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Protein

Alpha-1,4 glucan phosphorylase

Gene

pygl

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.UniRule annotation

Catalytic activityi

((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase
Biological processCarbohydrate metabolismUniRule annotation
LigandPyridoxal phosphateUniRule annotation

Protein family/group databases

CAZyiGT35 Glycosyltransferase Family 35

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-1,4 glucan phosphorylaseUniRule annotation (EC:2.4.1.1UniRule annotation)
Gene namesi
Name:pyglImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-041205-1 pygl

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei793N6-(pyridoxal phosphate)lysineUniRule annotation1

Proteomic databases

PRIDEiQ5RKM9

Structurei

3D structure databases

ProteinModelPortaliQ5RKM9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycogen phosphorylase family.UniRule annotation

Phylogenomic databases

KOiK00688
PhylomeDBiQ5RKM9

Family and domain databases

CDDicd04300 GT1_Glycogen_Phosphorylase, 1 hit
InterProiView protein in InterPro
IPR011833 Glycg_phsphrylas
IPR000811 Glyco_trans_35
IPR035090 Pyridoxal_P_attach_site
PANTHERiPTHR11468 PTHR11468, 3 hits
PfamiView protein in Pfam
PF00343 Phosphorylase, 2 hits
PIRSFiPIRSF000460 Pprylas_GlgP, 3 hits
TIGRFAMsiTIGR02093 P_ylase, 1 hit
PROSITEiView protein in PROSITE
PS00102 PHOSPHORYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q5RKM9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATPHTDQEK RKQISIRGIV GVENVAELKK GFNRHLHFTL VKDRNVATPR
60 70 80 90 100
DYYFALSHTV RDHLVGRWIR TQQFCYEADP KRVYYLSLEF YMGRTLQNTM
110 120 130 140 150
INLGLQNACD EAIYQLGLDM EDLEEMEEDA GLGNGGLGRL AACFLDSMAT
160 170 180 190 200
LGLAAYGYGI RYEYGIFNQK IKDGWQVEEA DDWSRYGNPW EKARPEFMLP
210 220 230 240 250
VHFYGRVEEE EGKEPKWVDT QVVLAMPYDT PIPGYMNNTV NTMRLWSARA
260 270 280 290 300
PNDFNLRDFN VGDYIQAVLD RNLAENISRV LYPNDNFFEG KELRLKQEYF
310 320 330 340 350
VVAATLQDVI RRFKTSKRNT SGPLSFDSFP DKVAIQLNDT HPAMAIPELM
360 370 380 390 400
RIFVDIEKLD WDTAWDITKR TFAYTNHTVL PEALERWPVD LMEKLLPRHL
410 420 430 440 450
QIIYKINLIH LNHIASLFPE DMDRIRRMSP IEEGGGKRVN MAHLCIVGSH
460 470 480 490 500
KVNGAACFLD SMATLGLAAY GYGIRYEYGI FNQKIKDGWQ VEEADDWLRY
510 520 530 540 550
GNPWEKARPE FMLPVHFYGR VEEEEGKEPK WVDTQVVLAM PYDTPIPGYM
560 570 580 590 600
NNTVNTMRLW SARAPNDFNL RDFNVGDYIQ AVLDRNLAEN ISRVLYPNDN
610 620 630 640 650
FFEGKELRLK QEYFVVAATL QDVIRRFKTS KRNTSGPLSF DSFPDKVAIQ
660 670 680 690 700
LNDTHPAMAI PELMRIFVDI EKLDWDTAWD ITKRTFAYTN HTVLPEALER
710 720 730 740 750
WPVDLMEKLL PRHLQIIYKI NLIHLNHMAK MIIKLITSVA DVVNNDPVIG
760 770 780 790 800
RKLKVIFLEN YRVSLAEKVI PATDLSEQIS TAGTEASGTG NMKFMLNGAL
810 820 830 840 850
TIGTMDGANV EMAEEAGEEN LFIFGMRVDD VAELDKKGYN ALQYYENLPE
860 870 880 890 900
LKRAINQIKS GYFSPKQPEM FSDIINMLFH HDRFKVFADY ESYVKCQDRV
910 920 930 940 950
SALYKDQREW TRVVIKNIAA SGKFSSDRTI TEYATEIWGV EPTDLKIPPP
960
GEPREALEET ARSLRKT
Length:967
Mass (Da):111,538
Last modified:December 21, 2004 - v1
Checksum:iB5E1470164E44140
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC085616 mRNA Translation: AAH85616.1
RefSeqiNP_001008538.1, NM_001008538.1
UniGeneiDr.37123

Genome annotation databases

GeneIDi493916
KEGGidre:493916

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC085616 mRNA Translation: AAH85616.1
RefSeqiNP_001008538.1, NM_001008538.1
UniGeneiDr.37123

3D structure databases

ProteinModelPortaliQ5RKM9
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGT35 Glycosyltransferase Family 35

Proteomic databases

PRIDEiQ5RKM9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi493916
KEGGidre:493916

Organism-specific databases

CTDi5836
ZFINiZDB-GENE-041205-1 pygl

Phylogenomic databases

KOiK00688
PhylomeDBiQ5RKM9

Family and domain databases

CDDicd04300 GT1_Glycogen_Phosphorylase, 1 hit
InterProiView protein in InterPro
IPR011833 Glycg_phsphrylas
IPR000811 Glyco_trans_35
IPR035090 Pyridoxal_P_attach_site
PANTHERiPTHR11468 PTHR11468, 3 hits
PfamiView protein in Pfam
PF00343 Phosphorylase, 2 hits
PIRSFiPIRSF000460 Pprylas_GlgP, 3 hits
TIGRFAMsiTIGR02093 P_ylase, 1 hit
PROSITEiView protein in PROSITE
PS00102 PHOSPHORYLASE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5RKM9_DANRE
AccessioniPrimary (citable) accession number: Q5RKM9
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: February 28, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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