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Entry version 124 (17 Jun 2020)
Sequence version 2 (16 Aug 2005)
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Protein

Two pore calcium channel protein 1

Gene

TPC1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane. May be involved in the regulation of cytosolic Ca2+ and in growth and development. Acts as the major ROS-responsive Ca2+ channel and is the possible target of Al-dependent inhibition. Determines sensitivity to T.viride xylanase elicitor. Plays a regulatory role in elicitor-induced defense responses and hypersensitive cell death.3 Publications

Miscellaneous

Rescues the Ca2+ uptake activity in yeast mutant cch1. Plants overexpressing TPC1 display reduced growth rate and dwarf phenotype, and seedlings show greening of roots under light conditions. The highest overexpressor line shows most severe phenotype including a death symptom, possibily due to Ca2+ accumulation to toxic level.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by the VDCC blocker verapamil in yeast cells. Channel activity may be down-regulated by cytosolic Ca2+ in rice cells. Inhibited by Al3+ (By similarity).By similarity

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

Measured in yeast knockout mutant cch1.
  1. KM=47.5 µM for Ca2+ (at 30 degrees Celsius)1 Publication

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionCalcium channel, Ion channel, Voltage-gated channel
    Biological processCalcium transport, Ion transport, Plant defense, Transport
    LigandCalcium

    Protein family/group databases

    Transport Classification Database

    More...
    TCDBi
    1.A.1.11.13 the voltage-gated ion channel (vic) superfamily

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Two pore calcium channel protein 1
    Alternative name(s):
    OsTPC1
    Voltage-dependent calcium channel protein TPC1
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:TPC1
    Ordered Locus Names:Os01g0678500, LOC_Os01g48680
    ORF Names:B1144G04.26-1, OsJ_03004Imported
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000007752 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1
    • UP000059680 Componenti: Chromosome 1
    • UP000000763 Componenti: Chromosome 1

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 94CytoplasmicSequence analysisAdd BLAST94
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei95 – 115Helical; Name=S1 of repeat ISequence analysisAdd BLAST21
    Topological domaini116 – 152ExtracellularSequence analysisAdd BLAST37
    Transmembranei153 – 173Helical; Name=S2 of repeat ISequence analysisAdd BLAST21
    Topological domaini174 – 188CytoplasmicSequence analysisAdd BLAST15
    Transmembranei189 – 209Helical; Name=S3 of repeat ISequence analysisAdd BLAST21
    Topological domaini210ExtracellularSequence analysis1
    Transmembranei211 – 228Helical; Voltage-sensor; Name=S4 of repeat ISequence analysisAdd BLAST18
    Topological domaini229 – 233CytoplasmicSequence analysis5
    Transmembranei234 – 254Helical; Name=S5 of repeat ISequence analysisAdd BLAST21
    Topological domaini255 – 270ExtracellularSequence analysisAdd BLAST16
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a region that is buried within a membrane, but does not cross it.<p><a href='/help/intramem' target='_top'>More...</a></p>Intramembranei271 – 285Pore-forming; Name=Pore-forming 1Add BLAST15
    Topological domaini286 – 308ExtracellularSequence analysisAdd BLAST23
    Transmembranei309 – 329Helical; Name=S6 of repeat ISequence analysisAdd BLAST21
    Topological domaini330 – 453CytoplasmicSequence analysisAdd BLAST124
    Transmembranei454 – 474Helical; Name=S1 of repeat IISequence analysisAdd BLAST21
    Topological domaini475 – 493ExtracellularSequence analysisAdd BLAST19
    Transmembranei494 – 514Helical; Name=S2 of repeat IISequence analysisAdd BLAST21
    Topological domaini515 – 523CytoplasmicSequence analysis9
    Transmembranei524 – 544Helical; Name=S3 of repeat IISequence analysisAdd BLAST21
    Topological domaini545 – 553ExtracellularSequence analysis9
    Transmembranei554 – 571Helical; Voltage-sensor; Name=S4 of repeat IISequence analysisAdd BLAST18
    Topological domaini572 – 595CytoplasmicSequence analysisAdd BLAST24
    Transmembranei596 – 616Helical; Name=S5 of repeat IISequence analysisAdd BLAST21
    Topological domaini617 – 640ExtracellularSequence analysisAdd BLAST24
    Intramembranei641 – 655Pore-forming; Name=Pore-forming 2Add BLAST15
    Topological domaini656 – 676ExtracellularSequence analysisAdd BLAST21
    Transmembranei677 – 697Helical; Name=S6 of repeat IISequence analysisAdd BLAST21
    Topological domaini698 – 757CytoplasmicSequence analysisAdd BLAST60

    Keywords - Cellular componenti

    Membrane

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000539621 – 757Two pore calcium channel protein 1Add BLAST757

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi482N-linked (GlcNAc...) asparagineSequence analysis1

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q5QM84

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q5QM84

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Expressed in shoot, mature leaf, cultured cells, and at lower level in roots.1 Publication

    Gene expression databases

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q5QM84 OS

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    Homodimer.

    Curated

    GO - Molecular functioni

    Protein-protein interaction databases

    STRING: functional protein association networks

    More...
    STRINGi
    4530.OS01T0678500-02

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini347 – 382EF-hand 1PROSITE-ProRule annotationAdd BLAST36
    Domaini388 – 423EF-hand 2PROSITE-ProRule annotationAdd BLAST36

    <p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

    Each of the two internal repeats contains five hydrophobic transmembrane segments (S1, S2, S3, S5, S6) and one positively charged transmembrane segment (S4). S4 segments probably represent the voltage-sensor and are characterized by a series of positively charged amino acids (By similarity).By similarity

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    ENOG410INF7 Eukaryota
    ENOG410XZT8 LUCA

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    CLU_426053_0_0_1

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q5QM84

    KEGG Orthology (KO)

    More...
    KOi
    K16900

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    YIRVAFL

    Database of Orthologous Groups

    More...
    OrthoDBi
    761764at2759

    Family and domain databases

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    1.20.120.350, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR011992 EF-hand-dom_pair
    IPR002048 EF_hand_dom
    IPR005821 Ion_trans_dom
    IPR027359 Volt_channel_dom_sf

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF00520 Ion_trans, 2 hits

    Simple Modular Architecture Research Tool; a protein domain database

    More...
    SMARTi
    View protein in SMART
    SM00054 EFh, 2 hits

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF47473 SSF47473, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS50222 EF_HAND_2, 2 hits

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    Q5QM84-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MRERGEMREA KAPLIAEAAE HISHSHGSGS SGTGSHTSGG GGGWRGSRQY
    60 70 80 90 100
    QRRSDALAYG NRYQKAAALV DLAEDGVGIP EDVLNDTRFE RAMRFYFVYL
    110 120 130 140 150
    RLDWLWSLNL FALILLNFLE KPLWCRGYSQ HACDQRDLYF LGQLPYLSKT
    160 170 180 190 200
    ESLIYEGLTL VILVMDIFYP LSYEGLNLFW KNTINKLKVL LLFILACDIL
    210 220 230 240 250
    VFAFSPQPFR VAPYIRVAFL IMNIRELRMC AVTLVGMVGT YLNVLALSLL
    260 270 280 290 300
    FLLFASWLAY VTFEDTPQGK TVFSSYGTTL YQMFILFTTS NNPDVWVPAY
    310 320 330 340 350
    KSSRWSSLFF IVYVLLGVYF LTNLILAVIY DSFKEQLAKQ VSQADCTRKS
    360 370 380 390 400
    ILEKAFGIID ATGQGYLNKE QCLSLLDELN KYRSLPKTSR EDFELIFAEL
    410 420 430 440 450
    DQSGDFKVTS EEFATLCNTI AIKFQKEPPP SYLEKYPSFY HSALCEWLKS
    460 470 480 490 500
    FVRSPLFEYI VIFVLLMNLV AVIIETTLDI ENSSSQKVWQ EVEFVFGWIY
    510 520 530 540 550
    VIEMALKIFS LGFGAYWMEG QNKFDFVLTW TIFIGETLTF AFPSKLSFLS
    560 570 580 590 600
    NGEWIRYLLL GRMLRLTRIL LQVRRFRAFV ATFFTLMSSL MPYLGIVFCT
    610 620 630 640 650
    LCIYCSLGLQ IFGGIVYAGN PTLEETDLFS NDYLLFNFND YPSGMVTLFN
    660 670 680 690 700
    LLVMGNWQAW MESYRQLTGS YWSLIYFVSF YLISVLLLLN LIVAFVLEAF
    710 720 730 740 750
    FAEMELEKDG EADIQDPTLE GRNRRRSVRV RTKGTMVDIL LHHMLSNELD

    GSQNRDQ
    Length:757
    Mass (Da):87,069
    Last modified:August 16, 2005 - v2
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE12332F4E1A493BC
    GO

    <p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence BAD73470 differs from that shown. Reason: Erroneous gene model prediction.Curated

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti554W → L in BAC80148 (PubMed:15111725).Curated1

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AB100696 mRNA Translation: BAC80148.1
    AB071014 mRNA Translation: BAC78525.1
    AP003335 Genomic DNA Translation: BAD73469.1
    AP003335 Genomic DNA Translation: BAD73470.1 Sequence problems.
    AP008207 Genomic DNA Translation: BAF05772.1
    AP014957 Genomic DNA Translation: BAS73676.1
    CM000138 Genomic DNA Translation: EEE55175.1

    NCBI Reference Sequences

    More...
    RefSeqi
    XP_015621659.1, XM_015766173.1

    Genome annotation databases

    Ensembl plant genome annotation project

    More...
    EnsemblPlantsi
    Os01t0678500-01; Os01t0678500-01; Os01g0678500
    Os01t0678500-02; Os01t0678500-02; Os01g0678500

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    4325272

    Gramene; a comparative resource for plants

    More...
    Gramenei
    Os01t0678500-01; Os01t0678500-01; Os01g0678500
    Os01t0678500-02; Os01t0678500-02; Os01g0678500

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    osa:4325272

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AB100696 mRNA Translation: BAC80148.1
    AB071014 mRNA Translation: BAC78525.1
    AP003335 Genomic DNA Translation: BAD73469.1
    AP003335 Genomic DNA Translation: BAD73470.1 Sequence problems.
    AP008207 Genomic DNA Translation: BAF05772.1
    AP014957 Genomic DNA Translation: BAS73676.1
    CM000138 Genomic DNA Translation: EEE55175.1
    RefSeqiXP_015621659.1, XM_015766173.1

    3D structure databases

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    SWISS-MODEL Interactive Workspace

    More...
    SWISS-MODEL-Workspacei
    Submit a new modelling project...

    Protein-protein interaction databases

    STRINGi4530.OS01T0678500-02

    Protein family/group databases

    TCDBi1.A.1.11.13 the voltage-gated ion channel (vic) superfamily

    Proteomic databases

    PaxDbiQ5QM84
    PRIDEiQ5QM84

    Genome annotation databases

    EnsemblPlantsiOs01t0678500-01; Os01t0678500-01; Os01g0678500
    Os01t0678500-02; Os01t0678500-02; Os01g0678500
    GeneIDi4325272
    GrameneiOs01t0678500-01; Os01t0678500-01; Os01g0678500
    Os01t0678500-02; Os01t0678500-02; Os01g0678500
    KEGGiosa:4325272

    Phylogenomic databases

    eggNOGiENOG410INF7 Eukaryota
    ENOG410XZT8 LUCA
    HOGENOMiCLU_426053_0_0_1
    InParanoidiQ5QM84
    KOiK16900
    OMAiYIRVAFL
    OrthoDBi761764at2759

    Gene expression databases

    GenevisibleiQ5QM84 OS

    Family and domain databases

    Gene3Di1.20.120.350, 1 hit
    InterProiView protein in InterPro
    IPR011992 EF-hand-dom_pair
    IPR002048 EF_hand_dom
    IPR005821 Ion_trans_dom
    IPR027359 Volt_channel_dom_sf
    PfamiView protein in Pfam
    PF00520 Ion_trans, 2 hits
    SMARTiView protein in SMART
    SM00054 EFh, 2 hits
    SUPFAMiSSF47473 SSF47473, 1 hit
    PROSITEiView protein in PROSITE
    PS50222 EF_HAND_2, 2 hits

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTPC1_ORYSJ
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5QM84
    Secondary accession number(s): B9EYL2
    , Q0JKF6, Q5QM85, Q7XB54, Q7XXT1
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
    Last sequence update: August 16, 2005
    Last modified: June 17, 2020
    This is version 124 of the entry and version 2 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
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