UniProtKB - Q5NLV1 (Q5NLV1_ZYMMO)
Protein
D-3-phosphoglycerate dehydrogenase
Gene
ZMO1685
Organism
Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Status
Functioni
Catalytic activityi
- EC:1.1.1.95UniRule annotation
: L-serine biosynthesis Pathwayi
This protein is involved in step 1 of the subpathway that synthesizes L-serine from 3-phospho-D-glycerate.UniRule annotationProteins known to be involved in the 3 steps of the subpathway in this organism are:
- D-3-phosphoglycerate dehydrogenase (ZMO1685)
- no protein annotated in this organism
- no protein annotated in this organism
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-serine from 3-phospho-D-glycerate, the pathway L-serine biosynthesis and in Amino-acid biosynthesis.
GO - Molecular functioni
- NAD binding Source: UniProtKB-UniRule
- phosphoglycerate dehydrogenase activity Source: UniProtKB-EC
GO - Biological processi
- L-serine biosynthetic process Source: UniProtKB-KW
Keywordsi
Molecular function | OxidoreductaseUniRule annotationARBA annotation |
Biological process | Amino-acid biosynthesis, Serine biosynthesisUniRule annotation |
Ligand | NADUniRule annotation |
Enzyme and pathway databases
UniPathwayi | UPA00135;UER00196 |
Names & Taxonomyi
Protein namesi | Recommended name: D-3-phosphoglycerate dehydrogenaseUniRule annotation (EC:1.1.1.95UniRule annotation) |
Gene namesi | Ordered Locus Names:ZMO1685Imported |
Organismi | Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)Imported |
Taxonomic identifieri | 264203 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Zymomonas › |
Proteomesi |
|
Family & Domainsi
Sequence similaritiesi
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0111, Bacteria |
HOGENOMi | CLU_019796_8_1_5 |
OMAi | NIAGMQV |
OrthoDBi | 1638924at2 |
Family and domain databases
Gene3Di | 3.30.1330.90, 1 hit |
InterProi | View protein in InterPro IPR029009, ASB_dom_sf IPR006139, D-isomer_2_OHA_DH_cat_dom IPR029753, D-isomer_DH_CS IPR006140, D-isomer_DH_NAD-bd IPR036291, NAD(P)-bd_dom_sf IPR006236, PGDH |
Pfami | View protein in Pfam PF00389, 2-Hacid_dh, 1 hit PF02826, 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF143548, SSF143548, 1 hit SSF51735, SSF51735, 1 hit |
TIGRFAMsi | TIGR01327, PGDH, 1 hit |
PROSITEi | View protein in PROSITE PS00670, D_2_HYDROXYACID_DH_2, 1 hit PS00671, D_2_HYDROXYACID_DH_3, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5NLV1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTRVLISDKM DPRAAEVFRE RGVEVDQITG LSPEELKKII NDYDGLAIRS
60 70 80 90 100
ATKVTKDIIA EAKNLKVIGR AGIGVDNIDI PAASSAGIVV MNTPFGNSIT
110 120 130 140 150
TAEQAIALMF ALARQIPEAN ASTQASKWEK NRFMGVEVSG KTLGLIGAGN
160 170 180 190 200
IGSIVADRAV GLKMKVIAYD PFLTPERALE LGIEKADLET LLHKADFITL
210 220 230 240 250
HVPLTDQTRN ILSRENLAKT KKGVRIINCA RGGLIDEEAL KDALESGHVA
260 270 280 290 300
GAALDVFLKE PAKENPLFGV PNFIATPHLG ASTTEAQVNV AIQVAEQMAD
310 320 330 340 350
YLLTGGVSNA LNMPSLSAEE APRVRPYMAL SEQLGRLLGQ LEGDKIKSVS
360 370 380 390 400
IEVEGAAAHL DQKPITSAVL SGLMGVYSQS VNMVNAPFLA RERGLDVREI
410 420 430 440 450
RHDREGAYHT LIRVTSRDDK GQEKSVAGTL FGSEGTRLVE IFGIKIEANL
460 470 480 490 500
SGDMLYIVND DAPGFIGRLG TLLGKAGVNI GTFHLGRRNT GGEAVLLLSV
510 520
DSPVTAGKMA KVAELSGVRE VKSLHFL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE008692 Genomic DNA Translation: AAV90309.1 |
RefSeqi | WP_011241433.1, NZ_CP035711.1 |
Genome annotation databases
EnsemblBacteriai | AAV90309; AAV90309; ZMO1685 |
KEGGi | zmo:ZMO1685 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE008692 Genomic DNA Translation: AAV90309.1 |
RefSeqi | WP_011241433.1, NZ_CP035711.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 264203.ZMO1685 |
Genome annotation databases
EnsemblBacteriai | AAV90309; AAV90309; ZMO1685 |
KEGGi | zmo:ZMO1685 |
Phylogenomic databases
eggNOGi | COG0111, Bacteria |
HOGENOMi | CLU_019796_8_1_5 |
OMAi | NIAGMQV |
OrthoDBi | 1638924at2 |
Enzyme and pathway databases
UniPathwayi | UPA00135;UER00196 |
Family and domain databases
Gene3Di | 3.30.1330.90, 1 hit |
InterProi | View protein in InterPro IPR029009, ASB_dom_sf IPR006139, D-isomer_2_OHA_DH_cat_dom IPR029753, D-isomer_DH_CS IPR006140, D-isomer_DH_NAD-bd IPR036291, NAD(P)-bd_dom_sf IPR006236, PGDH |
Pfami | View protein in Pfam PF00389, 2-Hacid_dh, 1 hit PF02826, 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF143548, SSF143548, 1 hit SSF51735, SSF51735, 1 hit |
TIGRFAMsi | TIGR01327, PGDH, 1 hit |
PROSITEi | View protein in PROSITE PS00670, D_2_HYDROXYACID_DH_2, 1 hit PS00671, D_2_HYDROXYACID_DH_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5NLV1_ZYMMO | |
Accessioni | Q5NLV1Primary (citable) accession number: Q5NLV1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 1, 2005 |
Last sequence update: | February 1, 2005 | |
Last modified: | December 2, 2020 | |
This is version 110 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |