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Protein

Protein kish-A

Gene

TMEM167A

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the early part of the secretory pathway.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Protein kish-A
Alternative name(s):
Transmembrane protein 167
Transmembrane protein 167A
Gene namesi
Name:TMEM167A
Synonyms:TMEM167
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini27 – 53ExtracellularSequence analysisAdd BLAST27
Transmembranei54 – 71HelicalSequence analysisAdd BLAST18
Topological domaini72CytoplasmicSequence analysis1

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_000024777027 – 72Protein kish-AAdd BLAST46

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi35N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ5RAL1
SMRiQ5RAL1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the KISH family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3808 Eukaryota
ENOG4112243 LUCA
GeneTreeiENSGT00860000133824
HOVERGENiHBG080265
InParanoidiQ5RAL1
OMAiFSILFMQ
OrthoDBiEOG091G15C1
TreeFamiTF300138

Family and domain databases

InterProiView protein in InterPro
IPR009653 Ksh1
PANTHERiPTHR13229 PTHR13229, 1 hit
PfamiView protein in Pfam
PF06842 DUF1242, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5RAL1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAIFNFQSL LTVILLLICT CAYIRSLAPS LLDRNKTGLL GIFWKCARIG
60 70
ERKSPYVAVC CIVMAFSILF IQ
Length:72
Mass (Da):8,060
Last modified:December 21, 2004 - v1
Checksum:i1A346F4BE4FD8C19
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR859004 mRNA Translation: CAH91199.1
CR859096 mRNA Translation: CAH91288.1
RefSeqiNP_001128803.1, NM_001135331.1
UniGeneiPab.19597

Genome annotation databases

EnsembliENSPPYT00000018158; ENSPPYP00000017451; ENSPPYG00000015611
GeneIDi100189710
KEGGipon:100189710

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR859004 mRNA Translation: CAH91199.1
CR859096 mRNA Translation: CAH91288.1
RefSeqiNP_001128803.1, NM_001135331.1
UniGeneiPab.19597

3D structure databases

ProteinModelPortaliQ5RAL1
SMRiQ5RAL1
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPPYT00000018158; ENSPPYP00000017451; ENSPPYG00000015611
GeneIDi100189710
KEGGipon:100189710

Organism-specific databases

CTDi153339

Phylogenomic databases

eggNOGiKOG3808 Eukaryota
ENOG4112243 LUCA
GeneTreeiENSGT00860000133824
HOVERGENiHBG080265
InParanoidiQ5RAL1
OMAiFSILFMQ
OrthoDBiEOG091G15C1
TreeFamiTF300138

Family and domain databases

InterProiView protein in InterPro
IPR009653 Ksh1
PANTHERiPTHR13229 PTHR13229, 1 hit
PfamiView protein in Pfam
PF06842 DUF1242, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiKISHA_PONAB
AccessioniPrimary (citable) accession number: Q5RAL1
Secondary accession number(s): Q5RAC2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: December 21, 2004
Last modified: May 10, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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