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Entry version 96 (03 Jul 2019)
Sequence version 1 (21 Dec 2004)
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Protein

D-ribitol-5-phosphate cytidylyltransferase

Gene

Crppa

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cytidylyltransferase required for protein O-linked mannosylation (By similarity). Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate (By similarity). CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity). Shows activity toward other pentose phosphate sugars and mediates formation of CDP-ribulose or CDP-ribose using CTP and ribulose-5-phosphate or ribose-5-phosphate, respectively (By similarity). Not Involved in dolichol production (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.By similarity
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei57Transition state stabilizerBy similarity1
Sitei64Transition state stabilizerBy similarity1
Sitei203Positions substrate for the nucleophilic attackBy similarity1
Sitei261Positions substrate for the nucleophilic attackBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionNucleotidyltransferase, Transferase

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00378

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
D-ribitol-5-phosphate cytidylyltransferaseBy similarity (EC:2.7.7.40By similarity)
Alternative name(s):
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like proteinBy similarity
Isoprenoid synthase domain-containing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Crppa
Synonyms:IspdImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1923097 Crppa

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003436981 – 447D-ribitol-5-phosphate cytidylyltransferaseAdd BLAST447

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5RJG7

PRoteomics IDEntifications database

More...
PRIDEi
Q5RJG7

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5RJG7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000043153 Expressed in 150 organ(s), highest expression level in lumbar subsegment of spinal cord

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5RJG7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5RJG7 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q5RJG7, 1 interactor

Molecular INTeraction database

More...
MINTi
Q5RJG7

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000061646

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5RJG7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIH2 Eukaryota
COG1211 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000006412

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5RJG7

KEGG Orthology (KO)

More...
KOi
K21031

Identification of Orthologs from Complete Genome Data

More...
OMAi
ERQHSVY

Database of Orthologous Groups

More...
OrthoDBi
1356473at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5RJG7

TreeFam database of animal gene trees

More...
TreeFami
TF328415

Family and domain databases

Conserved Domains Database

More...
CDDi
cd02516 CDP-ME_synthetase, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.90.550.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR034683 IspD/TarI
IPR040635 ISPD_C
IPR018294 ISPD_synthase_CS
IPR029044 Nucleotide-diphossugar_trans

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01128 IspD, 1 hit
PF18706 ISPD_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53448 SSF53448, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01295 ISPD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5RJG7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEPGPCSRPA EPGHCVSGPA GAGSAFPESP LSVAGAEPGN RPGTVAAVLP
60 70 80 90 100
AGGCGERMGV RTPKQFCRVL ERPLISYTLQ AMERVCWIKD IVVTVTGENM
110 120 130 140 150
EAMRSIIQRY GHKRISLAEA GATRHRSIFN GLKALAEDQP DCKLTKPEVV
160 170 180 190 200
IIHDAVRPFV EEDILLRVVL AAKEHGAAGA IRPLVSTVIS PSADGHLDHS
210 220 230 240 250
LDRAKHRASE MPQAFLFDVI YEAYQQCSDF DLEFGTECLQ LALKYCHRKA
260 270 280 290 300
KLVEGPPALW KVTYKQDLCA AEAMIKEKIS QEICVVMNTK DEESVGHLLE
310 320 330 340 350
EALRKELNCM KITSTVMDHI GGDIRNFIEQ CYSFICVNVV SPDSQETRKL
360 370 380 390 400
LRILEESSLP LLYPVVVVLV HCFDFTSVPL AQKMESLVWI RGLAKEVKER
410 420 430 440
NILLSGLLLN YSQDEQKLQE SLGQSAAIIA ALVKERNSAL VGQLLVA
Length:447
Mass (Da):49,136
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAD883B5816D222AB
GO
Isoform 2 (identifier: Q5RJG7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     309-324: CMKITSTVMDHIGGDI → VSIQRMTWIKCHTFLW
     325-447: Missing.

Show »
Length:324
Mass (Da):35,695
Checksum:i4085DE834F5F32C3
GO
Isoform 3 (identifier: Q5RJG7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     277-286: EKISQEICVV → GVFNLVTVSA
     287-447: Missing.

Show »
Length:286
Mass (Da):30,985
Checksum:iFE87DDD1D5CFE53B
GO
Isoform 4 (identifier: Q5RJG7-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-99: Missing.
     277-286: EKISQEICVV → GVFNLVTVSA
     287-447: Missing.

Show »
Length:187
Mass (Da):20,770
Checksum:iCEDC60A2D423E288
GO
Isoform 5 (identifier: Q5RJG7-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     414-419: DEQKLQ → NFYYGG
     420-447: Missing.

Show »
Length:419
Mass (Da):46,292
Checksum:iFF280F53E42D031F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1Y7VM96A0A1Y7VM96_MOUSE
D-ribitol-5-phosphate cytidylyltran...
Crppa Ispd
397Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1Y7VK76A0A1Y7VK76_MOUSE
D-ribitol-5-phosphate cytidylyltran...
Crppa Ispd
348Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC32538 differs from that shown. Reason: Frameshift at position 48.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti178A → E in BAC31463 (PubMed:16141072).Curated1
Sequence conflicti228S → N in AAI18039 (PubMed:15489334).Curated1
Sequence conflicti342P → L in AAH24061 (PubMed:15489334).Curated1
Sequence conflicti352R → H in AAH24061 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0346671 – 99Missing in isoform 4. 1 PublicationAdd BLAST99
Alternative sequenceiVSP_034668277 – 286EKISQEICVV → GVFNLVTVSA in isoform 3 and isoform 4. 2 Publications10
Alternative sequenceiVSP_034669287 – 447Missing in isoform 3 and isoform 4. 2 PublicationsAdd BLAST161
Alternative sequenceiVSP_034670309 – 324CMKIT…IGGDI → VSIQRMTWIKCHTFLW in isoform 2. 2 PublicationsAdd BLAST16
Alternative sequenceiVSP_034671325 – 447Missing in isoform 2. 2 PublicationsAdd BLAST123
Alternative sequenceiVSP_034672414 – 419DEQKLQ → NFYYGG in isoform 5. 1 Publication6
Alternative sequenceiVSP_034673420 – 447Missing in isoform 5. 1 PublicationAdd BLAST28

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK039004 mRNA Translation: BAC30199.1
AK043122 mRNA Translation: BAC31463.1
AK045940 mRNA Translation: BAC32538.1 Frameshift.
BC024061 mRNA Translation: AAH24061.1
BC086665 mRNA Translation: AAH86665.1
BC096030 mRNA Translation: AAH96030.1
BC118038 mRNA Translation: AAI18039.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS49051.1 [Q5RJG7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001276431.1, NM_001289502.1
NP_001276432.1, NM_001289503.1
NP_001276433.1, NM_001289504.1 [Q5RJG7-3]
NP_848744.2, NM_178629.6 [Q5RJG7-1]
XP_006515307.1, XM_006515244.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000062041; ENSMUSP00000061646; ENSMUSG00000043153 [Q5RJG7-1]
ENSMUST00000220519; ENSMUSP00000152423; ENSMUSG00000043153 [Q5RJG7-3]
ENSMUST00000221452; ENSMUSP00000152115; ENSMUSG00000043153 [Q5RJG7-5]
ENSMUST00000221895; ENSMUSP00000152392; ENSMUSG00000043153 [Q5RJG7-2]
ENSMUST00000223068; ENSMUSP00000152318; ENSMUSG00000043153 [Q5RJG7-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
75847

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:75847

UCSC genome browser

More...
UCSCi
uc007njy.3 mouse [Q5RJG7-3]
uc007njz.3 mouse [Q5RJG7-2]
uc007nkb.3 mouse [Q5RJG7-1]
uc007nkd.1 mouse [Q5RJG7-4]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK039004 mRNA Translation: BAC30199.1
AK043122 mRNA Translation: BAC31463.1
AK045940 mRNA Translation: BAC32538.1 Frameshift.
BC024061 mRNA Translation: AAH24061.1
BC086665 mRNA Translation: AAH86665.1
BC096030 mRNA Translation: AAH96030.1
BC118038 mRNA Translation: AAI18039.1
CCDSiCCDS49051.1 [Q5RJG7-1]
RefSeqiNP_001276431.1, NM_001289502.1
NP_001276432.1, NM_001289503.1
NP_001276433.1, NM_001289504.1 [Q5RJG7-3]
NP_848744.2, NM_178629.6 [Q5RJG7-1]
XP_006515307.1, XM_006515244.3

3D structure databases

SMRiQ5RJG7
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ5RJG7, 1 interactor
MINTiQ5RJG7
STRINGi10090.ENSMUSP00000061646

PTM databases

PhosphoSitePlusiQ5RJG7

Proteomic databases

PaxDbiQ5RJG7
PRIDEiQ5RJG7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000062041; ENSMUSP00000061646; ENSMUSG00000043153 [Q5RJG7-1]
ENSMUST00000220519; ENSMUSP00000152423; ENSMUSG00000043153 [Q5RJG7-3]
ENSMUST00000221452; ENSMUSP00000152115; ENSMUSG00000043153 [Q5RJG7-5]
ENSMUST00000221895; ENSMUSP00000152392; ENSMUSG00000043153 [Q5RJG7-2]
ENSMUST00000223068; ENSMUSP00000152318; ENSMUSG00000043153 [Q5RJG7-4]
GeneIDi75847
KEGGimmu:75847
UCSCiuc007njy.3 mouse [Q5RJG7-3]
uc007njz.3 mouse [Q5RJG7-2]
uc007nkb.3 mouse [Q5RJG7-1]
uc007nkd.1 mouse [Q5RJG7-4]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
729920
MGIiMGI:1923097 Crppa

Phylogenomic databases

eggNOGiENOG410IIH2 Eukaryota
COG1211 LUCA
GeneTreeiENSGT00390000006412
InParanoidiQ5RJG7
KOiK21031
OMAiERQHSVY
OrthoDBi1356473at2759
PhylomeDBiQ5RJG7
TreeFamiTF328415

Enzyme and pathway databases

UniPathwayiUPA00378

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q5RJG7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000043153 Expressed in 150 organ(s), highest expression level in lumbar subsegment of spinal cord
ExpressionAtlasiQ5RJG7 baseline and differential
GenevisibleiQ5RJG7 MM

Family and domain databases

CDDicd02516 CDP-ME_synthetase, 1 hit
Gene3Di3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR034683 IspD/TarI
IPR040635 ISPD_C
IPR018294 ISPD_synthase_CS
IPR029044 Nucleotide-diphossugar_trans
PfamiView protein in Pfam
PF01128 IspD, 1 hit
PF18706 ISPD_C, 1 hit
SUPFAMiSSF53448 SSF53448, 1 hit
PROSITEiView protein in PROSITE
PS01295 ISPD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiISPD_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5RJG7
Secondary accession number(s): Q148Q0
, Q501J8, Q8BR14, Q8C934, Q8CAE0, Q8CIF0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: December 21, 2004
Last modified: July 3, 2019
This is version 96 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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