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Protein
Submitted name:

Sparc protein

Gene

Sparc

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Sparc proteinImported
Gene namesi
Name:SparcImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98373 Sparc

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_501430991318 – 302Sequence analysisAdd BLAST285

Expressioni

Gene expression databases

BgeeiENSMUSG00000018593 Expressed in 324 organ(s), highest expression level in vault of skull

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini93 – 150Kazal-likeInterPro annotationAdd BLAST58

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4004 Eukaryota
ENOG41101WW LUCA
HOVERGENiHBG002746
OrthoDBiEOG091G0CPG

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR003645 Fol_N
IPR015369 Follistatin/Osteonectin_EGF
IPR002350 Kazal_dom
IPR036058 Kazal_dom_sf
IPR001999 Osteonectin_CS
IPR037641 SPARC
IPR019577 SPARC/Testican_Ca-bd-dom
PANTHERiPTHR13866 PTHR13866, 1 hit
PfamiView protein in Pfam
PF09289 FOLN, 1 hit
PF00050 Kazal_1, 1 hit
PF10591 SPARC_Ca_bdg, 1 hit
SMARTiView protein in SMART
SM00274 FOLN, 1 hit
SM00280 KAZAL, 1 hit
SUPFAMiSSF100895 SSF100895, 1 hit
SSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS51465 KAZAL_2, 1 hit
PS00612 OSTEONECTIN_1, 1 hit
PS00613 OSTEONECTIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5NCU5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRAWIFFLLC LAGRALAAPQ QTEVAEEIVE EETVVEETGV PVGANPVQVE
60 70 80 90 100
MGEFEDGAEE TVEEVVADNP CQNHHCKHGK VCELDESNTP MCVCQDPTSC
110 120 130 140 150
PAPIGEFEKV CSNDNKTFDS SCHFFATKCT LEGTKKGHKL HLDYIGPCKY
160 170 180 190 200
IAPCLDSELT EFPLRMRDWL KNVLVTLYER DEGNNLLTEK QKLRVKKIHE
210 220 230 240 250
NEKRLEAGDH PVELLARDFE KNYNMYIFPV HWQFGQLDQH PIDGYLSHTE
260 270 280 290 300
LAPLRAPLIP MEHCTTRFFE TCDLDNDKYI ALEEWAGCFG IKEQDINKDL

VI
Length:302
Mass (Da):34,450
Last modified:February 5, 2008 - v1
Checksum:iA1FF717CA32F0F5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014286 mRNA Translation: BAB29245.1
AK049692 mRNA Translation: BAC33875.1
AK133377 mRNA Translation: BAE21622.1
AK146935 mRNA Translation: BAE27545.1
AK161229 mRNA Translation: BAE36253.1
CT010306 mRNA Translation: CAJ18514.1
RefSeqiNP_001277746.1, NM_001290817.1
NP_033268.1, NM_009242.5
UniGeneiMm.291442

Genome annotation databases

GeneIDi20692
KEGGimmu:20692

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014286 mRNA Translation: BAB29245.1
AK049692 mRNA Translation: BAC33875.1
AK133377 mRNA Translation: BAE21622.1
AK146935 mRNA Translation: BAE27545.1
AK161229 mRNA Translation: BAE36253.1
CT010306 mRNA Translation: CAJ18514.1
RefSeqiNP_001277746.1, NM_001290817.1
NP_033268.1, NM_009242.5
UniGeneiMm.291442

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi20692
KEGGimmu:20692

Organism-specific databases

CTDi6678
MGIiMGI:98373 Sparc

Phylogenomic databases

eggNOGiKOG4004 Eukaryota
ENOG41101WW LUCA
HOVERGENiHBG002746
OrthoDBiEOG091G0CPG

Miscellaneous databases

ChiTaRSiSparc mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000018593 Expressed in 324 organ(s), highest expression level in vault of skull

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR003645 Fol_N
IPR015369 Follistatin/Osteonectin_EGF
IPR002350 Kazal_dom
IPR036058 Kazal_dom_sf
IPR001999 Osteonectin_CS
IPR037641 SPARC
IPR019577 SPARC/Testican_Ca-bd-dom
PANTHERiPTHR13866 PTHR13866, 1 hit
PfamiView protein in Pfam
PF09289 FOLN, 1 hit
PF00050 Kazal_1, 1 hit
PF10591 SPARC_Ca_bdg, 1 hit
SMARTiView protein in SMART
SM00274 FOLN, 1 hit
SM00280 KAZAL, 1 hit
SUPFAMiSSF100895 SSF100895, 1 hit
SSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS51465 KAZAL_2, 1 hit
PS00612 OSTEONECTIN_1, 1 hit
PS00613 OSTEONECTIN_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5NCU5_MOUSE
AccessioniPrimary (citable) accession number: Q5NCU5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: November 7, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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