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Protein

Protein phosphatase 1 regulatory subunit 42

Gene

ppp1r42

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May regulate phosphatase activity of protein phosphatase 1 (PP1) complexes.By similarity

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase 1 regulatory subunit 42
Alternative name(s):
Leucine-rich repeat-containing protein 67
Gene namesi
Name:ppp1r42
Synonyms:lrrc67
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-6252819 ppp1r42

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003261791 – 372Protein phosphatase 1 regulatory subunit 42Add BLAST372

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ5PPX0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati30 – 51LRR 1Add BLAST22
Repeati52 – 71LRR 2Add BLAST20
Repeati72 – 93LRR 3Add BLAST22
Repeati94 – 115LRR 4Add BLAST22
Repeati116 – 137LRR 5Add BLAST22
Repeati146 – 167LRR 6Add BLAST22
Repeati168 – 189LRR 7Add BLAST22
Domaini203 – 241LRRCTAdd BLAST39

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi248 – 251Poly-Lys4

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

HOVERGENiHBG061602
KOiK17579

Family and domain databases

Gene3Di3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR001611 Leu-rich_rpt
IPR025875 Leu-rich_rpt_4
IPR032675 LRR_dom_sf
PfamiView protein in Pfam
PF12799 LRR_4, 1 hit
PROSITEiView protein in PROSITE
PS51450 LRR, 6 hits

Sequencei

Sequence statusi: Complete.

Q5PPX0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRLTVDLVM KNSNVLRNRK DESLARHLRR ITHLNFSNKN IDEVEDLTMC
60 70 80 90 100
RNLTVLYLYD NNINQIKNLG SNLTHLYLQN NCISCIENLS GLKRLEKLYL
110 120 130 140 150
GGNCLTVVEG LEGLRELREL HIENQRLPPG EKLLFDPRTL HFLGISLSVL
160 170 180 190 200
NISNNNIDEL KDLAVLENLT QFVAADNQLK EIKDLEFVLS KWTKLCRMDL
210 220 230 240 250
SGNPVCLKPK YREKVTIISK TLEILDGKEI KEMARQFLLN WKASRISKKK
260 270 280 290 300
KNLENMTGPS LLPQLYESDN YRSLLPVYNQ NFRHQLLEQP KYIVMAHTQS
310 320 330 340 350
CNKHGQLQRS AGKRNISVIE DIKSEARGME SFSGCIPESE CVGGQHGNER
360 370
PGYPTNLINL WKGEKDETEG IP
Length:372
Mass (Da):42,698
Last modified:January 4, 2005 - v1
Checksum:i1F9F037260A16103
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087459 mRNA Translation: AAH87459.1
RefSeqiNP_001088790.1, NM_001095321.1
UniGeneiXl.50128

Genome annotation databases

GeneIDi496055
KEGGixla:496055

Similar proteinsi

Entry informationi

Entry nameiPPR42_XENLA
AccessioniPrimary (citable) accession number: Q5PPX0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: January 4, 2005
Last modified: February 28, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

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