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Entry version 63 (08 May 2019)
Sequence version 1 (01 Feb 2005)
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Protein

Endoglucanase

Gene

cel

Organism
uncultured bacterium
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.UniRule annotation EC:3.2.1.4

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei512PROSITE-ProRule annotation1
Active sitei554PROSITE-ProRule annotation1
Active sitei563PROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidasePROSITE-ProRule annotation, Hydrolase
Biological processCarbohydrate metabolism, Cellulose degradationUniRule annotation, Polysaccharide degradation

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
CBM32 Carbohydrate-Binding Module Family 32
GH9 Glycoside Hydrolase Family 9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
EndoglucanaseUniRule annotation (EC:3.2.1.4UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:celImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>Organismiuncultured bacteriumImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri77133 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaenvironmental samples

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 26UniRule annotationAdd BLAST26
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500514371227 – 1118EndoglucanaseUniRule annotationAdd BLAST1092

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini655 – 796F5/8 type CInterPro annotationAdd BLAST142

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 9 (cellulase E) family.PROSITE-ProRule annotation

Keywords - Domaini

SignalUniRule annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd02850 E_set_Cellulase_N, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.50.10.10, 1 hit
2.60.120.260, 1 hit
2.60.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR004197 Cellulase_Ig-like
IPR000421 FA58C
IPR008979 Galactose-bd-like_sf
IPR001701 Glyco_hydro_9
IPR033126 Glyco_hydro_9_Asp/Glu_AS
IPR018221 Glyco_hydro_9_His_AS
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR026444 Secre_tail

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02927 CelD_N, 1 hit
PF00754 F5_F8_type_C, 1 hit
PF00759 Glyco_hydro_9, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48208 SSF48208, 1 hit
SSF49785 SSF49785, 1 hit
SSF81296 SSF81296, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR04183 Por_Secre_tail, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50022 FA58C_3, 1 hit
PS00592 GH9_2, 1 hit
PS00698 GH9_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5NJL8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRLLFQIASM LLAAILLSAA WTSAEAYRPF KVNQAGYHPD ADKLAVVPVN
60 70 80 90 100
GSVLTTSQYQ IVDVESGDTV FTGALLGGDG LYWEHSDETV LHALFTDLST
110 120 130 140 150
PGTYRIEHPD LGESHPFEIS EEVLTEVSRS ALKAYYFNRA STEITEPYAG
160 170 180 190 200
PWARPMGHPD DNAMIHSSAA TEHRPVGYTF SSSKGWYDAG DFNKYIVNSG
210 220 230 240 250
ITTYTLLAAY EHFPNYFEEL TVNIPESGSG VPDILDEIRW NLDWMITMQD
260 270 280 290 300
PHDGGVYHKL TSPQFSGIIM PHQDNSARYA VQKSTAATLN FAGVMAVASR
310 320 330 340 350
VYRPYDRDFS ERALAAAEFA WQWALEHPNL YYRQDAMNQE HSPDIVTGEY
360 370 380 390 400
GDSNVSDEFD WAAAELYITT GDDSYWHARN LGNVHGITIP AWPQVRPLAW
410 420 430 440 450
VSLAHHRDRL TPAANVGHIT GRIEQMANEL LNAHNNSAYL MSMGYRGGGD
460 470 480 490 500
FVWGSNSVAL NHSLMLLQGY RLTGNGSMLD AAQANLDYVL GRNPTGYSFV
510 520 530 540 550
TGIGSRTPMD PHHRPSAAHS HDAPVPGLVV GGPHSGQQDG CNYPSDLPAL
560 570 580 590 600
SYVDDWCSYA TNEVAINWNA PLVYVAGAID AIRQETEQRT RARLSAHPLL
610 620 630 640 650
IIENDSAELI WSATGAQTVT LNGEQVPQSG SRMVQPADTT EYVLIATGEG
660 670 680 690 700
GEADTARVTI NVVPPEKFNR ASTGTAQASS SRTGNAPENV IDGRADTYWI
710 720 730 740 750
ADSAGDAWIE VDLLKAFDIR RVVLGWADSG YASRYDVLVS FDGVRWTPLH
760 770 780 790 800
EVQDGGGGTD EHIDETPVSG RFVRVSAPQS VDGEPLRLSE LEVYGLESER
810 820 830 840 850
QPPAVTLLAP ADGQEAETGT VIRFIADITP GSSGQPEAWF LINGEPVADV
860 870 880 890 900
TSEPFEYEWI AGEPGLYTIS VQVTDDHFEI QSRASELTVV EVPETRWYEV
910 920 930 940 950
ASASLSGGAE LLPDDTARDG VFVRTGDSGS LLWDRILAGE RRAYDIRVGY
960 970 980 990 1000
RLPGNTTATL RVRYPPRLEL REQLSGTQGE WHYRDFSGVM LNRGENSILL
1010 1020 1030 1040 1050
QAQDGSIDIA YLAVRGEGQE VTSAGDEAGV PEVYSLEQNY PNPFNPVTVI
1060 1070 1080 1090 1100
GFDLPVQEHV QLVVYDMLGR RVSVLMDDVM PAGSHKIPFD ASRLASGVYL
1110
YRITSGNFVQ SRQMMLVK
Length:1,118
Mass (Da):122,678
Last modified:February 1, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i48A97F1713B26DF0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ622824 Genomic DNA Translation: CAF22221.1

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ622824 Genomic DNA Translation: CAF22221.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

CAZyiCBM32 Carbohydrate-Binding Module Family 32
GH9 Glycoside Hydrolase Family 9

Family and domain databases

CDDicd02850 E_set_Cellulase_N, 1 hit
Gene3Di1.50.10.10, 1 hit
2.60.120.260, 1 hit
2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR004197 Cellulase_Ig-like
IPR000421 FA58C
IPR008979 Galactose-bd-like_sf
IPR001701 Glyco_hydro_9
IPR033126 Glyco_hydro_9_Asp/Glu_AS
IPR018221 Glyco_hydro_9_His_AS
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR026444 Secre_tail
PfamiView protein in Pfam
PF02927 CelD_N, 1 hit
PF00754 F5_F8_type_C, 1 hit
PF00759 Glyco_hydro_9, 1 hit
SUPFAMiSSF48208 SSF48208, 1 hit
SSF49785 SSF49785, 1 hit
SSF81296 SSF81296, 1 hit
TIGRFAMsiTIGR04183 Por_Secre_tail, 1 hit
PROSITEiView protein in PROSITE
PS50022 FA58C_3, 1 hit
PS00592 GH9_2, 1 hit
PS00698 GH9_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5NJL8_9BACT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5NJL8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 2005
Last sequence update: February 1, 2005
Last modified: May 8, 2019
This is version 63 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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