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UniProtKB - Q5PQT4 (Q5PQT4_RAT)
Protein
Submitted name:
RCG45758, isoform CRA_b
Gene
Zbtb43
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- RNA polymerase III general transcription initiation factor binding Source: RGD
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific double-stranded DNA binding Source: RGD
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: RCG45758, isoform CRA_bImportedSubmitted name: Zinc finger and BTB domain-containing 43Imported |
Gene namesi | Name:Zbtb43Imported ORF Names:rCG_45758Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1310287, Zbtb43 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000017017, Expressed in liver and 20 other tissues |
Interactioni
GO - Molecular functioni
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000022814 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 69 – 133 | BTBInterPro annotationAdd BLAST | 65 | |
Domaini | 409 – 435 | C2H2-typeInterPro annotationAdd BLAST | 27 | |
Domaini | 436 – 463 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 464 – 493 | C2H2-typeInterPro annotationAdd BLAST | 30 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 170 – 263 | DisorderedSequence analysisAdd BLAST | 94 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 170 – 189 | Polar residuesSequence analysisAdd BLAST | 20 | |
Compositional biasi | 202 – 225 | Basic and acidic residuesSequence analysisAdd BLAST | 24 | |
Compositional biasi | 226 – 263 | Polar residuesSequence analysisAdd BLAST | 38 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000160616 |
HOGENOMi | CLU_029118_2_0_1 |
OMAi | IEMVAGI |
OrthoDBi | 830409at2759 |
TreeFami | TF333162 |
Family and domain databases
Gene3Di | 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF00096, zf-C2H2, 1 hit |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 1 hit PS50157, ZINC_FINGER_C2H2_2, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q5PQT4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPTNVYSSQI GHQGQSKVRF HQSPTCRTTL NKIGDEMEPG TNSFQVEFPD
60 70 80 90 100
FSSTILQKLN QQRQQGQLCD VSIVVQGHIF QAHKAVLAAS SPYFCDQVLL
110 120 130 140 150
KNSRRIVLPD VMNPRVFENI LLFSYTGRLV MPAPEIVSYL TAASFLQMWH
160 170 180 190 200
VVDKCTEVLE GNPTVLCQKL NHGSDHQSPS SSNYNGLAES FELGSGGHTD
210 220 230 240 250
FPKAQELRDG ENEEESTKDE LSSQVTEHEY LPSNSSTEHD RLSTEMASQD
260 270 280 290 300
GEEGTNDSTE FHYTRPLYSK PSIMPHRRWI HVKPERLEQP WDGMDVHAAY
310 320 330 340 350
DEHQVSESVN TMQTDHSAQP SGAEEEFQIV EKKVEVEFDE HAEGSNYDEQ
360 370 380 390 400
VDFYGSSMEE FSGEKLGGGL IGHKQETALA AGYSENIEMV MGIKEEASHL
410 420 430 440 450
GFSATDKLYP CQCGKSFTHK SQRDRHMSMH LGLRPYGCSV CGKKFKMKHH
460 470 480 490 500
LVGHMKIHTG IKPYECNICA KRFMWRDSFH RHVTSCTKSY EAAKAGQNTT
EAN
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A8I6AFN4 | A0A8I6AFN4_RAT | RCG45758, isoform CRA_a | Zbtb43 rCG_45758 | 467 | Annotation score: | ||
A0A8I5ZT40 | A0A8I5ZT40_RAT | Zinc finger and BTB domain-containi... | Zbtb43 | 577 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC087042 mRNA Translation: AAH87042.1 CH474001 Genomic DNA Translation: EDL93189.1 |
RefSeqi | NP_001012094.1, NM_001012094.1 |
Genome annotation databases
Ensembli | ENSRNOT00000095180.1; ENSRNOP00000095240.1; ENSRNOG00000017017.6 |
GeneIDi | 311872 |
KEGGi | rno:311872 |
UCSCi | RGD:1310287, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC087042 mRNA Translation: AAH87042.1 CH474001 Genomic DNA Translation: EDL93189.1 |
RefSeqi | NP_001012094.1, NM_001012094.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000022814 |
Genome annotation databases
Ensembli | ENSRNOT00000095180.1; ENSRNOP00000095240.1; ENSRNOG00000017017.6 |
GeneIDi | 311872 |
KEGGi | rno:311872 |
UCSCi | RGD:1310287, rat |
Organism-specific databases
CTDi | 23099 |
RGDi | 1310287, Zbtb43 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000160616 |
HOGENOMi | CLU_029118_2_0_1 |
OMAi | IEMVAGI |
OrthoDBi | 830409at2759 |
TreeFami | TF333162 |
Gene expression databases
Bgeei | ENSRNOG00000017017, Expressed in liver and 20 other tissues |
Family and domain databases
Gene3Di | 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF00096, zf-C2H2, 1 hit |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 1 hit PS50157, ZINC_FINGER_C2H2_2, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5PQT4_RAT | |
Accessioni | Q5PQT4Primary (citable) accession number: Q5PQT4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 4, 2005 |
Last sequence update: | January 4, 2005 | |
Last modified: | May 25, 2022 | |
This is version 140 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |