Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Centrosomal protein of 76 kDa

Gene

CEP76

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication (By similarity).By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Centrosomal protein of 76 kDa
Short name:
Cep76
Gene namesi
Name:CEP76
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000895021 – 658Centrosomal protein of 76 kDaAdd BLAST658

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei74PhosphoserineBy similarity1
Modified residuei82PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Interactioni

Subunit structurei

Interacts with CCP110 and CEP97.By similarity

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000010081

Structurei

3D structure databases

SMRiQ5RCP7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CEP76 family.Curated

Phylogenomic databases

eggNOGiENOG410IFDB Eukaryota
ENOG410XWNZ LUCA
HOVERGENiHBG050901
InParanoidiQ5RCP7
KOiK16457

Family and domain databases

InterProiView protein in InterPro
IPR028926 CEP76-C2
IPR038765 Papain_like_cys_pep_sf
PfamiView protein in Pfam
PF15627 CEP76-C2, 1 hit
SUPFAMiSSF54001 SSF54001, 1 hit

Sequencei

Sequence statusi: Complete.

Q5RCP7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLPPEKASE LKQLIHQQLS KMDVHGRIRE ILAETIREEL APDQHLSTED
60 70 80 90 100
LIKALRRRGI IDDVMKELNF VTDSVERELP SSPKQPICFD RQSTLKKTNI
110 120 130 140 150
DPTRRYLYLQ VLGGKAFLEH LQEPEPLPGQ VCSTFTLCLH YRNQRFRSKP
160 170 180 190 200
VPCACEPDFH DGFLLEVHRE SLGDGTRMAD STTMLSISDP IHMVLIKTDI
210 220 230 240 250
FGETTLVASY FLEWRSVLGS ENGVTSLTVE LMGVGTESKV SVGILNIKLE
260 270 280 290 300
MYPPLNQTLS QEVVNTQLAL ERQKTAEKER LFLVYAKQWW REYLQIRPSH
310 320 330 340 350
NSRLVKIFAQ DENGVNRPVC SYVKPLRAGR LLDTPRQAAR FVNVLGYERA
360 370 380 390 400
PVIGGGGKQE QWCTLLAFLC RNKGDCEDHA NLLCSLLLGY GLEAFVCVGT
410 420 430 440 450
KAKGVPHAWV MTCGTDGTTT FWESLTGHRY IHKPTNPDEP PVAEQPKPLY
460 470 480 490 500
PYRTIGCVFN HQMFLGNCQP SDAVETCVFD LNDESKWKPM SEEAIKSVCA
510 520 530 540 550
PGATTSLPPF PPLCASTIDA SVTSNEIEMQ LRLLVSEHRK DLGLTTVWED
560 570 580 590 600
QLSYLLSPAL ASYEFERTTS ISAGNEEFQD AIRRAVPDGH TFKGFPIHFV
610 620 630 640 650
YRNARRAFAT CLRSPFCEEI ICCRGDQVRL AVRVRVFTYP ESACAVWIMF

ACKYRSVL
Length:658
Mass (Da):74,317
Last modified:December 21, 2004 - v1
Checksum:iD746E197B346B95F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR858222 mRNA Translation: CAH90460.1
RefSeqiNP_001125237.1, NM_001131765.1
UniGeneiPab.14010

Genome annotation databases

GeneIDi100172131
KEGGipon:100172131

Similar proteinsi

Entry informationi

Entry nameiCEP76_PONAB
AccessioniPrimary (citable) accession number: Q5RCP7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: December 21, 2004
Last modified: June 20, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health