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Protein

60S ribosomal protein L35a

Gene

RPL35A

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, tRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L35a
Gene namesi
Name:RPL35A
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Chromosome 3

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001927991 – 11060S ribosomal protein L35aAdd BLAST110

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei8N6-acetyllysineBy similarity1
Modified residuei63N6-acetyllysine; alternateBy similarity1
Modified residuei63N6-succinyllysine; alternateBy similarity1

Keywords - PTMi

Acetylation

Interactioni

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000016170

Structurei

3D structure databases

ProteinModelPortaliQ5R8K6
SMRiQ5R8K6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0887 Eukaryota
COG2451 LUCA
GeneTreeiENSGT00390000016972
HOVERGENiHBG054581
InParanoidiQ5R8K6
KOiK02917
OMAiSTRLYSK
OrthoDBiEOG091G112U
TreeFamiTF300104

Family and domain databases

Gene3Di2.40.10.190, 1 hit
HAMAPiMF_00573 Ribosomal_L35Ae, 1 hit
InterProiView protein in InterPro
IPR038661 L35A_sf
IPR001780 Ribosomal_L35A
IPR018266 Ribosomal_L35Ae_CS
IPR009000 Transl_B-barrel_sf
PANTHERiPTHR10902 PTHR10902, 1 hit
PfamiView protein in Pfam
PF01247 Ribosomal_L35Ae, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD012670 Ribosomal_L35Ae, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
PROSITEiView protein in PROSITE
PS01105 RIBOSOMAL_L35AE, 1 hit

Sequencei

Sequence statusi: Complete.

Q5R8K6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGRLWSKAI FAGYKRGLRN QREHTALLKI EGVYARDETE FYLGKRCAYV
60 70 80 90 100
YKAKNNTVTP GGKPNKTRVI WGKVTRAHGN SGMVRAKFRS NLPAKAIGHR
110
IRVMLYPSRI
Length:110
Mass (Da):12,538
Last modified:December 21, 2004 - v1
Checksum:iF32E4A26A25E79E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR859746 mRNA Translation: CAH91904.1
RefSeqiNP_001126102.1, NM_001132630.1
XP_009237982.1, XM_009239707.1

Genome annotation databases

EnsembliENSPPYT00000016817; ENSPPYP00000016170; ENSPPYG00000014459
GeneIDi100173057
KEGGipon:100173057

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR859746 mRNA Translation: CAH91904.1
RefSeqiNP_001126102.1, NM_001132630.1
XP_009237982.1, XM_009239707.1

3D structure databases

ProteinModelPortaliQ5R8K6
SMRiQ5R8K6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000016170

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPPYT00000016817; ENSPPYP00000016170; ENSPPYG00000014459
GeneIDi100173057
KEGGipon:100173057

Organism-specific databases

CTDi6165

Phylogenomic databases

eggNOGiKOG0887 Eukaryota
COG2451 LUCA
GeneTreeiENSGT00390000016972
HOVERGENiHBG054581
InParanoidiQ5R8K6
KOiK02917
OMAiSTRLYSK
OrthoDBiEOG091G112U
TreeFamiTF300104

Family and domain databases

Gene3Di2.40.10.190, 1 hit
HAMAPiMF_00573 Ribosomal_L35Ae, 1 hit
InterProiView protein in InterPro
IPR038661 L35A_sf
IPR001780 Ribosomal_L35A
IPR018266 Ribosomal_L35Ae_CS
IPR009000 Transl_B-barrel_sf
PANTHERiPTHR10902 PTHR10902, 1 hit
PfamiView protein in Pfam
PF01247 Ribosomal_L35Ae, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD012670 Ribosomal_L35Ae, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
PROSITEiView protein in PROSITE
PS01105 RIBOSOMAL_L35AE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRL35A_PONAB
AccessioniPrimary (citable) accession number: Q5R8K6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: December 21, 2004
Last modified: November 7, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
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