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Entry version 45 (31 Jul 2019)
Sequence version 1 (21 Dec 2004)
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Protein
Submitted name:

Uncharacterized protein DKFZp469K026

Gene

DKFZp469K026

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized protein DKFZp469K026Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DKFZp469K026Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9601 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini175 – 249B-block_TFIIICInterPro annotationAdd BLAST75

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni467 – 521DisorderedSequence analysisAdd BLAST55
Regioni586 – 609DisorderedSequence analysisAdd BLAST24
Regioni718 – 775DisorderedSequence analysisAdd BLAST58
Regioni836 – 861DisorderedSequence analysisAdd BLAST26
Regioni1059 – 1082DisorderedSequence analysisAdd BLAST24
Regioni1202 – 1241DisorderedSequence analysisAdd BLAST40
Regioni1608 – 1628DisorderedSequence analysisAdd BLAST21
Regioni1824 – 1967DisorderedSequence analysisAdd BLAST144

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi479 – 496PolyampholyteSequence analysisAdd BLAST18
Compositional biasi497 – 515PolarSequence analysisAdd BLAST19
Compositional biasi718 – 734PolarSequence analysisAdd BLAST17
Compositional biasi744 – 760PolarSequence analysisAdd BLAST17
Compositional biasi838 – 852PolarSequence analysisAdd BLAST15
Compositional biasi1063 – 1082PolyampholyteSequence analysisAdd BLAST20
Compositional biasi1210 – 1229BasicSequence analysisAdd BLAST20
Compositional biasi1935 – 1949PolarSequence analysisAdd BLAST15

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4560 Eukaryota
ENOG410XSJ5 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154556

KEGG Orthology (KO)

More...
KOi
K15199

Database of Orthologous Groups

More...
OrthoDBi
143012at2759

Family and domain databases

Conserved Domains Database

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CDDi
cd16169 Tau138_eWH, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035625 Tfc3_eWH
IPR007309 TFIIIC_Bblock-bd

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04182 B-block_TFIIIC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5R9F7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDALESLLDE VALEGLDGLC LPALWSRLET RVPPFPLPLE PCTQEFLWRA
60 70 80 90 100
LATHPGISFY EEPRERPDLQ LQDRYEEIDL ETGILESRRD PVALEDVYPI
110 120 130 140 150
HMILENKDGI QGSCRYFKER KNITNDIRTK SLQPRCTMVE AFDRWGKKLI
160 170 180 190 200
IVASQAMRYR ALIGQEGDPD LKLPDFSYCI LERLGRSRWQ GELQRDLHTT
210 220 230 240 250
AFKVDAGKLH YHRKILNKNG LITMQSHVIR LPTGAQQHSI LLLLNRFHVD
260 270 280 290 300
RRSKYDILME KLSVMLSTRT NHIETLGKLR EELGLCERTF KRLYQHMLNA
310 320 330 340 350
GLAKVVSLRL QEIHPECGPC KTKKGTDVMV RCLKLLKEFK RNDHDDDEDE
360 370 380 390 400
EVISKTVPPV DIVFERDMLT QTYDLIERRG TKGISQAEIR VAMNVGKLEA
410 420 430 440 450
RMLCRLLQRF KVVKGFMEDE GRQRTTKYIS CVFAEESDLS RQYQREKARS
460 470 480 490 500
ELLTTVSLAS MQEESLLPEG EDTFLSESDS EEERSSSKRR GRGSQKDTRA
510 520 530 540 550
SANLRPKTQP HHSTPTKGGW KVVNLHPLKK QPPSFPGAAE ERACQSLASR
560 570 580 590 600
DNLLDTSNVS EPNVSFVSHC ADSNSGDIAV IEEVRVENPK ESSSSLKTGR
610 620 630 640 650
HSSSQDKPHE TYRLLKRRNL IIEAVTNLRL IESLFTIQKM IMDQEKQEGV
660 670 680 690 700
STKCCKKSIV RLVRNLSEEG LLRLYRTTVI QDGIKKKVDL VVHPSMDQND
710 720 730 740 750
PLVRSAIEQV RFRISNSSTA NGVKTSQPPV TQGEAEEDSQ GKEGPSGSGD
760 770 780 790 800
SQLSASSRSE SGRMKKSDNK MGITPLRNYH PIVVPGLGRS LGFLPKMPRL
810 820 830 840 850
RVVHMFLWYL IYGHPTSNTV EKPSFISERR TIKQESGRAG VRPSSSGSAW
860 870 880 890 900
EACSEAPSKG SQDGVTWEAE VELATETVYV DDASWMRYIP PLPVHRDFGF
910 920 930 940 950
GWALVSDILL CLPLSIFIQI VQVSYKVDNL EEFLNDPLKK HTLIRFLPRP
960 970 980 990 1000
IRQQLLYKRR YIFSVVENLQ RLCYMGLLQF GPTEKFQDKD QVFIFLKKNA
1010 1020 1030 1040 1050
VIVDTTTCDP HYNLARSSRP FERRLYVLNS MQDVENYWFD LQCVCLNTPL
1060 1070 1080 1090 1100
GVVRCPRVRK NSSTDQGSDE EGSLQKEQES AMDKHNLERK CAMLEYTTGS
1110 1120 1130 1140 1150
REVVDEGLIP GDGLGAAGLD SSFYGHLKRN WIWTSYIINQ AKKENTAAEN
1160 1170 1180 1190 1200
GLTVRLQTFL SKRPMPLSAR GNSRLNIWGE ARVGSELCAG WEEQFEVDRE
1210 1220 1230 1240 1250
PSLDRNRRVR GGKSQKRKRL KKDPGKKIKR RKKGEFPGEK SKRLRYHDEA
1260 1270 1280 1290 1300
DQSALQRMAR LRVTWSMQED GLLVLCRIAS NVLNTKVKGP FVTWQVVRDI
1310 1320 1330 1340 1350
LHATFEESLD KTSHSVGRRA RYIVKNPQAY LNYKVCLAEV YQDKALVGDF
1360 1370 1380 1390 1400
MNRRGDYDDP KVCANEFKEF VEKLKEKFSS ALRNSNLEIP DTLQELFARY
1410 1420 1430 1440 1450
RVLAIGDEKD QTRKEDELNS VDDIHFLVLQ NLIQSTLALS DSQMKSYQSF
1460 1470 1480 1490 1500
QTFRLYREYK DRVLVKAFME CQKRSLVNRR RVNHTLGPKK NRALPFVPMS
1510 1520 1530 1540 1550
YQLSQTYYRI FTWRFPSTIC TESFQFLDRM QAAGKLDQPD RFSFKDQDNN
1560 1570 1580 1590 1600
EPTNDMVAFS LDGPGGNCVA ILTLFSLGLI SVDVRIPEQI IVVDSSMVEN
1610 1620 1630 1640 1650
EVIKSLGKDG SLEDDEDEED DLDEGIGGKR RSMEVKPAQA SHTNYLLMRG
1660 1670 1680 1690 1700
YYSPGIVSTR NLNPNDSIVV NSCQMKFQLR CTPVPARLSP AAAPLEELTV
1710 1720 1730 1740 1750
GTSCLPDTFT KLINPQENTC SLEEFVLHLE PSGYSPEDLT AALEILEAII
1760 1770 1780 1790 1800
ATGCFGIDKE ELCRRFSALE KAGGGRTRTF ADCIQALLEQ HQVLEVGGNT
1810 1820 1830 1840 1850
ARLVAMGSAW PWLLHSVRLK DREDADIQRE DPQARPPEGS SSEDSPPEGQ
1860 1870 1880 1890 1900
APPSYSPRGT KRRASWASEN GETDAEGTQM TPAKRPVLQD SNLAPSLGPG
1910 1920 1930 1940 1950
AEDGAEAQAP SPPPALEDTA AAGSAREDQE GVGEFSSPGQ EQLSGQAQPP
1960 1970 1980 1990 2000
EGSEDPRGFT ESFGAGNISQ AARERDCESV CFIGRPWRVV DGHLNLPVCK
2010 2020 2030 2040 2050
GMMEAMLYHI MTRPGIPESC LLRHYQGVLQ PVAVLELLQG LESLGCIRKR
2060 2070 2080 2090 2100
WLRKPRPVLL FSTPVVEEVE VPSSLDESPM AFYEPTLDCT LRLGRVFPHE

VNWNKWIHL
Length:2,109
Mass (Da):238,790
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8EEA9A2371D83BA4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
CR859431 mRNA Translation: CAH91603.1

NCBI Reference Sequences

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RefSeqi
NP_001124552.1, NM_001131080.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
100127095

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pon:100127095

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR859431 mRNA Translation: CAH91603.1
RefSeqiNP_001124552.1, NM_001131080.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

GeneIDi100127095
KEGGipon:100127095

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
2975

Phylogenomic databases

eggNOGiKOG4560 Eukaryota
ENOG410XSJ5 LUCA
HOGENOMiHOG000154556
KOiK15199
OrthoDBi143012at2759

Family and domain databases

CDDicd16169 Tau138_eWH, 1 hit
InterProiView protein in InterPro
IPR035625 Tfc3_eWH
IPR007309 TFIIIC_Bblock-bd
PfamiView protein in Pfam
PF04182 B-block_TFIIIC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5R9F7_PONAB
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5R9F7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: July 31, 2019
This is version 45 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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