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Entry version 93 (07 Oct 2020)
Sequence version 2 (10 Jul 2007)
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Protein
Submitted name:

UHRF1-binding protein 1-like

Gene

uhrf1bp1l

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
UHRF1-binding protein 1-likeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:uhrf1bp1lImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-041210-177, uhrf1bp1l

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5RGW0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000004055, Expressed in liver and 25 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5RGW0, baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000122870

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 94Chorein_NInterPro annotationAdd BLAST92

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni265 – 286DisorderedSequence analysisAdd BLAST22
Regioni407 – 436DisorderedSequence analysisAdd BLAST30
Regioni871 – 914DisorderedSequence analysisAdd BLAST44
Regioni926 – 1011DisorderedSequence analysisAdd BLAST86
Regioni1397 – 1416DisorderedSequence analysisAdd BLAST20

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi874 – 894PolarSequence analysisAdd BLAST21
Compositional biasi926 – 950PolarSequence analysisAdd BLAST25
Compositional biasi957 – 974PolyampholyteSequence analysisAdd BLAST18
Compositional biasi975 – 1011PolarSequence analysisAdd BLAST37

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2955, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00600000084428

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5RGW0

Database of Orthologous Groups

More...
OrthoDBi
64302at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5RGW0

TreeFam database of animal gene trees

More...
TreeFami
TF314874

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026728, UHRF1BP1-like
IPR026854, VPS13-like_N

The PANTHER Classification System

More...
PANTHERi
PTHR22774, PTHR22774, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12624, Chorein_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q5RGW0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGLIKKQIL KHLSRFAKNL SPDKINLSTL KGEGQLTNLE LDEEVLQNML
60 70 80 90 100
DLPTWLAINK VFCNKAAIRI PWTKLKTHPI SLSLDKVVME MSTCDEPRPP
110 120 130 140 150
NGPSPIATAS GQSEYGFAEK VVEGISLSVN SIVIRISAKA FNASFELSQL
160 170 180 190 200
QVYSVNTSWT TGDLRYTRIL DPTRGELLTF KEVSWQMIRI EADAIQNTEH
210 220 230 240 250
EVVSAPIRLI TNQSKIRVTL KRRMKDCNVI ASKLTLILDD LLWVLTDSQL
260 270 280 290 300
KAMVQYAKSL SESMEKSASQ RKSMAPDTTQ VTPAPPTAQQ MRTQQASAAA
310 320 330 340 350
DQTASMARLF TAYDVRETSH HLQITHLDLH ICDDTNAKDR GINKRLDGGA
360 370 380 390 400
MQLSFSSISV DYYPFHKAGE GCLHWMHYGE ATKSRETWAR SLLDEFKSNV
410 420 430 440 450
DMLKNAVSGQ SQGSPQHGKI STSSSTSFSP PTPPRTQLMS SSIVLRMADF
460 470 480 490 500
SIYQVSSADQ PRSSPQTMIS CNKKSLYLPQ EMPAIHAEFT EYYFPDGKDY
510 520 530 540 550
PVPCPNLYVQ LNALQLVLDS RSLVWLNLFA LDLRQSLEQF MDLYKLNDSQ
560 570 580 590 600
KPEEHVDIKV DGLMLKLVIP ADHEKTQPDQ PRSVSVQTSE MVATNTRHSS
610 620 630 640 650
ACSRSSLEAL LQAFQEQPFF TSLSSTFPRA PSSFSVLHSV FQRHAHEQDT
660 670 680 690 700
RVHDVYRGLA PPSLSTNALK TPAATDLWAM HFSQFWVDYE GSRSGRGRPT
710 720 730 740 750
PCVDSFPLTL WVCHPARYTQ HLERLRVGSG LLPRSESAEM ANRLQRKKLL
760 770 780 790 800
KEYYSTNASP SDTPSNGLHK PQSLDGLFSD SSSSLPLACS ANEVDVQVLV
810 820 830 840 850
HVQKHLSAQV SHGQYVFLLR LQHAVKTLQR TIQQDLEQYG SKRLGPTQPF
860 870 880 890 900
SACVGVLMKS AEVALLLKPI PQPDLSTSPL NSDVSPSESR ATLEAGSEVS
910 920 930 940 950
EGHERPSAAG EGTRNVDQLL CADRNSIDTS PLLPSSSSAL RKTSMDERSS
960 970 980 990 1000
VASGGRVPSE EKKDLREGSP DGDTSRSEAK GQQNETSQSG MAVVDPISDT
1010 1020 1030 1040 1050
SSREWNDKSQ GARLPQSMSR YCVVCAYRTQ LPIPSSWFLF YLFTNLHGRL
1060 1070 1080 1090 1100
MQGKSQSSFS VSYKNMKKSP SLQSLDDLSM DSYLLEDCDS YSLLDRDDVS
1110 1120 1130 1140 1150
ISGFKEALNE RISTDGSVTL AQEADEAQSP DAISAASQSI DEPMKDLVSV
1160 1170 1180 1190 1200
LVMKVYSVCC SLDLKGDDTA VALEVGRVQP NQLGNVSLRQ YLSNRSLGSG
1210 1220 1230 1240 1250
SGSDPSAVLL NPEVQVRLES GPSAAVHSPL AEQNGFLQCR LQAFNTDFLI
1260 1270 1280 1290 1300
TSLRNLALFL EDDSASQVLP MEITIKDTHV NLKDDGPRDN ISEPEPSPIS
1310 1320 1330 1340 1350
VHIHNLLIHR QDDGSFSIGG AERAVDSQLQ TAGPVNDSRL SSVPEVPVGV
1360 1370 1380 1390 1400
KATQTAPLSP TSPGPSSREQ LLVEENECLK LELSKAKMAL AEAQMEKDSL
1410
QHQMKTLKLT SGGSNS
Length:1,416
Mass (Da):155,917
Last modified:July 10, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAF65E72F439ACD14
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F1R2T5F1R2T5_DANRE
UHRF1-binding protein 1-like
uhrf1bp1l
1,417Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A286YAW0A0A286YAW0_DANRE
UHRF1-binding protein 1-like
uhrf1bp1l
1,402Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX649503 Genomic DNA No translation available.
BX901882 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001093475.1, NM_001100005.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000135330; ENSDARP00000122870; ENSDARG00000004055

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
562208

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:562208

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX649503 Genomic DNA No translation available.
BX901882 Genomic DNA No translation available.
RefSeqiNP_001093475.1, NM_001100005.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000122870

Proteomic databases

PaxDbiQ5RGW0

Genome annotation databases

EnsembliENSDART00000135330; ENSDARP00000122870; ENSDARG00000004055
GeneIDi562208
KEGGidre:562208

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23074
ZFINiZDB-GENE-041210-177, uhrf1bp1l

Phylogenomic databases

eggNOGiKOG2955, Eukaryota
GeneTreeiENSGT00600000084428
InParanoidiQ5RGW0
OrthoDBi64302at2759
PhylomeDBiQ5RGW0
TreeFamiTF314874

Gene expression databases

BgeeiENSDARG00000004055, Expressed in liver and 25 other tissues
ExpressionAtlasiQ5RGW0, baseline

Family and domain databases

InterProiView protein in InterPro
IPR026728, UHRF1BP1-like
IPR026854, VPS13-like_N
PANTHERiPTHR22774, PTHR22774, 1 hit
PfamiView protein in Pfam
PF12624, Chorein_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5RGW0_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5RGW0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: July 10, 2007
Last modified: October 7, 2020
This is version 93 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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