Znf414

Functionⁱ

May be involved in transcriptional regulation.

Regions

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	99 – 123	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	135 – 159	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	166 – 190	C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST	25

GO - Molecular functionⁱ

DNA binding Source: UniProtKB-KW
metal ion binding Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-binding
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger protein 414
Gene namesⁱ	Name:Znf414 Synonyms:Zfp414
Organismⁱ	Rattus norvegicus (Rat)
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 7

Organism-specific databases

Rat genome database More...RGDⁱ	1308123 Zfp414

RGDⁱ

1308123 Zfp414

Keywords - Cellular componentⁱ

Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000242165	1 – 299	Zinc finger protein 414Add BLAST		299

Proteomic databases

PaxDbⁱ	Q5PPH4
PRIDEⁱ	Q5PPH4

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000008378 Expressed in 10 organ(s), highest expression level in testis
Genevisibleⁱ	Q5PPH4 RN

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000011094

STRINGⁱ

10116.ENSRNOP00000011094

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q5PPH4
SMRⁱ	Q5PPH4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	195 – 267	Pro-richAdd BLAST		73

Sequence similaritiesⁱ

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	99 – 123	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	135 – 159	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	166 – 190	C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST	25

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000006876
HOGENOMⁱ	HOG000015387
HOVERGENⁱ	HBG083015
InParanoidⁱ	Q5PPH4
OMAⁱ	EGECPVF
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0DB2
PhylomeDBⁱ	Q5PPH4
TreeFamⁱ	TF337512

Family and domain databases

InterProⁱ	View protein in InterPro IPR039882 ZN414 IPR031799 Znf-C2H2_ribbon IPR013087 Znf_C2H2_type
PANTHERⁱ	PTHR21695 PTHR21695, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF15909 zf-C2H2_8, 1 hit
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 3 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 2 hits PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

Q5PPH4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MEELSGPSSD TLATVESSSN EPDKEVASPD VAATATLSSV EEPGPNPTAT 
        60         70         80         90        100
PPVWDRGGPL QQVACPVPDS CQTSSTTRGV GTNEDLRLPR RRPPPGKQIP 
       110        120        130        140        150
CSSPGCSLSF PSVRDLAQHL RTHCPPTQSL EGKLFRCSAL SCTESFPSMQ 
       160        170        180        190        200
ELVAHGKLHY KPNRYFKCEN CLLRFRTHRS LFKHLHVCID HGQNPAPPPP 
       210        220        230        240        250
PALDKEPPVP ERPPESDPSS SLGLPFPLLE PFTSAPTGPF LPYLNPAPFG 
       260        270        280        290 
LSPPRLRPFL AATPGPPTSS TAIWKKSQGA TSSPRRPQGG SDAPSGACR

Length:299

Mass (Da):31,967

Last modified:January 4, 2005 - v1

Checksum:ⁱ0988FF9C3263345B

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC087693 mRNA Translation: AAH87693.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001009664.1, NM_001009664.1
UniGeneⁱ	Rn.32868

Genome annotation databases

Ensemblⁱ	ENSRNOT00000011094; ENSRNOP00000011094; ENSRNOG00000008378
GeneIDⁱ	299647
KEGGⁱ	rno:299647
UCSC genome browser More...UCSCⁱ	RGD:1308123 rat

Similar proteinsⁱ

50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q5PPH4	Uncharacterized protein		AOTNA		258	UniRef50_Q5PPH4
Uncharacterized protein		RHIRO		312
Uncharacterized protein (Fragment)		MACFA		318
Zinc finger protein 414 isoform 2		MACMU		312
Uncharacterized protein		COLAP		312
+63

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC087693 mRNA Translation: AAH87693.1
RefSeqⁱ	NP_001009664.1, NM_001009664.1
UniGeneⁱ	Rn.32868

3D structure databases

ProteinModelPortalⁱ	Q5PPH4
SMRⁱ	Q5PPH4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000011094

STRINGⁱ

10116.ENSRNOP00000011094

Proteomic databases

PaxDbⁱ	Q5PPH4
PRIDEⁱ	Q5PPH4

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000011094; ENSRNOP00000011094; ENSRNOG00000008378
GeneIDⁱ	299647
KEGGⁱ	rno:299647
UCSCⁱ	RGD:1308123 rat

Organism-specific databases

CTDⁱ	328801
RGDⁱ	1308123 Zfp414

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00390000006876
HOGENOMⁱ	HOG000015387
HOVERGENⁱ	HBG083015
InParanoidⁱ	Q5PPH4
OMAⁱ	EGECPVF
OrthoDBⁱ	EOG091G0DB2
PhylomeDBⁱ	Q5PPH4
TreeFamⁱ	TF337512

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q5PPH4

PROⁱ

PR:Q5PPH4

Gene expression databases

Bgeeⁱ	ENSRNOG00000008378 Expressed in 10 organ(s), highest expression level in testis
Genevisibleⁱ	Q5PPH4 RN

Family and domain databases

InterProⁱ	View protein in InterPro IPR039882 ZN414 IPR031799 Znf-C2H2_ribbon IPR013087 Znf_C2H2_type
PANTHERⁱ	PTHR21695 PTHR21695, 1 hit
Pfamⁱ	View protein in Pfam PF15909 zf-C2H2_8, 1 hit
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 3 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 2 hits PS50157 ZINC_FINGER_C2H2_2, 3 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ZN414_RAT
Accessionⁱ	Q5PPH4Primary (citable) accession number: Q5PPH4
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
	Last sequence update:	January 4, 2005
	Last modified:	November 7, 2018
	This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5PPH4 (ZN414_RAT)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Zinc finger protein 414

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ