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Protein

Platelet-derived growth factor receptor-like protein

Gene

Pdgfrl

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Platelet-derived growth factor receptor-like protein
Short name:
PDGFR-like protein
Gene namesi
Name:Pdgfrl
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 16

Organism-specific databases

RGDi1308028 Pdgfrl

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_000023309318 – 375Platelet-derived growth factor receptor-like proteinAdd BLAST358

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi96 ↔ 143PROSITE-ProRule annotation
Glycosylationi219N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi293 ↔ 357PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ5RJP7
PRIDEiQ5RJP7

Expressioni

Gene expression databases

BgeeiENSRNOG00000010832 Expressed in 9 organ(s), highest expression level in skeletal muscle tissue
GenevisibleiQ5RJP7 RN

Interactioni

Subunit structurei

Forms a complex composed of PDGFRL, TNK2 and GRB2.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000014623

Structurei

3D structure databases

ProteinModelPortaliQ5RJP7
SMRiQ5RJP7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 159Ig-like C2-type 1Add BLAST98
Domaini272 – 375Ig-like C2-type 2Add BLAST104

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal

Phylogenomic databases

eggNOGiKOG0200 Eukaryota
COG0515 LUCA
GeneTreeiENSGT00390000017153
HOGENOMiHOG000012984
HOVERGENiHBG053893
InParanoidiQ5RJP7
OMAiKGRFQKP
OrthoDBiEOG091G09SI
PhylomeDBiQ5RJP7

Family and domain databases

Gene3Di2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
SMARTiView protein in SMART
SM00409 IG, 2 hits
SUPFAMiSSF48726 SSF48726, 3 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 2 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5RJP7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKVWLLLGLL LLHEALGDVA GQHPPKNKRP KEQGENRIKP TNKKAKPKIP
60 70 80 90 100
KIKDRDTADS APKSQSIMMQ AMDNGRFQKP AATVSLMAGQ SVELRCKGSK
110 120 130 140 150
VEWSYPAYLD TFKDSRLTVK QNERYGQLTL VNSTTADTGE FSCWERLCNG
160 170 180 190 200
YICRRDEART GSTYIFFTEK GELFVPSPSY FDVVYLNPDR QAVVPCRVTA
210 220 230 240 250
PSAKVTLHRE FPAKEIPANG TDIVYDMKRG FVYLQPHSDH QGVVYCKAEA
260 270 280 290 300
GGKSQISVKY QLLYVEVPSG PPSTTILASS NKVRGGDDIS VLCTVLGEPD
310 320 330 340 350
VEVEFRWIFP GQKDERPVTI QDTWRLIHRG LGHTTRISQS VITVEDFETI
360 370
DAGYYICTAQ NLRGQTTVAT TVEFS
Length:375
Mass (Da):41,933
Last modified:December 21, 2004 - v1
Checksum:i349AA537222F2FD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086555 mRNA Translation: AAH86555.1
RefSeqiNP_001011921.1, NM_001011921.1
UniGeneiRn.217523

Genome annotation databases

EnsembliENSRNOT00000014623; ENSRNOP00000014623; ENSRNOG00000010832
GeneIDi290771
KEGGirno:290771

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086555 mRNA Translation: AAH86555.1
RefSeqiNP_001011921.1, NM_001011921.1
UniGeneiRn.217523

3D structure databases

ProteinModelPortaliQ5RJP7
SMRiQ5RJP7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000014623

Proteomic databases

PaxDbiQ5RJP7
PRIDEiQ5RJP7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000014623; ENSRNOP00000014623; ENSRNOG00000010832
GeneIDi290771
KEGGirno:290771

Organism-specific databases

CTDi5157
RGDi1308028 Pdgfrl

Phylogenomic databases

eggNOGiKOG0200 Eukaryota
COG0515 LUCA
GeneTreeiENSGT00390000017153
HOGENOMiHOG000012984
HOVERGENiHBG053893
InParanoidiQ5RJP7
OMAiKGRFQKP
OrthoDBiEOG091G09SI
PhylomeDBiQ5RJP7

Miscellaneous databases

PROiPR:Q5RJP7

Gene expression databases

BgeeiENSRNOG00000010832 Expressed in 9 organ(s), highest expression level in skeletal muscle tissue
GenevisibleiQ5RJP7 RN

Family and domain databases

Gene3Di2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
SMARTiView protein in SMART
SM00409 IG, 2 hits
SUPFAMiSSF48726 SSF48726, 3 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiPGFRL_RAT
AccessioniPrimary (citable) accession number: Q5RJP7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: December 21, 2004
Last modified: September 12, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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