1-112[»]
4V6FX-ray3.10AQ/DQ1-112[»]
4V6GX-ray3.50BQ/DQ1-112[»]
4V7JX-ray3.30AS/BS1-112[»]
4V7KX-ray3.60AS/BS1-112[»]
4V7LX-ray3.00BS/DS1-112[»]
4V7MX-ray3.45BS/DS1-112[»]
4V7WX-ray3.00BS/DS1-112[»]
4V7XX-ray3.00BS/DS1-112[»]
4V7YX-ray3.00BS/DS1-112[»]
4V7ZX-ray3.10BS/DS1-112[»]
4V87X-ray3.10AQ/DQ2-112[»]
4V8AX-ray3.20AS/BS1-112[»]
4V8BX-ray3.00BQ/DQ1-112[»]
4V8CX-ray3.30AQ/BQ1-112[»]
4V8DX-ray3.00BQ/DQ1-112[»]
4V8EX-ray3.30AQ/CQ1-112[»]
4V8FX-ray3.30AQ/DQ1-112[»]
4V8GX-ray3.00BS/DS1-112[»]
4V8HX-ray3.10BS/DS1-112[»]
4V8IX-ray2.70BS/DS1-112[»]
4V8JX-ray3.90BS/DS1-112[»]
4V8NX-ray3.10BS/DS1-112[»]
4V8OX-ray3.80BS1-112[»]
4V8QX-ray3.10AS1-112[»]
4V8UX-ray3.70BS/DS1-112[»]
4V8XX-ray3.35BS/DS1-112[»]
4V90X-ray2.95BS2-112[»]
4V95X-ray3.20BS/DS1-112[»]
4V97X-ray3.52BS/DS1-112[»]
4V9AX-ray3.30BQ/DQ1-112[»]
4V9BX-ray3.10BQ/DQ1-112[»]
4V9HX-ray2.86BS1-112[»]
4V9IX-ray3.30BS/DS11-108[»]
4V9RX-ray3.00BS/DS1-112[»]
4V9SX-ray3.10BS/DS1-112[»]
4W2EX-ray2.90S1-112[»]
4W2FX-ray2.40BS/DS1-112[»]
4W2GX-ray2.55BS/DS1-112[»]
4W2HX-ray2.70BS/DS1-112[»]
4W2IX-ray2.70BS/DS1-112[»]
4W4GX-ray3.30RS/YS1-112[»]
4WPOX-ray2.80AS/CS1-112[»]
4WQ1X-ray3.1065/A82-112[»]
4WQFX-ray2.80AS/CS1-112[»]
4WQRX-ray3.1565/A81-112[»]
4WQUX-ray2.80AS/CS1-112[»]
4WQYX-ray2.80AS/CS1-112[»]
4WR6X-ray3.0565/A81-112[»]
4WRAX-ray3.0565/A81-112[»]
4WROX-ray3.05A81-112[»]
4WSDX-ray2.9565/A81-112[»]
4WSMX-ray3.3065/A81-112[»]
4WT1X-ray3.0565/A81-112[»]
4WT8X-ray3.40CR/DR11-108[»]
4WU1X-ray3.2065/A81-112[»]
4WZDX-ray3.1065/A81-112[»]
4WZOX-ray3.3065/A81-112[»]
4Y4OX-ray2.301S/2S1-112[»]
4Y4PX-ray2.501S/2S1-112[»]
4YPBX-ray3.40RS/YS1-112[»]
4YZVX-ray3.10RS/YS1-112[»]
4Z3SX-ray2.651S/2S1-112[»]
4Z8CX-ray2.901S/2S1-112[»]
4ZERX-ray3.101S/2S3-112[»]
4ZSNX-ray3.60RS/YS1-112[»]
5A9Zelectron microscopy4.70AP3-112[»]
5AA0electron microscopy5.00AP3-112[»]
5CZPX-ray3.30RS/YS1-112[»]
5D8BX-ray3.63IB/M1-112[»]
5DFEX-ray3.10RS/YS1-112[»]
5DOXX-ray3.101S/2S1-112[»]
5DOYX-ray2.601S/2S1-112[»]
5E7KX-ray3.2065/A81-112[»]
5E81X-ray2.9565/A81-112[»]
5EL4X-ray3.1565/A81-112[»]
5EL5X-ray3.1565/A81-112[»]
5EL6X-ray3.1065/A81-112[»]
5EL7X-ray3.1565/A81-112[»]
5F8KX-ray2.801S/2S3-112[»]
5FDUX-ray2.901S/2S3-112[»]
5FDVX-ray2.801S/2S3-112[»]
5HAUX-ray3.001Q/2Q1-112[»]
5HCPX-ray2.891S/2S1-112[»]
5HCQX-ray2.801S/2S1-112[»]
5HCRX-ray2.801S/2S1-112[»]
5HD1X-ray2.701S/2S1-112[»]
5IB7X-ray2.9965/A81-112[»]
5IB8X-ray3.1365/A81-112[»]
5IBBX-ray2.9665/A81-112[»]
5IMQelectron microscopy3.80k1-112[»]
5IMRelectron microscopy-k1-112[»]
5J30X-ray3.20RS/YS1-112[»]
5J3CX-ray3.04RS/YS1-112[»]
5J4BX-ray2.601S/2S1-112[»]
5J4CX-ray2.801S/2S1-112[»]
5J8BX-ray2.60S1-112[»]
5NDJX-ray3.1565/A81-112[»]
5NDKX-ray2.9565/A81-112[»]
5OT7electron microscopy3.80t11-109[»]
5UQ7electron microscopy3.50S3-112[»]
5UQ8electron microscopy3.20S3-112[»]
5VP2X-ray2.801S/2S1-112[»]
5W4KX-ray2.701S/2S1-112[»]
5WISX-ray2.701S/2S1-112[»]
5WITX-ray2.601S/2S1-112[»]
6C5LX-ray3.20BS/DS1-112[»]
6CAEX-ray2.601S/2S1-112[»]
6CFJX-ray2.801S/2S1-112[»]
6CFKX-ray2.701S/2S1-112[»]
6FKRX-ray3.201S/2S3-112[»]
ProteinModelPortaliQ5SHQ4
SMRiQ5SHQ4
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5SHQ4

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105K4C Bacteria
COG0256 LUCA
HOGENOMiHOG000248742
KOiK02881
OMAiYHGRVKS
PhylomeDBiQ5SHQ4

Family and domain databases

HAMAPiMF_01337_B Ribosomal_L18_B, 1 hit
InterProiView protein in InterPro
IPR005484 Ribosomal_L18
IPR004389 Ribosomal_L18_bac-type
PANTHERiPTHR12899 PTHR12899, 1 hit
PfamiView protein in Pfam
PF00861 Ribosomal_L18p, 1 hit
TIGRFAMsiTIGR00060 L18_bact, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5SHQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARLTAYERR KFRVRNRIKR TGRLRLSVFR SLKHIYAQII DDEKGVTLVS
60 70 80 90 100
ASSLALKLKG NKTEVARQVG RALAEKALAL GIKQVAFDRG PYKYHGRVKA
110
LAEGAREGGL EF
Length:112
Mass (Da):12,612
Last modified:January 23, 2007 - v3
Checksum:iEA2AB016AEDB0638
GO

Mass spectrometryi

Molecular mass is 12481 Da from positions 2 - 112. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA Translation: BAD71499.1
RefSeqiWP_008633391.1, NC_006461.1
YP_144942.1, NC_006461.1

Genome annotation databases

EnsemblBacteriaiBAD71499; BAD71499; BAD71499
GeneIDi3169978
KEGGittj:TTHA1676
PATRICifig|300852.9.peg.1646

Similar proteinsi

Entry informationi

Entry nameiRL18_THET8
AccessioniPrimary (citable) accession number: Q5SHQ4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: January 23, 2007
Last modified: June 20, 2018
This is version 116 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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