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UniProtKB - Q5PPH4 (ZN414_RAT)
Protein
Zinc finger protein 414
Gene
Znf414
Organism
Rattus norvegicus (Rat)
Status
Functioni
May be involved in transcriptional regulation.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 99 – 123 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 25 | |
Zinc fingeri | 135 – 159 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 25 | |
Zinc fingeri | 166 – 190 | C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST | 25 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Zinc finger protein 414 |
Gene namesi | Name:Znf414 Synonyms:Zfp414 |
Organismi | Rattus norvegicus (Rat) |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1308123, Zfp414 |
Subcellular locationi
Nucleus
- Nucleus Curated
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000242165 | 1 – 299 | Zinc finger protein 414Add BLAST | 299 |
Proteomic databases
PaxDbi | Q5PPH4 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000008378, Expressed in testis and 21 other tissues |
Genevisiblei | Q5PPH4, RN |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 102 | DisorderedSequence analysisAdd BLAST | 102 | |
Regioni | 193 – 228 | DisorderedSequence analysisAdd BLAST | 36 | |
Regioni | 254 – 299 | DisorderedSequence analysisAdd BLAST | 46 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 7 – 24 | Polar residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 66 – 82 | Polar residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 193 – 207 | Pro residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 264 – 289 | Polar residuesSequence analysisAdd BLAST | 26 |
Sequence similaritiesi
Belongs to the krueppel C2H2-type zinc-finger protein family.Curated
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 99 – 123 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 25 | |
Zinc fingeri | 135 – 159 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 25 | |
Zinc fingeri | 166 – 190 | C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST | 25 |
Keywords - Domaini
Repeat, Zinc-fingerPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00390000006876 |
HOGENOMi | CLU_049178_0_0_1 |
InParanoidi | Q5PPH4 |
OMAi | AHLHTCS |
OrthoDBi | 943003at2759 |
PhylomeDBi | Q5PPH4 |
TreeFami | TF337512 |
Family and domain databases
InterProi | View protein in InterPro IPR039882, ZN414 IPR031799, Znf-C2H2_ribbon IPR013087, Znf_C2H2_type |
PANTHERi | PTHR21695, PTHR21695, 1 hit |
Pfami | View protein in Pfam PF15909, zf-C2H2_8, 1 hit |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 3 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 2 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
i Sequence
Sequence statusi: Complete.
Q5PPH4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEELSGPSSD TLATVESSSN EPDKEVASPD VAATATLSSV EEPGPNPTAT
60 70 80 90 100
PPVWDRGGPL QQVACPVPDS CQTSSTTRGV GTNEDLRLPR RRPPPGKQIP
110 120 130 140 150
CSSPGCSLSF PSVRDLAQHL RTHCPPTQSL EGKLFRCSAL SCTESFPSMQ
160 170 180 190 200
ELVAHGKLHY KPNRYFKCEN CLLRFRTHRS LFKHLHVCID HGQNPAPPPP
210 220 230 240 250
PALDKEPPVP ERPPESDPSS SLGLPFPLLE PFTSAPTGPF LPYLNPAPFG
260 270 280 290
LSPPRLRPFL AATPGPPTSS TAIWKKSQGA TSSPRRPQGG SDAPSGACR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC087693 mRNA Translation: AAH87693.1 |
RefSeqi | NP_001009664.1, NM_001009664.1 |
Genome annotation databases
Ensembli | ENSRNOT00000011094; ENSRNOP00000011094; ENSRNOG00000008378 |
GeneIDi | 299647 |
KEGGi | rno:299647 |
UCSCi | RGD:1308123, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC087693 mRNA Translation: AAH87693.1 |
RefSeqi | NP_001009664.1, NM_001009664.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000011094 |
Proteomic databases
PaxDbi | Q5PPH4 |
Genome annotation databases
Ensembli | ENSRNOT00000011094; ENSRNOP00000011094; ENSRNOG00000008378 |
GeneIDi | 299647 |
KEGGi | rno:299647 |
UCSCi | RGD:1308123, rat |
Organism-specific databases
CTDi | 328801 |
RGDi | 1308123, Zfp414 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00390000006876 |
HOGENOMi | CLU_049178_0_0_1 |
InParanoidi | Q5PPH4 |
OMAi | AHLHTCS |
OrthoDBi | 943003at2759 |
PhylomeDBi | Q5PPH4 |
TreeFami | TF337512 |
Miscellaneous databases
PROi | PR:Q5PPH4 |
Gene expression databases
Bgeei | ENSRNOG00000008378, Expressed in testis and 21 other tissues |
Genevisiblei | Q5PPH4, RN |
Family and domain databases
InterProi | View protein in InterPro IPR039882, ZN414 IPR031799, Znf-C2H2_ribbon IPR013087, Znf_C2H2_type |
PANTHERi | PTHR21695, PTHR21695, 1 hit |
Pfami | View protein in Pfam PF15909, zf-C2H2_8, 1 hit |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 3 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 2 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | ZN414_RAT | |
Accessioni | Q5PPH4Primary (citable) accession number: Q5PPH4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 27, 2006 |
Last sequence update: | January 4, 2005 | |
Last modified: | February 23, 2022 | |
This is version 103 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families