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UniProtKB - Q5QP59 (Q5QP59_HUMAN)
Protein
Submitted name:
Bcl-2-like protein 1
Gene
BCL2L1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- apoptotic process Source: UniProtKB-UniRule
- regulation of apoptotic process Source: InterPro
Keywordsi
Biological process | ApoptosisPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Bcl-2-like protein 1Imported |
Gene namesi | Name:BCL2L1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:992, BCL2L1 |
VEuPathDBi | HostDB:ENSG00000171552 |
Expressioni
Gene expression databases
Bgeei | ENSG00000171552, Expressed in upper lobe of left lung and 238 other tissues |
ExpressionAtlasi | Q5QP59, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 5 – 24 | BH4_2InterPro annotationAdd BLAST | 20 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 27 – 48 | DisorderedSequence analysisAdd BLAST | 22 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 5 – 24 | BH4PROSITE-ProRule annotationAdd BLAST | 20 |
Phylogenomic databases
GeneTreei | ENSGT01020000230347 |
HOGENOMi | CLU_3162360_0_0_1 |
Family and domain databases
Gene3Di | 1.10.437.10, 1 hit |
InterProi | View protein in InterPro IPR013279, Apop_reg_BclX IPR036834, Bcl-2-like_sf IPR026298, Bcl-2_fam IPR003093, Bcl2_BH4 IPR020731, Bcl2_BH4_motif_CS |
PANTHERi | PTHR11256, PTHR11256, 1 hit PTHR11256:SF12, PTHR11256:SF12, 1 hit |
Pfami | View protein in Pfam PF02180, BH4, 1 hit |
PRINTSi | PR01864, APOPREGBCLX |
SMARTi | View protein in SMART SM00265, BH4, 1 hit |
SUPFAMi | SSF56854, SSF56854, 1 hit |
PROSITEi | View protein in PROSITE PS01260, BH4_1, 1 hit PS50063, BH4_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
Q5QP59-1 [UniParc]FASTAAdd to basket
10 20 30 40
MSQSNRELVV DFLSYKLSQK GYSWSQFSDV EENRTEAPEG TESEMETP
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ07817 | B2CL1_HUMAN | Bcl-2-like protein 1 | BCL2L1 BCL2L, BCLX | 233 | Annotation score: | ||
Q5TE64 | Q5TE64_HUMAN | Bcl-2-like protein 1 | BCL2L1 | 307 | Annotation score: | ||
Q5QP56 | Q5QP56_HUMAN | Bcl-2-like protein 1 | BCL2L1 | 181 | Annotation score: | ||
Q9H1R6 | Q9H1R6_HUMAN | Bcl-2-like protein 1 | BCL2L1 | 188 | Annotation score: | ||
A0A7I2V597 | A0A7I2V597_HUMAN | Bcl-2-like protein 1 | BCL2L1 | 200 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 48 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL117381 Genomic DNA No translation available. AL160175 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000434194; ENSP00000401173; ENSG00000171552 |
UCSCi | uc061wcs.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL117381 Genomic DNA No translation available. AL160175 Genomic DNA No translation available. |
3D structure databases
SMRi | Q5QP59 |
ModBasei | Search... |
Proteomic databases
MaxQBi | Q5QP59 |
PeptideAtlasi | Q5QP59 |
ProteomicsDBi | 63637 |
Protocols and materials databases
Antibodypediai | 3430, 2000 antibodies from 52 providers |
Genome annotation databases
Ensembli | ENST00000434194; ENSP00000401173; ENSG00000171552 |
UCSCi | uc061wcs.1, human |
Organism-specific databases
HGNCi | HGNC:992, BCL2L1 |
OpenTargetsi | ENSG00000171552 |
VEuPathDBi | HostDB:ENSG00000171552 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT01020000230347 |
HOGENOMi | CLU_3162360_0_0_1 |
Miscellaneous databases
ChiTaRSi | BCL2L1, human |
Gene expression databases
Bgeei | ENSG00000171552, Expressed in upper lobe of left lung and 238 other tissues |
ExpressionAtlasi | Q5QP59, baseline and differential |
Family and domain databases
Gene3Di | 1.10.437.10, 1 hit |
InterProi | View protein in InterPro IPR013279, Apop_reg_BclX IPR036834, Bcl-2-like_sf IPR026298, Bcl-2_fam IPR003093, Bcl2_BH4 IPR020731, Bcl2_BH4_motif_CS |
PANTHERi | PTHR11256, PTHR11256, 1 hit PTHR11256:SF12, PTHR11256:SF12, 1 hit |
Pfami | View protein in Pfam PF02180, BH4, 1 hit |
PRINTSi | PR01864, APOPREGBCLX |
SMARTi | View protein in SMART SM00265, BH4, 1 hit |
SUPFAMi | SSF56854, SSF56854, 1 hit |
PROSITEi | View protein in PROSITE PS01260, BH4_1, 1 hit PS50063, BH4_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5QP59_HUMAN | |
Accessioni | Q5QP59Primary (citable) accession number: Q5QP59 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 4, 2005 |
Last sequence update: | January 4, 2005 | |
Last modified: | January 19, 2022 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |