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Protein

Ribonuclease P protein subunit p14

Gene

RPP14

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit p14 (EC:3.1.26.5)
Gene namesi
Name:RPP14
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001400121 – 124Ribonuclease P protein subunit p14Add BLAST124

Interactioni

Subunit structurei

RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40.By similarity

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000015396

Structurei

3D structure databases

ProteinModelPortaliQ5RB79
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG410IXUB Eukaryota
ENOG4112ADM LUCA
GeneTreeiENSGT00510000048121
HOVERGENiHBG079505
InParanoidiQ5RB79
KOiK14529
OMAiRNPSEHH
OrthoDBiEOG091G10J1
TreeFamiTF324711

Family and domain databases

Gene3Di3.30.70.3250, 1 hit
InterProiView protein in InterPro
IPR002759 RNase_P/MRP_subunit
IPR038085 Rnp2-like_sf
PfamiView protein in Pfam
PF01900 RNase_P_Rpp14, 1 hit
SUPFAMiSSF160350 SSF160350, 1 hit

Sequencei

Sequence statusi: Complete.

Q5RB79-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPAPAATYER VVYKNPSEYH YMKVCLEFQD CGVGLNAAQF KQLLISAVKD
60 70 80 90 100
LFGEVDAALP LDILTYEEKT LSAILRICSS GLVKLWSSLT LLGSYKGKKC
110 120
AFRVIQVSPF LLALSGNSRE LVLD
Length:124
Mass (Da):13,693
Last modified:January 23, 2007 - v3
Checksum:i10AF6C947785DD90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR858774 mRNA Translation: CAH90981.1
RefSeqiNP_001127358.1, NM_001133886.1
XP_009237129.1, XM_009238854.1

Genome annotation databases

EnsembliENSPPYT00000016009; ENSPPYP00000015396; ENSPPYG00000013762
GeneIDi100174423
KEGGipon:100174423

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR858774 mRNA Translation: CAH90981.1
RefSeqiNP_001127358.1, NM_001133886.1
XP_009237129.1, XM_009238854.1

3D structure databases

ProteinModelPortaliQ5RB79
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000015396

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPPYT00000016009; ENSPPYP00000015396; ENSPPYG00000013762
GeneIDi100174423
KEGGipon:100174423

Organism-specific databases

CTDi11102

Phylogenomic databases

eggNOGiENOG410IXUB Eukaryota
ENOG4112ADM LUCA
GeneTreeiENSGT00510000048121
HOVERGENiHBG079505
InParanoidiQ5RB79
KOiK14529
OMAiRNPSEHH
OrthoDBiEOG091G10J1
TreeFamiTF324711

Family and domain databases

Gene3Di3.30.70.3250, 1 hit
InterProiView protein in InterPro
IPR002759 RNase_P/MRP_subunit
IPR038085 Rnp2-like_sf
PfamiView protein in Pfam
PF01900 RNase_P_Rpp14, 1 hit
SUPFAMiSSF160350 SSF160350, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRPP14_PONAB
AccessioniPrimary (citable) accession number: Q5RB79
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 64 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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