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UniProtKB - Q5RHP9 (ERIC3_HUMAN)

Entry version 99 (18 Sep 2019)
Sequence version 1 (21 Dec 2004)
Previous versions | rss
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Protein

Glutamate-rich protein 3

Gene

ERICH3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Glutamate-rich protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ERICH3
Synonyms:C1orf173
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:25346 ERICH3

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5RHP9

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000178965

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142672422

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ERICH3

Domain mapping of disease mutations (DMDM)

More...DMDMi		74743374

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003049721 – 1530Glutamate-rich protein 3Add BLAST1530

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q5RHP9

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5RHP9

PeptideAtlas

More...PeptideAtlasi		Q5RHP9

PRoteomics IDEntifications database

More...PRIDEi		Q5RHP9

ProteomicsDB human proteome resource

More...ProteomicsDBi		63735 [Q5RHP9-1]
63736 [Q5RHP9-2]
63737 [Q5RHP9-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5RHP9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5RHP9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000178965 Expressed in 118 organ(s), highest expression level in bronchial epithelial cell

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q5RHP9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5RHP9 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA028655

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		126046, 3 interactors

Protein interaction database and analysis system

More...IntActi		Q5RHP9, 7 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000322609

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi254 – 259Poly-Arg6
Compositional biasi415 – 1489Glu-richAdd BLAST1075

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IE95 Eukaryota
ENOG410XT2H LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00530000064485

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000111262

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5RHP9

Identification of Orthologs from Complete Genome Data

More...OMAi		MVQGESE

Database of Orthologous Groups

More...OrthoDBi		213114at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5RHP9

TreeFam database of animal gene trees

More...TreeFami		TF331348

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR027962 DUF4590

The PANTHER Classification System

More...PANTHERi		PTHR23034 PTHR23034, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15257 DUF4590, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5RHP9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSHSHPAGLL AAYNSLMDKH LAGYFNNTRI RRHLLRSGLI TRSGRILSEK 
        60         70         80         90        100
EYKLNMMKRD HQKYIRECLA QAIFHKVLDM ERYHQLEIKK KLETLARKER 
       110        120        130        140        150
IQRFKGEHTR RSVENNMPIL SPHPPVGPKS NRGHSVLVDE GHSSPLALTA 
       160        170        180        190        200
PRPYTAPGNM QPPIRLQPLP SNPAVETVPK VTSRSRSKTS LLENEALFPI 
       210        220        230        240        250
GGKKAVMKFR NSIGNSQRMN SYQLPNINSY MMPIPPPLPP TGKITRENRS 
       260        270        280        290        300
ETWRRRRFRP TTAPNGLEPL LTKDSRRIHK TSLHSNAAIT MIYLGKNVHL 
       310        320        330        340        350
SSDNPDFRDE IKVYQQHCGG ENLCVYKGKL LEKETFQFIS KRHHGFPFSL 
       360        370        380        390        400
TFFLNGMQVN RLSSCCEYKH RKGSRLGGKR GYFGFVCVER SSPCYKCIIA 
       410        420        430        440        450
MGLDKKPSLP KSRKEKSTEK GEELKKAEGK VRKEREYVIP KRNEIKENKT 
       460        470        480        490        500
SVSAKFSAQE IKTGLKEVVT AVEEMTSKGK PGQEVLEDDQ ENTLKYEYEE 
       510        520        530        540        550
DFEVDEEKQG EKSNEEGQAD VQMNGIPQSP LDDKKDNLDP EKESETSSQK 
       560        570        580        590        600
APDARDNVKD ENDGCSESEL EEDKQDMKTA SSTSSRSHPY SSDSEDESAV 
       610        620        630        640        650
GDREAHTDSS TDESARRSSS QELSENDKPR KSHLPIEESL EIEIEDQEIT 
       660        670        680        690        700
KADVETKPMP IDESFENVLK EGTEKGTQEI AEGLSEKSGK HVSAEEKEKD 
       710        720        730        740        750
KSKLWEESTA QVKDKKAGLP GLEEGGKDSL PLAYVLALGA PTMNFMVDET 
       760        770        780        790        800
AAINSNKESQ QLVQKTYTLE KKEAMEEDEA PQHRDADIVQ GKGEAALWGE 
       810        820        830        840        850
AGAVHEAPLR AWKPTAEQPE LAEEFTEKRE IPPGIERGAE GAAEAEGVRR 
       860        870        880        890        900
LGEGGSDPIG QAAAKDAVGL SKDEAPEKQA LMLTVLETDK AASEGEQGLE 
       910        920        930        940        950
KAVLANEAAA LNLEHLHEVA ALREAATSEE GEAEGGVAVS DVGESEEEAS 
       960        970        980        990       1000
IDLEDTGPME DTASKREDGS EEAILGGEEP AKERKEVMRT ETRLSPFTGE 
      1010       1020       1030       1040       1050
AEASRMQVSE GSPEEGSLAK EAFLCKEDVE GEEMVTEAEA NREDDRKEIL 
      1060       1070       1080       1090       1100
PKELDLARER RKAERPKTSL RKTDSEREEV TRANALKDED AFKEEQKLKA 
      1110       1120       1130       1140       1150
EEGETETEVR AEEETKAPPN EMGSDAENEA PVEASELSDN PGLLGEDSLK 
      1160       1170       1180       1190       1200
ETVVPIFEAT PGFEKSLENI TALRKEGGGE RLSEARDTEH KDREELSSRE 
      1210       1220       1230       1240       1250
NRALKEGHRQ DGEGALAAPE AEPAGKVQAP EGLIPATGQA EELAAKDHDS 
      1260       1270       1280       1290       1300
CAGLEGRAEG QGGVDVVLRT QEAVAEEDPI MAEKFREEAV DEDPEEEEDK 
      1310       1320       1330       1340       1350
ECTLETEAMQ DRNSEGDGDM EGEGNTQKNE GMGGGRVVAV EVLHGGGETA 
      1360       1370       1380       1390       1400
ETAAEEREVL AGSETAEEKT IANKASSFSD VAEEETWHQQ DELVGKTAAA 
      1410       1420       1430       1440       1450
GKVVVEELAR SGEEVPAAEE MTVTYTTEAG VGTPGALERK TSGLGQEQEE 
      1460       1470       1480       1490       1500
GSEGQEAATG SGDGRQETGA AEKFRLGLSR EGERELSPES LQAMATLPVK 
      1510       1520       1530
PDFTETREKQ QHMVQGESET ADVSPNNVQV
Length:1,530
Mass (Da):168,466
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0FC967F01BB92585
GO
Isoform 2 (identifier: Q5RHP9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-742: Missing.

Note: No experimental confirmation available.
Show »
Length:788
Mass (Da):84,665
Checksum:iCF6C6183250D2D2B
GO
Isoform 3 (identifier: Q5RHP9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-197: Missing.
     198-201: FPIG → MLAK
     728-730: DSL → YGR
     731-1530: Missing.

Note: No experimental confirmation available.
Show »
Length:533
Mass (Da):60,256
Checksum:i31386B3A39444B50
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
R4GMY5R4GMY5_HUMAN
Glutamate-rich protein 3
ERICH3
110Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC86994 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1101E → G in BAC86994 (PubMed:14702039).Curated1
Sequence conflicti1177Missing in CAD39076 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_035131264P → A1 PublicationCorresponds to variant dbSNP:rs11210490Ensembl.1
Natural variantiVAR_035132555R → H. Corresponds to variant dbSNP:rs696698Ensembl.1
Natural variantiVAR_035133636I → V. Corresponds to variant dbSNP:rs17095653Ensembl.1
Natural variantiVAR_035134691H → R. Corresponds to variant dbSNP:rs2305549Ensembl.1
Natural variantiVAR_0351351056L → V. Corresponds to variant dbSNP:rs11580409Ensembl.1
Natural variantiVAR_0351361528V → M1 PublicationCorresponds to variant dbSNP:rs9326116Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0281591 – 742Missing in isoform 2. 1 PublicationAdd BLAST742
Alternative sequenceiVSP_0281601 – 197Missing in isoform 3. 1 PublicationAdd BLAST197
Alternative sequenceiVSP_028161198 – 201FPIG → MLAK in isoform 3. 1 Publication4
Alternative sequenceiVSP_028162728 – 730DSL → YGR in isoform 3. 1 Publication3
Alternative sequenceiVSP_028163731 – 1530Missing in isoform 3. 1 PublicationAdd BLAST800

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL834414 mRNA Translation: CAD39076.1
CR749349 mRNA Translation: CAH18202.1
AC096950 Genomic DNA No translation available.
BX470253 Genomic DNA No translation available.
BC073916 mRNA Translation: AAH73916.1
AK127470 mRNA Translation: BAC86994.1 Sequence problems.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS30755.1 [Q5RHP9-1]

NCBI Reference Sequences

More...RefSeqi		NP_001002912.4, NM_001002912.4 [Q5RHP9-1]
XP_016855763.1, XM_017000274.1 [Q5RHP9-1]
XP_016855767.1, XM_017000278.1 [Q5RHP9-2]
XP_016855768.1, XM_017000279.1 [Q5RHP9-2]
XP_016855769.1, XM_017000280.1 [Q5RHP9-2]
XP_016855770.1, XM_017000281.1 [Q5RHP9-2]
XP_016855771.1, XM_017000282.1 [Q5RHP9-2]
XP_016855772.1, XM_017000283.1 [Q5RHP9-2]
XP_016855773.1, XM_017000284.1 [Q5RHP9-2]
XP_016855774.1, XM_017000285.1 [Q5RHP9-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000326665; ENSP00000322609; ENSG00000178965 [Q5RHP9-1]
ENST00000420661; ENSP00000398581; ENSG00000178965 [Q5RHP9-3]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		127254

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:127254

UCSC genome browser

More...UCSCi		uc001dgg.3 human [Q5RHP9-1]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL834414 mRNA Translation: CAD39076.1
CR749349 mRNA Translation: CAH18202.1
AC096950 Genomic DNA No translation available.
BX470253 Genomic DNA No translation available.
BC073916 mRNA Translation: AAH73916.1
AK127470 mRNA Translation: BAC86994.1 Sequence problems.
CCDSiCCDS30755.1 [Q5RHP9-1]
RefSeqiNP_001002912.4, NM_001002912.4 [Q5RHP9-1]
XP_016855763.1, XM_017000274.1 [Q5RHP9-1]
XP_016855767.1, XM_017000278.1 [Q5RHP9-2]
XP_016855768.1, XM_017000279.1 [Q5RHP9-2]
XP_016855769.1, XM_017000280.1 [Q5RHP9-2]
XP_016855770.1, XM_017000281.1 [Q5RHP9-2]
XP_016855771.1, XM_017000282.1 [Q5RHP9-2]
XP_016855772.1, XM_017000283.1 [Q5RHP9-2]
XP_016855773.1, XM_017000284.1 [Q5RHP9-2]
XP_016855774.1, XM_017000285.1 [Q5RHP9-2]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGridi126046, 3 interactors
IntActiQ5RHP9, 7 interactors
STRINGi9606.ENSP00000322609

PTM databases

iPTMnetiQ5RHP9
PhosphoSitePlusiQ5RHP9

Polymorphism and mutation databases

BioMutaiERICH3
DMDMi74743374

Proteomic databases

MassIVEiQ5RHP9
PaxDbiQ5RHP9
PeptideAtlasiQ5RHP9
PRIDEiQ5RHP9
ProteomicsDBi63735 [Q5RHP9-1]
63736 [Q5RHP9-2]
63737 [Q5RHP9-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000326665; ENSP00000322609; ENSG00000178965 [Q5RHP9-1]
ENST00000420661; ENSP00000398581; ENSG00000178965 [Q5RHP9-3]
GeneIDi127254
KEGGihsa:127254
UCSCiuc001dgg.3 human [Q5RHP9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		127254

GeneCards: human genes, protein and diseases

More...GeneCardsi		ERICH3
HGNCiHGNC:25346 ERICH3
HPAiHPA028655
neXtProtiNX_Q5RHP9
OpenTargetsiENSG00000178965
PharmGKBiPA142672422

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410IE95 Eukaryota
ENOG410XT2H LUCA
GeneTreeiENSGT00530000064485
HOGENOMiHOG000111262
InParanoidiQ5RHP9
OMAiMVQGESE
OrthoDBi213114at2759
PhylomeDBiQ5RHP9
TreeFamiTF331348

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ERICH3 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		127254

Pharos

More...Pharosi		Q5RHP9

Protein Ontology

More...PROi		PR:Q5RHP9

Gene expression databases

BgeeiENSG00000178965 Expressed in 118 organ(s), highest expression level in bronchial epithelial cell
ExpressionAtlasiQ5RHP9 baseline and differential
GenevisibleiQ5RHP9 HS

Family and domain databases

InterProiView protein in InterPro
IPR027962 DUF4590
PANTHERiPTHR23034 PTHR23034, 1 hit
PfamiView protein in Pfam
PF15257 DUF4590, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiERIC3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5RHP9
Secondary accession number(s): Q68DL8
, Q6GMR8, Q6ZSF9, Q8ND41
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: December 21, 2004
Last modified: September 18, 2019
This is version 99 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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