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Protein
Submitted name:

Sorting nexin-5

Gene

SNX5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Sorting nexin-5Imported
Gene namesi
Name:SNX5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000089006.16
HGNCiHGNC:14969 SNX5

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000089006

PTM / Processingi

Proteomic databases

PeptideAtlasiQ5QPE4
PRIDEiQ5QPE4

Expressioni

Gene expression databases

BgeeiENSG00000089006 Expressed in 221 organ(s), highest expression level in adrenal tissue
ExpressionAtlasiQ5QPE4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5QPE4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 137PXInterPro annotationAdd BLAST137

Phylogenomic databases

GeneTreeiENSGT00930000150924
HOGENOMiHOG000231691
HOVERGENiHBG000716

Family and domain databases

Gene3Di1.20.1270.60, 1 hit
3.30.1520.10, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR001683 Phox
IPR036871 PX_dom_sf
IPR028654 SNX5
IPR039358 Sorting_nexin-like
PANTHERiPTHR10555 PTHR10555, 1 hit
PTHR10555:SF6 PTHR10555:SF6, 1 hit
PfamiView protein in Pfam
PF00787 PX, 1 hit
SUPFAMiSSF64268 SSF64268, 1 hit
PROSITEiView protein in PROSITE
PS50195 PX, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q5QPE4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAVPELLQQ QEEDRSKTTL PTFQSPEFSV TRQHEDFVWL HDTLIETTDY
60 70 80 90 100
AGLIIPPAPT KPDFDGPREK MQKLGEGEGS MTKEEFAKMK QELEAEYLAV
110 120 130 140 150
FKKTVSSHEV FLQRLSSHPV LSKDRNFHVF LEYDQDLSVR RKNTKEMFGG
160 170 180 190 200
FFKSVVKSAD EVLFTGVKEV DDFFEQEKNF LINYYNRIKD SCVKADKMTR
210 220 230
SHKNVADDYI HTAACLHSLA LEEPTVIKKY
Length:230
Mass (Da):26,596
Last modified:October 5, 2016 - v7
Checksum:i506E243D29B720F1
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9Y5X3SNX5_HUMAN
Sorting nexin-5
SNX5
404Annotation score:
Q5QPE5Q5QPE5_HUMAN
Sorting nexin-5
SNX5
269Annotation score:
A0A087WUY5A0A087WUY5_HUMAN
Sorting nexin-5
SNX5
170Annotation score:
U3KQL0U3KQL0_HUMAN
Sorting nexin 5 isoform 2
SNX5
31Annotation score:
U3KQP5U3KQP5_HUMAN
Sorting nexin-5
SNX5
55Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei230Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121585 Genomic DNA No translation available.
KF511290 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000419004; ENSP00000406731; ENSG00000089006
UCSCiuc061voq.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121585 Genomic DNA No translation available.
KF511290 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliQ5QPE4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ5QPE4
PRIDEiQ5QPE4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000419004; ENSP00000406731; ENSG00000089006
UCSCiuc061voq.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000089006.16
HGNCiHGNC:14969 SNX5
OpenTargetsiENSG00000089006
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00930000150924
HOGENOMiHOG000231691
HOVERGENiHBG000716

Miscellaneous databases

ChiTaRSiSNX5 human

Gene expression databases

BgeeiENSG00000089006 Expressed in 221 organ(s), highest expression level in adrenal tissue
ExpressionAtlasiQ5QPE4 baseline and differential

Family and domain databases

Gene3Di1.20.1270.60, 1 hit
3.30.1520.10, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR001683 Phox
IPR036871 PX_dom_sf
IPR028654 SNX5
IPR039358 Sorting_nexin-like
PANTHERiPTHR10555 PTHR10555, 1 hit
PTHR10555:SF6 PTHR10555:SF6, 1 hit
PfamiView protein in Pfam
PF00787 PX, 1 hit
SUPFAMiSSF64268 SSF64268, 1 hit
PROSITEiView protein in PROSITE
PS50195 PX, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5QPE4_HUMAN
AccessioniPrimary (citable) accession number: Q5QPE4
Entry historyiIntegrated into UniProtKB/TrEMBL: January 4, 2005
Last sequence update: October 5, 2016
Last modified: November 7, 2018
This is version 97 of the entry and version 7 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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