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UniProtKB - Q5R3F8 (PPR29_HUMAN)

Entry version 141 (23 Feb 2022)
Sequence version 1 (21 Dec 2004)
Previous versions | rss
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Protein

Protein phosphatase 1 regulatory subunit 29

Gene

ELFN2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionProtein phosphatase inhibitor

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q5R3F8

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q5R3F8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein phosphatase 1 regulatory subunit 29
Alternative name(s):
Extracellular leucine-rich repeat and fibronectin type III domain-containing protein 2
Leucine-rich repeat and fibronectin type-III domain-containing protein 6
Leucine-rich repeat-containing protein 62
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ELFN2
Synonyms:KIAA1904, LRRC62, PPP1R29
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:29396, ELFN2

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5R3F8

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000166897

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini23 – 397ExtracellularSequence analysisAdd BLAST375
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei398 – 418HelicalSequence analysisAdd BLAST21
Topological domaini419 – 820CytoplasmicSequence analysisAdd BLAST402

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		114794

Open Targets

More...OpenTargetsi		ENSG00000166897

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162385040

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q5R3F8, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ELFN2

Domain mapping of disease mutations (DMDM)

More...DMDMi		74755895

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 22Sequence analysisAdd BLAST22
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000025613823 – 820Protein phosphatase 1 regulatory subunit 29Add BLAST798

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi54N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi80N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi85N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi117N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi205N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi247N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei619PhosphoserineCombined sources1
Modified residuei668PhosphoserineBy similarity1
Modified residuei672PhosphoserineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q5R3F8

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q5R3F8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q5R3F8

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q5R3F8

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5R3F8

PeptideAtlas

More...PeptideAtlasi		Q5R3F8

PRoteomics IDEntifications database

More...PRIDEi		Q5R3F8

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		63725

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q5R3F8, 7 sites

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5R3F8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5R3F8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000166897, Expressed in brain and 114 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5R3F8, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000166897, Group enriched (brain, retina)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PPP1CA.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		125356, 18 interactors

Protein interaction database and analysis system

More...IntActi		Q5R3F8, 2 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000385277

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5R3F8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5R3F8

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati56 – 77LRR 1Add BLAST22
Repeati80 – 101LRR 2Add BLAST22
Repeati104 – 125LRR 3Add BLAST22
Repeati128 – 149LRR 4Add BLAST22
Repeati152 – 173LRR 5Add BLAST22
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini185 – 247LRRCTAdd BLAST63
Domaini292 – 379Fibronectin type-IIIAdd BLAST88

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni250 – 294DisorderedSequence analysisAdd BLAST45
Regioni508 – 527DisorderedSequence analysisAdd BLAST20
Regioni589 – 612DisorderedSequence analysisAdd BLAST24
Regioni654 – 677DisorderedSequence analysisAdd BLAST24

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QVFI, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159737

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_018770_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5R3F8

Identification of Orthologs from Complete Genome Data

More...OMAi		MAFECQS

Database of Orthologous Groups

More...OrthoDBi		190870at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5R3F8

TreeFam database of animal gene trees

More...TreeFami		TF332887

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001611, Leu-rich_rpt
IPR003591, Leu-rich_rpt_typical-subtyp
IPR032675, LRR_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13855, LRR_8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00369, LRR_TYP, 4 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51450, LRR, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q5R3F8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRLGLCAAA LLCVCRPGAV RADCWLIEGD KGYVWLAICS QNQPPYETIP 
        60         70         80         90        100
QHINSTVHDL RLNENKLKAV LYSSLNRFGN LTDLNLTKNE ISYIEDGAFL 
       110        120        130        140        150
GQSSLQVLQL GYNKLSNLTE GMLRGMSRLQ FLFVQHNLIE VVTPTAFSEC 
       160        170        180        190        200
PSLISIDLSS NRLSRLDGAT FASLASLMVC ELAGNPFNCE CDLFGFLAWL 
       210        220        230        240        250
VVFNNVTKNY DRLQCESPRE FAGYPLLVPR PYHSLNAITV LQAKCRNGSL 
       260        270        280        290        300
PARPVSHPTP YSTDAQREPD ENSGFNPDEI LSVEPPASST TDASAGPAIK 
       310        320        330        340        350
LHHVTFTSAT LVVIIPHPYS KMYILVQYNN SYFSDVMTLK NKKEIVTLDK 
       360        370        380        390        400
LRAHTEYTFC VTSLRNSRRF NHTCLTFTTR DPVPGDLAPS TSTTTHYIMT 
       410        420        430        440        450
ILGCLFGMVI VLGAVYYCLR KRRMQEEKQK SVNVKKTILE MRYGADVDAG 
       460        470        480        490        500
SIVHAAQKLG EPPVLPVSRM ASIPSMIGEK LPTAKGLEAG LDTPKVATKG 
       510        520        530        540        550
NYIEVRTGAG GDGLARPEDD LPDLENGQGS AAEISTIAKE VDKVNQIINN 
       560        570        580        590        600
CIDALKLDSA SFLGGGSSSG DPELAFECQS LPAAAAASSA TGPGALERPS 
       610        620        630        640        650
FLSPPYKESS HHPLQRQLSA DAAVTRKTCS VSSSGSIKSA KVFSLDVPDH 
       660        670        680        690        700
PAATGLAKGD SKYIEKGSPL NSPLDRLPLV PAGSGGGSGG GGGIHHLEVK 
       710        720        730        740        750
PAYHCSEHRH SFPALYYEEG ADSLSQRVSF LKPLTRSKRD STYSQLSPRH 
       760        770        780        790        800
YYSGYSSSPE YSSESTHKIW ERFRPYKKHH REEVYMAAGH ALRKKVQFAK 
       810        820
DEDLHDILDY WKGVSAQQKL
Length:820
Mass (Da):89,687
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i18BCDBDEC0F21212
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB67797 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti239T → I in BAB67797 (PubMed:11572484).Curated1
Sequence conflicti605P → S in BAB67797 (PubMed:11572484).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB067491 mRNA Translation: BAB67797.1 Different initiation.
Z94160 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS33642.1

NCBI Reference Sequences

More...RefSeqi		NP_443138.2, NM_052906.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000402918; ENSP00000385277; ENSG00000166897

Database of genes from NCBI RefSeq genomes

More...GeneIDi		114794

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:114794

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000402918.7; ENSP00000385277.1; NM_052906.5; NP_443138.2

UCSC genome browser

More...UCSCi		uc003asq.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB067491 mRNA Translation: BAB67797.1 Different initiation.
Z94160 Genomic DNA No translation available.
CCDSiCCDS33642.1
RefSeqiNP_443138.2, NM_052906.4

3D structure databases

SMRiQ5R3F8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi125356, 18 interactors
IntActiQ5R3F8, 2 interactors
STRINGi9606.ENSP00000385277

PTM databases

GlyGeniQ5R3F8, 7 sites
iPTMnetiQ5R3F8
PhosphoSitePlusiQ5R3F8

Genetic variation databases

BioMutaiELFN2
DMDMi74755895

Proteomic databases

EPDiQ5R3F8
jPOSTiQ5R3F8
MassIVEiQ5R3F8
MaxQBiQ5R3F8
PaxDbiQ5R3F8
PeptideAtlasiQ5R3F8
PRIDEiQ5R3F8
ProteomicsDBi63725

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		274, 63 antibodies from 16 providers

The DNASU plasmid repository

More...DNASUi		114794

Genome annotation databases

EnsembliENST00000402918; ENSP00000385277; ENSG00000166897
GeneIDi114794
KEGGihsa:114794
MANE-SelectiENST00000402918.7; ENSP00000385277.1; NM_052906.5; NP_443138.2
UCSCiuc003asq.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		114794
DisGeNETi114794

GeneCards: human genes, protein and diseases

More...GeneCardsi		ELFN2
HGNCiHGNC:29396, ELFN2
HPAiENSG00000166897, Group enriched (brain, retina)
neXtProtiNX_Q5R3F8
OpenTargetsiENSG00000166897
PharmGKBiPA162385040
VEuPathDBiHostDB:ENSG00000166897

Human Unidentified Gene-Encoded large proteins database

More...HUGEi		Search...

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QVFI, Eukaryota
GeneTreeiENSGT00940000159737
HOGENOMiCLU_018770_0_0_1
InParanoidiQ5R3F8
OMAiMAFECQS
OrthoDBi190870at2759
PhylomeDBiQ5R3F8
TreeFamiTF332887

Enzyme and pathway databases

PathwayCommonsiQ5R3F8
SignaLinkiQ5R3F8

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		114794, 7 hits in 1033 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ELFN2, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		114794
PharosiQ5R3F8, Tdark

Protein Ontology

More...PROi		PR:Q5R3F8
RNActiQ5R3F8, protein

Gene expression databases

BgeeiENSG00000166897, Expressed in brain and 114 other tissues
GenevisibleiQ5R3F8, HS

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR001611, Leu-rich_rpt
IPR003591, Leu-rich_rpt_typical-subtyp
IPR032675, LRR_dom_sf
PfamiView protein in Pfam
PF13855, LRR_8, 1 hit
SMARTiView protein in SMART
SM00369, LRR_TYP, 4 hits
PROSITEiView protein in PROSITE
PS51450, LRR, 4 hits

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPPR29_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5R3F8
Secondary accession number(s): Q96PY3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: December 21, 2004
Last modified: February 23, 2022
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
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