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Entry version 111 (02 Dec 2020)
Sequence version 1 (04 Jan 2005)
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Protein

Sodium/bile acid cotransporter 7

Gene

Slc10a7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization (PubMed:30082715). Also involved in the regulation of cellular calcium homeostasis (By similarity). Does not show transport activity towards bile acids or steroid sulfates (including taurocholate, cholate, chenodeoxycholate, estrone-3-sulfate, dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate).By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Sodium transport, Symport, Transport
LigandSodium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sodium/bile acid cotransporter 7
Alternative name(s):
Na(+)/bile acid cotransporter 7
Solute carrier family 10 member 7
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Slc10a7
Synonyms:P7
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1924025, Slc10a7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 10CytoplasmicBy similarity10
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei11 – 31HelicalSequence analysisAdd BLAST21
Topological domaini32 – 37ExtracellularBy similarity6
Transmembranei38 – 58HelicalSequence analysisAdd BLAST21
Topological domaini59 – 71CytoplasmicBy similarityAdd BLAST13
Transmembranei72 – 92HelicalSequence analysisAdd BLAST21
Topological domaini93 – 116ExtracellularBy similarityAdd BLAST24
Transmembranei117 – 137HelicalSequence analysisAdd BLAST21
Topological domaini138CytoplasmicBy similarity1
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Topological domaini160 – 163ExtracellularBy similarity4
Transmembranei164 – 184HelicalSequence analysisAdd BLAST21
Topological domaini185 – 201CytoplasmicBy similarityAdd BLAST17
Transmembranei202 – 222HelicalSequence analysisAdd BLAST21
Topological domaini223 – 234ExtracellularBy similarityCuratedAdd BLAST12
Transmembranei235 – 255HelicalSequence analysisAdd BLAST21
Topological domaini256 – 270CytoplasmicBy similarityAdd BLAST15
Transmembranei271 – 291HelicalSequence analysisAdd BLAST21
Topological domaini292 – 298ExtracellularBy similarity7
Transmembranei299 – 319HelicalSequence analysisAdd BLAST21
Topological domaini320 – 340CytoplasmicBy similarityAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Endoplasmic reticulum, Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Knockout mice present with skeletal dysplasia including growth retardation at birth and at 8 weeks, alteration of long-bone morphology, craniofacial anomalies and advanced tarsal maturation at birth, associated with enamel defects. The proportion of heparan sulfate (HS) in cartilage of knockout mice is significantly reduced compared with wild-type animals. SLC10A7 deficiency has no impact on skeletal muscle heparan sulfate levels.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002782511 – 340Sodium/bile acid cotransporter 7Add BLAST340

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5PT53

PRoteomics IDEntifications database

More...
PRIDEi
Q5PT53

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5PT53

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in heart, brain, colon, lung, liver, adrenal gland, stomach and ovary. Also expressed weakly in small intestine. Expressed in skeletal tissues (PubMed:30082715).2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Embryos at gestational age E12.5 show the weakest SLC10A7 expression, mainly in the heart trabeculae of the developing heart and the cartilage of the vertebrae. From day E14.5 onwards, expression becomes more ubiquitous, with the strongest level observed at day E16.5 and postnatal day P0. At E14.5, it is strongly expressed in cartilaginous structures in the mandible, in the epithelial compartment of cap stage teeth, in the digits, in the spine and in the lung. At E16.5, transcripts are mostly localized in the inner dental epithelium and in the epithelial loop of bell stage teeth. At E18.5 expression is observed in the inner dental epithelium of incisors, and in ameloblasts and odontoblasts of molars. At postnatal day P0 there is strong expression in the papillary layer of the oral mucous membrane underneath the palate, as well as in the ameloblast layer of emerging teeth. At postnatal day P10, it is localized to the growth plate of several long bones, such as the forefoot digits, the hindfoot tarsals and the humerus, and expression is more intense in the chondrocytes of the hypertrophic zone.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000031684, Expressed in utricle of membranous labyrinth and 226 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5PT53, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5PT53, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000034111

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5PT53, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4821, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011932

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_039013_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5PT53

Identification of Orthologs from Complete Genome Data

More...
OMAi
FFFYGLK

Database of Orthologous Groups

More...
OrthoDBi
949808at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5PT53

TreeFam database of animal gene trees

More...
TreeFami
TF329411

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1530.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038770, Na+/solute_symporter_sf
IPR016833, Put_Na-Bile_cotransptr

The PANTHER Classification System

More...
PANTHERi
PTHR18640, PTHR18640, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13593, SBF_like, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF026166, UCP026166, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5PT53-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRLLERARKE WFMVGIVVAI GAAKLEPSVG VNGGPLKPEI TVSYIAVATI
60 70 80 90 100
FFNSGLSLKT EELTSALVHL RLHLFIQIFT LAFFPAAIWL FLQLLSVTSI
110 120 130 140 150
NEWLLKGLQT VGCMPPPVSS AVILTKAVGG NEAAAIFNSA FGSFLGIVVT
160 170 180 190 200
PVLLLLFLGS SSSVPFTSIF SQLFMTVVVP LVIGQIVRRY IKDWLERKKP
210 220 230 240 250
PFGVVSSSVL LMIIYTTFCD TFSNPNIDLD KFSLILILFI IVSVQLSFML
260 270 280 290 300
LTFIFSTRNN SGFTPADTVA IIFCSTHKSL TLGIPMLKIV FAGHEHLSLI
310 320 330 340
SVPLLIYHPA QILLGSVLVP TIKSWMVSRQ KGVKLTRPTV
Length:340
Mass (Da):37,256
Last modified:January 4, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE373F9E2F4848A5C
GO
Isoform 2 (identifier: Q5PT53-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     241-283: IVSVQLSFMLLTFIFSTRNNSGFTPADTVAIIFCSTHKSLTLG → R

Show »
Length:298
Mass (Da):32,750
Checksum:i4C1F9F22563BE1F6
GO
Isoform 3 (identifier: Q5PT53-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     158-185: Missing.

Show »
Length:312
Mass (Da):34,332
Checksum:i5CB5CE6967BD547F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1B0GR66A0A1B0GR66_MOUSE
Sodium/bile acid cotransporter 7
Slc10a7
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5PT52Q5PT52_MOUSE
Sodium/bile acid cotransporter 7
Slc10a7 P7
103Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC30613 differs from that shown. Reason: Erroneous termination. Truncated C-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti144F → V in BAB27214 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_023225158 – 185Missing in isoform 3. 1 PublicationAdd BLAST28
Alternative sequenceiVSP_023226241 – 283IVSVQ…SLTLG → R in isoform 2. 1 PublicationAdd BLAST43

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY825926 mRNA Translation: AAV80709.1
AY825928 mRNA Translation: AAV80711.1
AK010834 mRNA Translation: BAB27214.1
AK040517 mRNA Translation: BAC30613.1 Sequence problems.
AK079901 mRNA Translation: BAC37779.1
AK152752 mRNA Translation: BAE31467.1
AK152849 mRNA Translation: BAE31542.1
BC116666 mRNA Translation: AAI16667.1
BC116717 mRNA Translation: AAI16718.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40395.1 [Q5PT53-1]
CCDS85567.1 [Q5PT53-2]
CCDS85568.1 [Q5PT53-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001009981.1, NM_001009981.2 [Q5PT53-3]
NP_001269037.1, NM_001282108.1 [Q5PT53-2]
NP_084012.1, NM_029736.2 [Q5PT53-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000034111; ENSMUSP00000034111; ENSMUSG00000031684 [Q5PT53-1]
ENSMUST00000209490; ENSMUSP00000148199; ENSMUSG00000031684 [Q5PT53-2]
ENSMUST00000209992; ENSMUSP00000147659; ENSMUSG00000031684 [Q5PT53-3]
ENSMUST00000211286; ENSMUSP00000147724; ENSMUSG00000031684 [Q5PT53-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
76775

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:76775

UCSC genome browser

More...
UCSCi
uc009mid.2, mouse [Q5PT53-1]
uc012ggi.2, mouse [Q5PT53-3]
uc012ggk.2, mouse [Q5PT53-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY825926 mRNA Translation: AAV80709.1
AY825928 mRNA Translation: AAV80711.1
AK010834 mRNA Translation: BAB27214.1
AK040517 mRNA Translation: BAC30613.1 Sequence problems.
AK079901 mRNA Translation: BAC37779.1
AK152752 mRNA Translation: BAE31467.1
AK152849 mRNA Translation: BAE31542.1
BC116666 mRNA Translation: AAI16667.1
BC116717 mRNA Translation: AAI16718.1
CCDSiCCDS40395.1 [Q5PT53-1]
CCDS85567.1 [Q5PT53-2]
CCDS85568.1 [Q5PT53-3]
RefSeqiNP_001009981.1, NM_001009981.2 [Q5PT53-3]
NP_001269037.1, NM_001282108.1 [Q5PT53-2]
NP_084012.1, NM_029736.2 [Q5PT53-1]

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034111

PTM databases

PhosphoSitePlusiQ5PT53

Proteomic databases

PaxDbiQ5PT53
PRIDEiQ5PT53

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
27520, 91 antibodies

Genome annotation databases

EnsembliENSMUST00000034111; ENSMUSP00000034111; ENSMUSG00000031684 [Q5PT53-1]
ENSMUST00000209490; ENSMUSP00000148199; ENSMUSG00000031684 [Q5PT53-2]
ENSMUST00000209992; ENSMUSP00000147659; ENSMUSG00000031684 [Q5PT53-3]
ENSMUST00000211286; ENSMUSP00000147724; ENSMUSG00000031684 [Q5PT53-1]
GeneIDi76775
KEGGimmu:76775
UCSCiuc009mid.2, mouse [Q5PT53-1]
uc012ggi.2, mouse [Q5PT53-3]
uc012ggk.2, mouse [Q5PT53-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84068
MGIiMGI:1924025, Slc10a7

Phylogenomic databases

eggNOGiKOG4821, Eukaryota
GeneTreeiENSGT00390000011932
HOGENOMiCLU_039013_0_0_1
InParanoidiQ5PT53
OMAiFFFYGLK
OrthoDBi949808at2759
PhylomeDBiQ5PT53
TreeFamiTF329411

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
76775, 1 hit in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Slc10a7, mouse

Protein Ontology

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PROi
PR:Q5PT53
RNActiQ5PT53, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000031684, Expressed in utricle of membranous labyrinth and 226 other tissues
ExpressionAtlasiQ5PT53, baseline and differential
GenevisibleiQ5PT53, MM

Family and domain databases

Gene3Di1.20.1530.20, 1 hit
InterProiView protein in InterPro
IPR038770, Na+/solute_symporter_sf
IPR016833, Put_Na-Bile_cotransptr
PANTHERiPTHR18640, PTHR18640, 1 hit
PfamiView protein in Pfam
PF13593, SBF_like, 1 hit
PIRSFiPIRSF026166, UCP026166, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNTCP7_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5PT53
Secondary accession number(s): Q5PT51
, Q8BV58, Q8BYD0, Q9CWD6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: January 4, 2005
Last modified: December 2, 2020
This is version 111 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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