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Protein

Guanylate kinase

Gene

gmk

Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 17ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciFTUL177416:G1G1C-1686-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:FTT_1470c
OrganismiFrancisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Taxonomic identifieri177416 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
Proteomesi
  • UP000001174 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001705391 – 190Guanylate kinaseAdd BLAST190

Interactioni

Protein-protein interaction databases

STRINGi177416.FTT_1470c

Structurei

3D structure databases

ProteinModelPortaliQ5NEY6
SMRiQ5NEY6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 185Guanylate kinase-likeUniRule annotationAdd BLAST183

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037638
KOiK00942
OMAiAGNYYGT

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5NEY6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNYIFIVSA PSGAGKSSLL KAFLATDIGK DNYAVAISHT TREPRVGEIN
60 70 80 90 100
SREYYFVTVA EFEQLLSQDG FIEYAKVFKN YYGTSKAELD RLLALGKNII
110 120 130 140 150
LEIDWQGAQQ TRAIYGDRAK SIFILPPSLD ELRKRLEKRN TDSKETIDYR
160 170 180 190
MEQAQSEISH ADEYDYLLVN DDFSQSLEQF CKYFEQNIQS
Length:190
Mass (Da):21,857
Last modified:February 1, 2005 - v1
Checksum:iCB628206A5B486F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ749949 Genomic DNA Translation: CAG46103.1
RefSeqiWP_003022313.1, NZ_CP010290.1
YP_170406.1, NC_006570.2

Genome annotation databases

EnsemblBacteriaiCAG46103; CAG46103; FTT_1470c
GeneIDi3192552
KEGGiftu:FTT_1470c

Similar proteinsi

Entry informationi

Entry nameiKGUA_FRATT
AccessioniPrimary (citable) accession number: Q5NEY6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: February 1, 2005
Last modified: March 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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