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Protein
Submitted name:

Hairy and enhancer of split 6 (Drosophila)

Gene

Hes6

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Hairy and enhancer of split 6 (Drosophila)Imported
Submitted name:
Hes family bHLH transcription factor 6Imported
Gene namesi
Name:Hes6Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 9

Organism-specific databases

RGDi1312047 Hes6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000020194 Expressed in 10 organ(s), highest expression level in liver

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000063598

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 87BHLHInterPro annotationAdd BLAST53
Domaini106 – 139OrangeInterPro annotationAdd BLAST34

Phylogenomic databases

eggNOGiKOG4304 Eukaryota
ENOG4111F0X LUCA
GeneTreeiENSGT00700000104168
HOGENOMiHOG000236346
HOVERGENiHBG107098
KOiK09087
OMAiQSVWRPW
OrthoDBiEOG091G0OZ5
TreeFamiTF351373

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR003650 Orange_dom
PfamiView protein in Pfam
PF07527 Hairy_orange, 1 hit
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
PS51054 ORANGE, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5PPN0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRTVGKHGGT ARCGQGLRVD GPAGGCTGQG LSSRFPQARK PLVEKKRRAR
60 70 80 90 100
INESLQELRL LLAGTEVQAK LENAEVLELT VRRVQGALRG RAREREQLQA
110 120 130 140 150
EASERFAAGY IQCMHEVHTF VSTCQAIDAT VSAELLNHLL ESMPLREGSS
160 170 180 190 200
FRDLLGDSLA GLPGGSGRSS WPPGGSPESP LSSPPGPGDD LCSDLEEIPE
210 220 230
AELNRVPAEG PDLVPTSLGI LTTARRAQSV WRPW
Length:234
Mass (Da):25,134
Last modified:January 4, 2005 - v1
Checksum:iBFB379567C9AB8FE
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2K6W4A0A0G2K6W4_RAT
Hairy and enhancer of split 6 (Dros...
Hes6 rCG_55552
224Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07073506 Genomic DNA No translation available.
BC087597 mRNA Translation: AAH87597.1
RefSeqiNP_001013197.1, NM_001013179.1
UniGeneiRn.11980

Genome annotation databases

EnsembliENSRNOT00000066346; ENSRNOP00000063598; ENSRNOG00000020194
GeneIDi316626
KEGGirno:316626
UCSCiRGD:1312047 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07073506 Genomic DNA No translation available.
BC087597 mRNA Translation: AAH87597.1
RefSeqiNP_001013197.1, NM_001013179.1
UniGeneiRn.11980

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000063598

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000066346; ENSRNOP00000063598; ENSRNOG00000020194
GeneIDi316626
KEGGirno:316626
UCSCiRGD:1312047 rat

Organism-specific databases

CTDi55502
RGDi1312047 Hes6

Phylogenomic databases

eggNOGiKOG4304 Eukaryota
ENOG4111F0X LUCA
GeneTreeiENSGT00700000104168
HOGENOMiHOG000236346
HOVERGENiHBG107098
KOiK09087
OMAiQSVWRPW
OrthoDBiEOG091G0OZ5
TreeFamiTF351373

Gene expression databases

BgeeiENSRNOG00000020194 Expressed in 10 organ(s), highest expression level in liver

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR003650 Orange_dom
PfamiView protein in Pfam
PF07527 Hairy_orange, 1 hit
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
PS51054 ORANGE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5PPN0_RAT
AccessioniPrimary (citable) accession number: Q5PPN0
Entry historyiIntegrated into UniProtKB/TrEMBL: January 4, 2005
Last sequence update: January 4, 2005
Last modified: November 7, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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