We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - Q5R9U7 (BAP29_PONAB)
Protein
B-cell receptor-associated protein 29
Gene
BCAP29
Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Functioni
May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity).
By similarityGO - Biological processi
- apoptotic process Source: UniProtKB-KW
- intracellular protein transport Source: InterPro
- vesicle-mediated transport Source: UniProtKB-KW
Keywordsi
Biological process | Apoptosis, ER-Golgi transport, Protein transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: B-cell receptor-associated protein 29Short name: BCR-associated protein 29 Short name: Bap29 |
Gene namesi | Name:BCAP29 |
Organismi | Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
Taxonomic identifieri | 9601 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Pongo |
Proteomesi |
|
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane By similarity; Multi-pass membrane protein By similarity
Endoplasmic reticulum
- endoplasmic reticulum membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 6 | LumenalSequence analysis | 6 | |
Transmembranei | 7 – 27 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 28 – 43 | CytoplasmicSequence analysisAdd BLAST | 16 | |
Transmembranei | 44 – 64 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 65 – 103 | LumenalSequence analysisAdd BLAST | 39 | |
Transmembranei | 104 – 124 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 125 – 241 | CytoplasmicSequence analysisAdd BLAST | 117 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000142890 | 1 – 241 | B-cell receptor-associated protein 29Add BLAST | 241 |
Interactioni
Subunit structurei
Homodimer and heterodimer with BCAP31. Binds CASP8 as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1.
Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II (By similarity).
By similarityProtein-protein interaction databases
STRINGi | 9601.ENSPPYP00000020066 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 193 – 223 | DisorderedSequence analysisAdd BLAST | 31 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 166 – 233 | By similarityAdd BLAST | 68 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 238 – 241 | Di-lysine motif | 4 |
Sequence similaritiesi
Belongs to the BCAP29/BCAP31 family.Curated
Keywords - Domaini
Coiled coil, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1962, Eukaryota |
GeneTreei | ENSGT00390000011863 |
HOGENOMi | CLU_070975_1_0_1 |
InParanoidi | Q5R9U7 |
OMAi | FMARFWN |
OrthoDBi | 1514108at2759 |
TreeFami | TF315310 |
Family and domain databases
InterProi | View protein in InterPro IPR008417, BAP29/BAP31 IPR040463, BAP29/BAP31_N IPR041672, Bap31/Bap29_C |
PANTHERi | PTHR12701, PTHR12701, 1 hit |
Pfami | View protein in Pfam PF05529, Bap31, 1 hit PF18035, Bap31_Bap29_C, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5R9U7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTLQWAAVAT FLYAEIGLIL IFCLPFIPPQ RWQKIFSFNV WGKIATFWNK
60 70 80 90 100
AFLTIIILLI VLFLDAVREV RKYSSVHTIE KSSTSRPDAY EHTQMKLFRS
110 120 130 140 150
QRNLYISGFS LFFWLVLRRL VTLITQLAKE LSNKGVLKTQ AENTNKAAKK
160 170 180 190 200
FMEENEKLKR ILKSHGKDEE CVLEAENKKL VEDQQKLKTE LRKTSDALSK
210 220 230 240
AQNDVMEMKM QSERLSKEYD QLLKEHSELQ DRLERGNKKR L
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR858657 mRNA Translation: CAH90870.1 CR859285 mRNA Translation: CAH91463.1 |
RefSeqi | NP_001125860.1, NM_001132388.1 |
Genome annotation databases
Ensembli | ENSPPYT00000020858; ENSPPYP00000020066; ENSPPYG00000017902 |
GeneIDi | 100172790 |
KEGGi | pon:100172790 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR858657 mRNA Translation: CAH90870.1 CR859285 mRNA Translation: CAH91463.1 |
RefSeqi | NP_001125860.1, NM_001132388.1 |
3D structure databases
SMRi | Q5R9U7 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 9601.ENSPPYP00000020066 |
Genome annotation databases
Ensembli | ENSPPYT00000020858; ENSPPYP00000020066; ENSPPYG00000017902 |
GeneIDi | 100172790 |
KEGGi | pon:100172790 |
Organism-specific databases
CTDi | 55973 |
Phylogenomic databases
eggNOGi | KOG1962, Eukaryota |
GeneTreei | ENSGT00390000011863 |
HOGENOMi | CLU_070975_1_0_1 |
InParanoidi | Q5R9U7 |
OMAi | FMARFWN |
OrthoDBi | 1514108at2759 |
TreeFami | TF315310 |
Family and domain databases
InterProi | View protein in InterPro IPR008417, BAP29/BAP31 IPR040463, BAP29/BAP31_N IPR041672, Bap31/Bap29_C |
PANTHERi | PTHR12701, PTHR12701, 1 hit |
Pfami | View protein in Pfam PF05529, Bap31, 1 hit PF18035, Bap31_Bap29_C, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | BAP29_PONAB | |
Accessioni | Q5R9U7Primary (citable) accession number: Q5R9U7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 19, 2005 |
Last sequence update: | December 21, 2004 | |
Last modified: | February 23, 2022 | |
This is version 68 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families