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UniProtKB - Q5RB09 (GTR9_PONAB)
Protein
Solute carrier family 2, facilitated glucose transporter member 9
Gene
SLC2A9
Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Functioni
Urate transporter, which may play a role in the urate reabsorption by proximal tubules (By similarity).
Does not transport glucose, fructose or galactose (By similarity).
By similarityCatalytic activityi
GO - Molecular functioni
- urate transmembrane transporter activity Source: UniProtKB
GO - Biological processi
- urate transport Source: UniProtKB
Names & Taxonomyi
Protein namesi | Recommended name: Solute carrier family 2, facilitated glucose transporter member 9CuratedAlternative name(s): Glucose transporter type 9By similarity Short name: GLUT-9By similarity Urate transporterCurated |
Gene namesi | Name:SLC2A9By similarity Synonyms:GLUT9By similarity |
Organismi | Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
Taxonomic identifieri | 9601 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Pongo |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Basolateral cell membrane By similarity; Multi-pass membrane protein Sequence analysis
- Apical cell membrane By similarity; Multi-pass membrane protein Sequence analysis
Plasma Membrane
- apical plasma membrane Source: UniProtKB
- basolateral plasma membrane Source: UniProtKB
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 51 | CytoplasmicSequence analysisAdd BLAST | 51 | |
Transmembranei | 52 – 72 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 73 – 107 | ExtracellularSequence analysisAdd BLAST | 35 | |
Transmembranei | 108 – 128 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 129 – 140 | CytoplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 141 – 161 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 162 – 171 | ExtracellularSequence analysis | 10 | |
Transmembranei | 172 – 192 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 193 – 200 | CytoplasmicSequence analysis | 8 | |
Transmembranei | 201 – 221 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 222 – 231 | ExtracellularSequence analysis | 10 | |
Transmembranei | 232 – 252 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 253 – 316 | CytoplasmicSequence analysisAdd BLAST | 64 | |
Transmembranei | 317 – 337 | Helical; Name=7Sequence analysisAdd BLAST | 21 | |
Topological domaini | 338 – 354 | ExtracellularSequence analysisAdd BLAST | 17 | |
Transmembranei | 355 – 375 | Helical; Name=8Sequence analysisAdd BLAST | 21 | |
Topological domaini | 376 – 381 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 382 – 402 | Helical; Name=9Sequence analysisAdd BLAST | 21 | |
Topological domaini | 403 – 415 | ExtracellularSequence analysisAdd BLAST | 13 | |
Transmembranei | 416 – 436 | Helical; Name=10Sequence analysisAdd BLAST | 21 | |
Topological domaini | 437 – 451 | CytoplasmicSequence analysisAdd BLAST | 15 | |
Transmembranei | 452 – 472 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Topological domaini | 473 – 478 | ExtracellularSequence analysis | 6 | |
Transmembranei | 479 – 499 | Helical; Name=12Sequence analysisAdd BLAST | 21 | |
Topological domaini | 500 – 566 | CytoplasmicSequence analysisAdd BLAST | 67 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000292552 | 1 – 566 | Solute carrier family 2, facilitated glucose transporter member 9Add BLAST | 566 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 9 | PhosphoserineBy similarity | 1 | |
Glycosylationi | 74 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 90 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Modified residuei | 514 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
Glycoprotein, PhosphoproteinFamily & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 31 | DisorderedSequence analysisAdd BLAST | 31 | |
Regioni | 524 – 543 | DisorderedSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0569, Eukaryota |
InParanoidi | Q5RB09 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR045263, GLUT IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
PANTHERi | PTHR23503, PTHR23503, 1 hit |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5RB09-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MARKQNRNSK ELGLAPLADD TSHAGPPGPG RALLECDHLR SGLPDGRRRK
60 70 80 90 100
DWSCSLLVAS LAGAFGSSFL YGYNLSVVNA PTPYIKAFYN ESWERRHGRP
110 120 130 140 150
IDPDTLTLLW SVTVSIFAIG GLVGTLMVKM IGKVLGRKHT LLANNGFAIS
160 170 180 190 200
AALLMACSLQ AGAFEMLIVG RFIMGIDGGI ALSVLPMYLS EISPKEIRGS
210 220 230 240 250
LGQVTAIFIC IGVFTGQLLG LPELLGKEST WPYLFGVIVV PAVVQLLSLP
260 270 280 290 300
FLPDSPRYLL LEKRNEARAV KAFQTFLGKA DVSREVEEVA ESRVQRSIRL
310 320 330 340 350
VSVLELLRAP YVRWQVVTVI VTMACYQLCG LNAIWFYTNS IFGKAGIPPA
360 370 380 390 400
KIPYVTLSTG GIETLAAIFS GLVIEHLGRR PLLIGGFGLM ALFFGTLTVT
410 420 430 440 450
LTLQDRAPWV PYLSIVGILA IIASFCSGPG GIPFILTGEF FQQSQRPAAF
460 470 480 490 500
IIAGTVNWLS NFAVGLLFPF IQKSLDTYCF LVFATICMTG AIYLYFVLPE
510 520 530 540 550
TKNRTYAEIS QAFSKRNKAY PPEEKIDSAV TDGKTKGRPE QVSSSTLDNY
560
VKNRIVYMDD LTFQET
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR858850 mRNA Translation: CAH91051.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR858850 mRNA Translation: CAH91051.1 |
3D structure databases
SMRi | Q5RB09 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 9601.ENSPPYP00000016315 |
Phylogenomic databases
eggNOGi | KOG0569, Eukaryota |
InParanoidi | Q5RB09 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR045263, GLUT IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
PANTHERi | PTHR23503, PTHR23503, 1 hit |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GTR9_PONAB | |
Accessioni | Q5RB09Primary (citable) accession number: Q5RB09 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 26, 2007 |
Last sequence update: | December 21, 2004 | |
Last modified: | February 23, 2022 | |
This is version 69 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families