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Entry version 100 (13 Feb 2019)
Sequence version 1 (21 Dec 2004)
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Protein

Intraflagellar transport protein 172 homolog

Gene

ift172

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for the maintenance and formation of cilia.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • cilium assembly Source: ZFIN
  • photoreceptor cell maintenance Source: ZFIN
  • pronephros development Source: ZFIN
  • regulation of TOR signaling Source: ZFIN
  • retina development in camera-type eye Source: ZFIN

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DRE-5610787 Hedgehog 'off' state
R-DRE-5620924 Intraflagellar transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Intraflagellar transport protein 172 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ift172
ORF Names:si:dkey-221h15.5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-040827-1 ift172

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Fishes display cysts in the glomerular-tubular region of the kidney similar to cystic kidney disease. Knockdown of the gene with 2 morpholino oligonucleotides leads to ventral body-axis curvature, formation of kidney cysts, otolith defects, and hydrocephalus, as well as cartilage defects of the craniofacial skeleton. Knockdown of the gene in a rhodopsin-GFP transgenic line demonstrates that the level of rhodopsin-GFP is lower in ift172 morphants than controls, suggesting retinal degeneration. Scanning electron microscopy of the olfactory placode reveales ciliogenesis defects in morphants, including shortened and truncated cilia.2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003289441 – 1745Intraflagellar transport protein 172 homologAdd BLAST1745

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5RHH4

PRoteomics IDEntifications database

More...
PRIDEi
Q5RHH4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000041870 Expressed in 28 organ(s), highest expression level in testis

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000061333

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q5RHH4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati14 – 53WD 1Add BLAST40
Repeati64 – 103WD 2Add BLAST40
Repeati110 – 148WD 3Add BLAST39
Repeati150 – 190WD 4Add BLAST41
Repeati195 – 233WD 5Add BLAST39
Repeati238 – 278WD 6Add BLAST41
Repeati284 – 323WD 7Add BLAST40
Repeati483 – 521WD 8Add BLAST39
Repeati522 – 559WD 9Add BLAST38
Repeati680 – 725WD 10Add BLAST46
Repeati691 – 725TPR 1Add BLAST35
Repeati750 – 784TPR 2Add BLAST35
Repeati809 – 842TPR 3Add BLAST34
Repeati854 – 887TPR 4Add BLAST34
Repeati912 – 945TPR 5Add BLAST34
Repeati947 – 971TPR 6Add BLAST25
Repeati972 – 1004TPR 7Add BLAST33
Repeati1042 – 1075TPR 8Add BLAST34
Repeati1272 – 1305TPR 9Add BLAST34
Repeati1328 – 1361TPR 10Add BLAST34
Repeati1407 – 1441TPR 11Add BLAST35

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the IFT172 family.Curated

Keywords - Domaini

Repeat, TPR repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3616 Eukaryota
ENOG410XR2C LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153417

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000259226

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG098449

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5RHH4

KEGG Orthology (KO)

More...
KOi
K19676

Identification of Orthologs from Complete Genome Data

More...
OMAi
RLSEVAW

Database of Orthologous Groups

More...
OrthoDBi
30851at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5RHH4

TreeFam database of animal gene trees

More...
TreeFami
TF312901

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 1 hit
2.130.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011990 TPR-like_helical_dom_sf
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR036322 WD40_repeat_dom_sf

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320 WD40, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978 SSF50978, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5RHH4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQLKYMKTLL TPQDGAAKVT CMAWAPNNAK FAVCTIDRVV ILYDEQGEKR
60 70 80 90 100
DRFTTKPADP KYGKKTYVVK SMAFSPDSTK IAVAQTDNII FVYKIGEEWG
110 120 130 140 150
DKKVICNKFI QTSAVTSLVW PSEHAIIFGL AEGKVRQANT KTSKSSTIYG
160 170 180 190 200
TDSYVVSLTS NVSGKGILSG HADGTVVRYF IDDEGSGESQ GKLLTHACPP
210 220 230 240 250
YALAWGTNSI IVAGCDKKIV AYGKEGNVIQ TFDYSRDRAE KEFTVAASSP
260 270 280 290 300
SGQSIVVGSF DRLRVFNWSP RKGTWDESSP KEIPNLYTIT ALSWKKDGSR
310 320 330 340 350
LSVGTLCGGV EMFDCCLRRS IYKNKFEMTY VGLSQVIVRN LSTGTRVVLK
360 370 380 390 400
SQYGYEIDEV KVMGKDQYLV AHTSDTLLLG DLVSNKLSEV AWQGSGGNEK
410 420 430 440 450
FFFENETVCM IFNAGELALV EYGSNDILGS VRTEFMNPHL ISVRLNERRQ
460 470 480 490 500
RGVEDNKKLA YLIDIKTIAI VDLVGGYNLG TISHDSKIDW LELNETGRKL
510 520 530 540 550
LFRDKKLRLH LYDIESSVKS TMLSFCPYVQ WVPGSDVVVA QNRGNLCVWY
560 570 580 590 600
TIDSPERVTM FPLKGDIVDL ERSNGKTEVI VNEGVNSISY TLDEGLIEFG
610 620 630 640 650
TAIDDGDYYR ATAFLETLEM SAETEAMWKT LSKLSLEAQQ LHIAERCFAA
660 670 680 690 700
LGDVSKARFL NETNKIADAV AKEYDGDGTD HYQVKARLAM LDKNFKLAEM
710 720 730 740 750
YYMEQNAVDE VMEMYQELHM WDECIAVAEG KGHPELDNLR RSYYSYLMET
760 770 780 790 800
NQNEKAAEVK ENEGDFTGAV NLYLKAGLPA KAAWLAMSKD ELLSSQDIVS
810 820 830 840 850
RITAALIKGE FYERAGDLFE RTRNNQRALE CYRKGNAFKK AVDLARVAFP
860 870 880 890 900
AEVVKLEEVW GDYLVQQKQM DAAINHYIEA GRSIKAIEAA IAARQWKKAL
910 920 930 940 950
HILELQEDRT AAKYYLKIAQ YYASVQEFEV AERLFVKGDH IKDAIDMYTQ
960 970 980 990 1000
AGRWEQAHKL AVKCMTQEDV SVLYVSRAQE LEKEGKYKEA ERLFTTVDEP
1010 1020 1030 1040 1050
DLAITMYKKN KMYDDMIRLV AVHHKDLLQE THIHLAKELE AESRFQEAEY
1060 1070 1080 1090 1100
HYLEGQDWKA AVNMYRVNDM WEEAYRIAKT HGGANAHKQV AYLWAKSLGG
1110 1120 1130 1140 1150
EAAVKLLNKF GLLETAIDFA ADNYTFDFAF ELARLSMKQK IPDIHLKNAM
1160 1170 1180 1190 1200
FLEDQGKFNE AEIEFIKAGK PKEAVLMHVH NKDWSNAQRV AEAHDPESVA
1210 1220 1230 1240 1250
DILVSQAKFC FDQKEFQKAE AFLLRAQRPE LAIKYYKDAG MWTDAMRICK
1260 1270 1280 1290 1300
DYLPSKLSVL QKEYESEGNW GVEGMIEQAQ EWEQTGEYSR AVDCYLKVKD
1310 1320 1330 1340 1350
SSNLDLLLKC WMKAAELAIK FLSHDKAVDV SQIVGPRLIQ LRKYNEAAEL
1360 1370 1380 1390 1400
YLNLDLIKNA IDAFIEGEEW NKAKRVAKEL DPRLEEYVDK RYKEHLKNQG
1410 1420 1430 1440 1450
KVDSLVGVDV VAALDMYAER GQWEKCIDTA SKQNFKVLHK YIALYATHLI
1460 1470 1480 1490 1500
KEGEVEKVLS LYIQHGVPAY SQNFNIYKRM FQELVNLRDR DCAEAFRMWS
1510 1520 1530 1540 1550
DLRDVLLLLC ENLTKSSEAN SPAHEEFEQM LLVAHYYATR SAAKGIDQLS
1560 1570 1580 1590 1600
SVAAKLSISL LRHTELIPAD KAFYEAGLAA KAVGWENMAF IFLNRFLDLA
1610 1620 1630 1640 1650
DGIDEGTLDA LDHTDFQDTD IPFEVPVPSR LHVTVEKREE IREWVLTVSM
1660 1670 1680 1690 1700
DQRVEQVLPK DERGTYEASL VAASTGIRSL PCVITGYPVL RNKIEFKRPG
1710 1720 1730 1740
MAANKDDWNK FLMATKTTHS PECQDVLKFI TQWCGGLPSA GYSFH
Length:1,745
Mass (Da):197,780
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC4C875DFA684497C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti436M → I in AAT39119 (PubMed:15269167).Curated1
Sequence conflicti799V → I in AAT39119 (PubMed:15269167).Curated1
Sequence conflicti884I → T in AAT39119 (PubMed:15269167).Curated1
Sequence conflicti921Y → H in AAT39119 (PubMed:15269167).Curated1
Sequence conflicti925V → L in AAT39119 (PubMed:15269167).Curated1
Sequence conflicti1157K → N in AAT39119 (PubMed:15269167).Curated1
Sequence conflicti1287E → D in AAT39119 (PubMed:15269167).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY618923 mRNA Translation: AAT39119.1
BX511178 Genomic DNA Translation: CAI20958.1

NCBI Reference Sequences

More...
RefSeqi
NP_001002312.1, NM_001002312.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Dr.19771

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000061334; ENSDARP00000061333; ENSDARG00000041870

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
432389

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:432389

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY618923 mRNA Translation: AAT39119.1
BX511178 Genomic DNA Translation: CAI20958.1
RefSeqiNP_001002312.1, NM_001002312.1
UniGeneiDr.19771

3D structure databases

ProteinModelPortaliQ5RHH4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000061333

Proteomic databases

PaxDbiQ5RHH4
PRIDEiQ5RHH4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000061334; ENSDARP00000061333; ENSDARG00000041870
GeneIDi432389
KEGGidre:432389

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
26160
ZFINiZDB-GENE-040827-1 ift172

Phylogenomic databases

eggNOGiKOG3616 Eukaryota
ENOG410XR2C LUCA
GeneTreeiENSGT00940000153417
HOGENOMiHOG000259226
HOVERGENiHBG098449
InParanoidiQ5RHH4
KOiK19676
OMAiRLSEVAW
OrthoDBi30851at2759
PhylomeDBiQ5RHH4
TreeFamiTF312901

Enzyme and pathway databases

ReactomeiR-DRE-5610787 Hedgehog 'off' state
R-DRE-5620924 Intraflagellar transport

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q5RHH4

Gene expression databases

BgeeiENSDARG00000041870 Expressed in 28 organ(s), highest expression level in testis

Family and domain databases

Gene3Di1.25.40.10, 1 hit
2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR011990 TPR-like_helical_dom_sf
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR036322 WD40_repeat_dom_sf
SMARTiView protein in SMART
SM00320 WD40, 6 hits
SUPFAMiSSF50978 SSF50978, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIF172_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5RHH4
Secondary accession number(s): Q6IVW1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: December 21, 2004
Last modified: February 13, 2019
This is version 100 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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