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Entry version 110 (02 Dec 2020)
Sequence version 2 (27 Jul 2011)
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Protein

HEAT repeat-containing protein 5A

Gene

Heatr5a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
HEAT repeat-containing protein 5A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Heatr5a
Synonyms:Kiaa1316
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444133, Heatr5a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003119911 – 2038HEAT repeat-containing protein 5AAdd BLAST2038

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1647PhosphoserineBy similarity1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5PRF0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5PRF0

PeptideAtlas

More...
PeptideAtlasi
Q5PRF0

PRoteomics IDEntifications database

More...
PRIDEi
Q5PRF0

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5PRF0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5PRF0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000035181, Expressed in blastocyst and 249 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5PRF0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5PRF0, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000043115

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5PRF0, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati850 – 887HEAT 1Add BLAST38
Repeati1082 – 1119HEAT 2Add BLAST38

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the HEATR5 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1822, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000006205

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000652_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5PRF0

Identification of Orthologs from Complete Genome Data

More...
OMAi
TERFHLI

Database of Orthologous Groups

More...
OrthoDBi
71064at2759

TreeFam database of animal gene trees

More...
TreeFami
TF300706

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024, ARM-type_fold
IPR040108, Laa1/Sip1/HEATR5

The PANTHER Classification System

More...
PANTHERi
PTHR21663, PTHR21663, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5PRF0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MELAHSLLLN EEASNQLGAV QKAEFIFEWL RYLEKLLLAT NREDVREKQK
60 70 80 90 100
TLVGQLLSLL NSSPGPPTRK LLAQDLAILY SVGDTVSVYE TIDKCNDLIR
110 120 130 140 150
SKDDSPSYLP TKLAAVVCLG SLYKKLGRIL ANGFTDTVVN ILKAMKSAES
160 170 180 190 200
QGRYEIMLSL QSILTGLGAA AAPCHRDVYK AARSCLTDRS MAVRCAAAKC
210 220 230 240 250
LLELQNEAIF MWSTDVDSVA TLCFKSFEGS NYDVRISVSK LLGTVLAKAV
260 270 280 290 300
TAKHPGAGSK QSARRVSLEE VLELLGAGFL RGSSGFLRAS GDMLKGNSSV
310 320 330 340 350
SRDVRVGVTQ AYVVFVSTLG GAWLEKNLAA FLSHILSLVS QSNPKATQTQ
360 370 380 390 400
IDAVCCRRCV SFILRATLGG LLGEKAQIAA AKEICQAVWR LKKVMDAALS
410 420 430 440 450
DGNVETRLSS TDVAASQHVL VCALQELGNL IHNLGTTAAP LLQDSSTGLL
460 470 480 490 500
DSVISVVLHP SISVRLAAAW CLHCIAVALP SYLTPLLDRC LERLAILKSS
510 520 530 540 550
PEAVTGFSSA VAALLGSVTH CPLGIPHGKG KIIMTIAEDL LCSAAQNSRL
560 570 580 590 600
SLQRTQAGWL LVAALMTLGP AVVSHHLTRV LLLWKCVFPA SPRDLETEKS
610 620 630 640 650
RGDSFTWQVT LEGRAGALCA VKSFISHCGD LLTEEVIQRL LPPLPCAVDL
660 670 680 690 700
LTQLSSILKT YGSSLKTPSI VYRQRLYELL ILLPPETYKG NLCVILKELA
710 720 730 740 750
AELTAPDTQA AASTCLLPAL CHPDDLLILS PLLQETDHRF IEEQLLLGNG
760 770 780 790 800
VACGSLEYDP YSIYEKDVEG DSVPKPLPPA LSVISSASKL FGVVCATVDE
810 820 830 840 850
AQRVLILEQL LNSIKHTKGA RQQTVQLHVV SAISNLLKYV AGSKQSLGPE
860 870 880 890 900
VRRLVLTLVL GALESPTPLL RCAASEAWAR LAQVADDGAF TAGLAQLSFD
910 920 930 940 950
KLKSARDVVT RTGHSLALGS LHRYLGGIGP QHLSSCIGVL YTLSQDSTSP
960 970 980 990 1000
DVQTWALHSL SLTIDSAGAL YHVHVESTLS LIVMLLLNVP PTHAQVHQSL
1010 1020 1030 1040 1050
GRCLNALITT LGPELQGSNT SVSALRTSCL LGCAVMQDHP GCLVQAQAIS
1060 1070 1080 1090 1100
CLQQLHMFAP RHVNLSSLVS CLCVNLCSPY LLLRRAVLAC LRQLVQREAA
1110 1120 1130 1140 1150
EVSEHAIMLA RDGRDAAADA NLREVGLEGA LLALLDRETD ESLCQDIRET
1160 1170 1180 1190 1200
LHHMLTSMAV GKLTLWLKLC KDVLAASADF TAVTCVDTMQ EEEGDRGDDA
1210 1220 1230 1240 1250
SVLTRGDDKP HPFSNPRWAT RVFAADCVCR IINQCENANR AHFDIALAQE
1260 1270 1280 1290 1300
MKKRDSRNDF LVLHLADLIR MAFMAATDHS DQLRLSGLDT LLVVIRRFAD
1310 1320 1330 1340 1350
IAEPEFPGHV ILEQYQANVG AALRPAFTSE TPPDITAKAC QVCSAWIASG
1360 1370 1380 1390 1400
VVSDLSDLRR VHQLLVSSLT KIQAGKEALS QLYNESASTM EILAVLRAWA
1410 1420 1430 1440 1450
EVYIIAVQRH KNHKQALKTT VNSEDSMRNG SSSAAGLLDL VCTDLATLSK
1460 1470 1480 1490 1500
LWLAALQDFA LLTLPAEFAS QLPTEGGAFY TAETSKSAKL HYHDSWALIL
1510 1520 1530 1540 1550
HAAALWLTST GFADPDEGGA NLSRPVTPTS MCQGSSSSGA AVKSPEDVYT
1560 1570 1580 1590 1600
DRFHLILGIS VEFLCSLRSD ASLESIMACL RALQALLDVP WPRWRIGSDQ
1610 1620 1630 1640 1650
DLGIELLNVL HRVILTRESP AIQLASLEVV RQIICAAQEH VKEKRRSAEV
1660 1670 1680 1690 1700
DDGASEKETL PEFGEGKDTG GLVPGKSLVF ATLELCVCIL VRQLPELNPK
1710 1720 1730 1740 1750
LAGSPGGKAS KPKTLLEEGS RLVAAALAIL AELPAVCSPE GSISILPTVL
1760 1770 1780 1790 1800
YLTIGVLRET AVKLPGGQLS CTVTASLQTL KGILTSPMAR AEKSHEAWTS
1810 1820 1830 1840 1850
LLQSALATVL DCWSPVDGAQ EPDEVSLLTA VTVFILSTSP EVTTVPCLQN
1860 1870 1880 1890 1900
RCIEKFKAAL ESKDSVVQMK TCQLLHSIFQ YPKPAVSYPY IYSLASSIVE
1910 1920 1930 1940 1950
KLQDIARRKP EDATELQLCQ EGIKLLEALV AIAEEEHRAQ LVACLLPILI
1960 1970 1980 1990 2000
SFLLDENALG SATSVTRSLH DFALHSLMQI GPRYSSVFKR VMASSPALKA
2010 2020 2030
RLEAAVKGNQ ESVRVDPPSK HAKNLARNSS IQLKTNFL
Length:2,038
Mass (Da):219,893
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i826E013A2C8002D5
GO
Isoform 2 (identifier: Q5PRF0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     654-2038: Missing.

Show »
Length:653
Mass (Da):70,088
Checksum:i9FCFBB712D27E9C2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1W2P7I6A0A1W2P7I6_MOUSE
HEAT repeat-containing protein 5A
Heatr5a
260Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC32998 differs from that shown. Reason: Frameshift.Curated
The sequence BAE43352 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti57L → V in BAC32998 (PubMed:16141072).Curated1
Sequence conflicti686E → G in BAE43352 (PubMed:16141072).Curated1
Sequence conflicti737D → N in BAE43352 (PubMed:16141072).Curated1
Sequence conflicti1070S → G in BAE43352 (PubMed:16141072).Curated1
Sequence conflicti1643E → G in AAH86656 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_029687654 – 2038Missing in isoform 2. 1 PublicationAdd BLAST1385

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK047221 mRNA Translation: BAC32998.1 Frameshift.
AK053055 mRNA Translation: BAE43352.1 Frameshift.
AK161523 mRNA Translation: BAE36441.1
AC157213 Genomic DNA No translation available.
AC161114 Genomic DNA No translation available.
BC063265 mRNA Translation: AAH63265.1
BC086656 mRNA Translation: AAH86656.1
AK122493 mRNA Translation: BAC65775.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS25902.1 [Q5PRF0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_796145.2, NM_177171.4 [Q5PRF0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000040583; ENSMUSP00000043115; ENSMUSG00000035181 [Q5PRF0-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
320487

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:320487

UCSC genome browser

More...
UCSCi
uc007nna.1, mouse [Q5PRF0-1]
uc007nnc.1, mouse [Q5PRF0-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK047221 mRNA Translation: BAC32998.1 Frameshift.
AK053055 mRNA Translation: BAE43352.1 Frameshift.
AK161523 mRNA Translation: BAE36441.1
AC157213 Genomic DNA No translation available.
AC161114 Genomic DNA No translation available.
BC063265 mRNA Translation: AAH63265.1
BC086656 mRNA Translation: AAH86656.1
AK122493 mRNA Translation: BAC65775.1
CCDSiCCDS25902.1 [Q5PRF0-1]
RefSeqiNP_796145.2, NM_177171.4 [Q5PRF0-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000043115

PTM databases

iPTMnetiQ5PRF0
PhosphoSitePlusiQ5PRF0

Proteomic databases

EPDiQ5PRF0
PaxDbiQ5PRF0
PeptideAtlasiQ5PRF0
PRIDEiQ5PRF0

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
63890, 10 antibodies

Genome annotation databases

EnsembliENSMUST00000040583; ENSMUSP00000043115; ENSMUSG00000035181 [Q5PRF0-1]
GeneIDi320487
KEGGimmu:320487
UCSCiuc007nna.1, mouse [Q5PRF0-1]
uc007nnc.1, mouse [Q5PRF0-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
25938
MGIiMGI:2444133, Heatr5a

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiKOG1822, Eukaryota
GeneTreeiENSGT00390000006205
HOGENOMiCLU_000652_0_0_1
InParanoidiQ5PRF0
OMAiTERFHLI
OrthoDBi71064at2759
TreeFamiTF300706

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
320487, 0 hits in 17 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Heatr5a, mouse

Protein Ontology

More...
PROi
PR:Q5PRF0
RNActiQ5PRF0, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000035181, Expressed in blastocyst and 249 other tissues
ExpressionAtlasiQ5PRF0, baseline and differential
GenevisibleiQ5PRF0, MM

Family and domain databases

InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR040108, Laa1/Sip1/HEATR5
PANTHERiPTHR21663, PTHR21663, 1 hit
SUPFAMiSSF48371, SSF48371, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHTR5A_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5PRF0
Secondary accession number(s): E9QPI0
, Q3TT84, Q3V311, Q6P4S9, Q80TF2, Q8C8F7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: July 27, 2011
Last modified: December 2, 2020
This is version 110 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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