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Protein

Zinc finger protein 414

Gene

Znf414

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri99 – 123C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri135 – 159C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri166 – 190C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST25

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 414
Gene namesi
Name:Znf414
Synonyms:Zfp414
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1308123 Zfp414

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002421651 – 299Zinc finger protein 414Add BLAST299

Proteomic databases

PaxDbiQ5PPH4
PRIDEiQ5PPH4

Expressioni

Gene expression databases

BgeeiENSRNOG00000008378 Expressed in 10 organ(s), highest expression level in testis
GenevisibleiQ5PPH4 RN

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011094

Structurei

3D structure databases

ProteinModelPortaliQ5PPH4
SMRiQ5PPH4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi195 – 267Pro-richAdd BLAST73

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri99 – 123C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri135 – 159C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri166 – 190C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST25

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00390000006876
HOGENOMiHOG000015387
HOVERGENiHBG083015
InParanoidiQ5PPH4
OMAiEGECPVF
OrthoDBiEOG091G0DB2
PhylomeDBiQ5PPH4
TreeFamiTF337512

Family and domain databases

InterProiView protein in InterPro
IPR039882 ZN414
IPR031799 Znf-C2H2_ribbon
IPR013087 Znf_C2H2_type
PANTHERiPTHR21695 PTHR21695, 1 hit
PfamiView protein in Pfam
PF15909 zf-C2H2_8, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 2 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequencei

Sequence statusi: Complete.

Q5PPH4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEELSGPSSD TLATVESSSN EPDKEVASPD VAATATLSSV EEPGPNPTAT
60 70 80 90 100
PPVWDRGGPL QQVACPVPDS CQTSSTTRGV GTNEDLRLPR RRPPPGKQIP
110 120 130 140 150
CSSPGCSLSF PSVRDLAQHL RTHCPPTQSL EGKLFRCSAL SCTESFPSMQ
160 170 180 190 200
ELVAHGKLHY KPNRYFKCEN CLLRFRTHRS LFKHLHVCID HGQNPAPPPP
210 220 230 240 250
PALDKEPPVP ERPPESDPSS SLGLPFPLLE PFTSAPTGPF LPYLNPAPFG
260 270 280 290
LSPPRLRPFL AATPGPPTSS TAIWKKSQGA TSSPRRPQGG SDAPSGACR
Length:299
Mass (Da):31,967
Last modified:January 4, 2005 - v1
Checksum:i0988FF9C3263345B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087693 mRNA Translation: AAH87693.1
RefSeqiNP_001009664.1, NM_001009664.1
UniGeneiRn.32868

Genome annotation databases

EnsembliENSRNOT00000011094; ENSRNOP00000011094; ENSRNOG00000008378
GeneIDi299647
KEGGirno:299647
UCSCiRGD:1308123 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087693 mRNA Translation: AAH87693.1
RefSeqiNP_001009664.1, NM_001009664.1
UniGeneiRn.32868

3D structure databases

ProteinModelPortaliQ5PPH4
SMRiQ5PPH4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011094

Proteomic databases

PaxDbiQ5PPH4
PRIDEiQ5PPH4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000011094; ENSRNOP00000011094; ENSRNOG00000008378
GeneIDi299647
KEGGirno:299647
UCSCiRGD:1308123 rat

Organism-specific databases

CTDi328801
RGDi1308123 Zfp414

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00390000006876
HOGENOMiHOG000015387
HOVERGENiHBG083015
InParanoidiQ5PPH4
OMAiEGECPVF
OrthoDBiEOG091G0DB2
PhylomeDBiQ5PPH4
TreeFamiTF337512

Miscellaneous databases

PROiPR:Q5PPH4

Gene expression databases

BgeeiENSRNOG00000008378 Expressed in 10 organ(s), highest expression level in testis
GenevisibleiQ5PPH4 RN

Family and domain databases

InterProiView protein in InterPro
IPR039882 ZN414
IPR031799 Znf-C2H2_ribbon
IPR013087 Znf_C2H2_type
PANTHERiPTHR21695 PTHR21695, 1 hit
PfamiView protein in Pfam
PF15909 zf-C2H2_8, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 2 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiZN414_RAT
AccessioniPrimary (citable) accession number: Q5PPH4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: January 4, 2005
Last modified: November 7, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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