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UniProtKB - Q5R3K3 (CAHM6_HUMAN)

Entry version 113 (02 Dec 2020)
Sequence version 1 (21 Dec 2004)
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Protein

Calcium homeostasis modulator protein 6

Gene

CALHM6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Pore-forming subunit of a voltage-gated ion channel.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • cation channel activity Source: GO_Central
Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channel
Biological processIon transport, Transport

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q5R3K3

Protein family/group databases

Transport Classification Database

More...TCDBi		1.A.84.1.6, the calcium homeostasis modulator ca(2+) channel (calhm-c) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Calcium homeostasis modulator protein 6
Alternative name(s):
Protein FAM26F
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CALHM6Imported
Synonyms:C6orf187, FAM26F
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000188820.12

Human Gene Nomenclature Database

More...HGNCi		HGNC:33391, CALHM6

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5R3K3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei19 – 39HelicalSequence analysisAdd BLAST21
Transmembranei52 – 72HelicalSequence analysisAdd BLAST21
Transmembranei104 – 124HelicalSequence analysisAdd BLAST21
Transmembranei176 – 196HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		441168

Open Targets

More...OpenTargetsi		ENSG00000188820

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162387644

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q5R3K3, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CALHM6

Domain mapping of disease mutations (DMDM)

More...DMDMi		74755904

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002837811 – 315Calcium homeostasis modulator protein 6Add BLAST315

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q5R3K3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q5R3K3

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5R3K3

PeptideAtlas

More...PeptideAtlasi		Q5R3K3

PRoteomics IDEntifications database

More...PRIDEi		Q5R3K3

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		63728 [Q5R3K3-1]
63729

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5R3K3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5R3K3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000188820, Expressed in spleen and 199 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q5R3K3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5R3K3, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000188820, Group enriched (blood, lymphoid tissue)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		137226, 3 interactors

Protein interaction database and analysis system

More...IntActi		Q5R3K3, 3 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000357594

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5R3K3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5R3K3

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CALHM family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QSG7, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT01000000214456

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_141357_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5R3K3

Identification of Orthologs from Complete Genome Data

More...OMAi		AVVFQCP

Database of Orthologous Groups

More...OrthoDBi		1039097at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5R3K3

TreeFam database of animal gene trees

More...TreeFami		TF329085

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029569, CALHM
IPR029573, CALHM6

The PANTHER Classification System

More...PANTHERi		PTHR32261, PTHR32261, 1 hit
PTHR32261:SF4, PTHR32261:SF4, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF14798, Ca_hom_mod, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5R3K3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEKFRAVLDL HVKHHSALGY GLVTLLTAGG ERIFSAVAFQ CPCSAAWNLP 
        60         70         80         90        100
YGLVFLLVPA LALFLLGYVL SARTWRLLTG CCSSARASCG SALRGSLVCT 
       110        120        130        140        150
QISAAAALAP LTWVAVALLG GAFYECAATG SAAFAQRLCL GRNRSCAAEL 
       160        170        180        190        200
PLVPCNQAKA SDVQDLLKDL KAQSQVLGWI LIAVVIIILL IFTSVTRCLS 
       210        220        230        240        250
PVSFLQLKFW KIYLEQEQQI LKSKATEHAT ELAKENIKCF FEGSHPKEYN 
       260        270        280        290        300
TPSMKEWQQI SSLYTFNPKG QYYSMLHKYV NRKEKTHSIR STEGDTVIPV 
       310 
LGFVDSSGIN STPEL
Length:315
Mass (Da):34,458
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i40059D0CD2D811E7
GO
Isoform 2 (identifier: Q5R3K3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-172: Missing.
     173-175: QSQ → MFP

Show »
Length:143
Mass (Da):16,490
Checksum:iBE4F3E587A32C7A5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5R3K2Q5R3K2_HUMAN
Calcium homeostasis modulator prote...
CALHM6
158Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05308580G → R. Corresponds to variant dbSNP:rs1057192Ensembl.1
Natural variantiVAR_071081100T → A2 PublicationsCorresponds to variant dbSNP:rs10784Ensembl.1
Natural variantiVAR_053086293E → K. Corresponds to variant dbSNP:rs11544160Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0556981 – 172Missing in isoform 2. CuratedAdd BLAST172
Alternative sequenceiVSP_055699173 – 175QSQ → MFP in isoform 2. Curated3

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
Z84488 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48228.1
BC146842 mRNA Translation: AAI46843.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS34519.1 [Q5R3K3-1]
CCDS64506.1 [Q5R3K3-2]

NCBI Reference Sequences

More...RefSeqi		NP_001010919.1, NM_001010919.2 [Q5R3K3-1]
NP_001263389.1, NM_001276460.1 [Q5R3K3-2]
XP_005267056.1, XM_005266999.3 [Q5R3K3-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000368605; ENSP00000357594; ENSG00000188820 [Q5R3K3-1]
ENST00000368606; ENSP00000357595; ENSG00000188820 [Q5R3K3-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		441168

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:441168

UCSC genome browser

More...UCSCi		uc003pwv.5, human [Q5R3K3-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z84488 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48228.1
BC146842 mRNA Translation: AAI46843.1
CCDSiCCDS34519.1 [Q5R3K3-1]
CCDS64506.1 [Q5R3K3-2]
RefSeqiNP_001010919.1, NM_001010919.2 [Q5R3K3-1]
NP_001263389.1, NM_001276460.1 [Q5R3K3-2]
XP_005267056.1, XM_005266999.3 [Q5R3K3-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6YTVelectron microscopy4.39A/B/C/D/E/F/G/H/I/J1-315[»]
6YTXelectron microscopy6.23A/B/C/D/E/F/G/H/I/J/K1-315[»]
SMRiQ5R3K3
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi137226, 3 interactors
IntActiQ5R3K3, 3 interactors
STRINGi9606.ENSP00000357594

Protein family/group databases

TCDBi1.A.84.1.6, the calcium homeostasis modulator ca(2+) channel (calhm-c) family

PTM databases

iPTMnetiQ5R3K3
PhosphoSitePlusiQ5R3K3

Polymorphism and mutation databases

BioMutaiCALHM6
DMDMi74755904

Proteomic databases

jPOSTiQ5R3K3
MassIVEiQ5R3K3
PaxDbiQ5R3K3
PeptideAtlasiQ5R3K3
PRIDEiQ5R3K3
ProteomicsDBi63728 [Q5R3K3-1]
63729

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		19421, 36 antibodies

Genome annotation databases

EnsembliENST00000368605; ENSP00000357594; ENSG00000188820 [Q5R3K3-1]
ENST00000368606; ENSP00000357595; ENSG00000188820 [Q5R3K3-2]
GeneIDi441168
KEGGihsa:441168
UCSCiuc003pwv.5, human [Q5R3K3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		441168
DisGeNETi441168
EuPathDBiHostDB:ENSG00000188820.12

GeneCards: human genes, protein and diseases

More...GeneCardsi		CALHM6
HGNCiHGNC:33391, CALHM6
HPAiENSG00000188820, Group enriched (blood, lymphoid tissue)
neXtProtiNX_Q5R3K3
OpenTargetsiENSG00000188820
PharmGKBiPA162387644

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QSG7, Eukaryota
GeneTreeiENSGT01000000214456
HOGENOMiCLU_141357_0_0_1
InParanoidiQ5R3K3
OMAiAVVFQCP
OrthoDBi1039097at2759
PhylomeDBiQ5R3K3
TreeFamiTF329085

Enzyme and pathway databases

PathwayCommonsiQ5R3K3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		441168, 3 hits in 838 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		FAM26F, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		441168
PharosiQ5R3K3, Tdark

Protein Ontology

More...PROi		PR:Q5R3K3
RNActiQ5R3K3, protein

Gene expression databases

BgeeiENSG00000188820, Expressed in spleen and 199 other tissues
ExpressionAtlasiQ5R3K3, baseline and differential
GenevisibleiQ5R3K3, HS

Family and domain databases

InterProiView protein in InterPro
IPR029569, CALHM
IPR029573, CALHM6
PANTHERiPTHR32261, PTHR32261, 1 hit
PTHR32261:SF4, PTHR32261:SF4, 1 hit
PfamiView protein in Pfam
PF14798, Ca_hom_mod, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCAHM6_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5R3K3
Secondary accession number(s): B9EJB0, Q5R3K4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: December 21, 2004
Last modified: December 2, 2020
This is version 113 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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