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Entry version 148 (02 Jun 2021)
Sequence version 1 (01 Feb 2005)
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Protein
Submitted name:

Rap guanine nucleotide exchange factor (GEF) 6

Gene

Rapgef6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGTPase activationARBA annotation, Guanine-nucleotide releasing factorPROSITE-ProRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Rap guanine nucleotide exchange factor (GEF) 6Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rapgef6Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2384761, Rapgef6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5NCJ1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5NCJ1

PeptideAtlas

More...
PeptideAtlasi
Q5NCJ1

PRoteomics IDEntifications database

More...
PRIDEi
Q5NCJ1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
361587

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5NCJ1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5NCJ1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000037533, Expressed in mesenteric lymph node and 292 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5NCJ1, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5NCJ1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5NCJ1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini37 – 100Cyclic nucleotide-bindingInterPro annotationAdd BLAST64
Domaini280 – 380Cyclic nucleotide-bindingInterPro annotationAdd BLAST101
Domaini412 – 526N-terminal Ras-GEFInterPro annotationAdd BLAST115
Domaini530 – 600PDZInterPro annotationAdd BLAST71
Domaini749 – 835Ras-associatingInterPro annotationAdd BLAST87
Domaini860 – 1087Ras-GEFInterPro annotationAdd BLAST228

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 20DisorderedSequence analysisAdd BLAST20
Regioni176 – 250DisorderedSequence analysisAdd BLAST75
Regioni640 – 662DisorderedSequence analysisAdd BLAST23
Regioni1075 – 1100DisorderedSequence analysisAdd BLAST26
Regioni1201 – 1326DisorderedSequence analysisAdd BLAST126
Regioni1470 – 1490DisorderedSequence analysisAdd BLAST21
Regioni1558 – 1609DisorderedSequence analysisAdd BLAST52

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi177 – 210Polar residuesSequence analysisAdd BLAST34
Compositional biasi1075 – 1089Polar residuesSequence analysisAdd BLAST15
Compositional biasi1233 – 1300Polar residuesSequence analysisAdd BLAST68
Compositional biasi1558 – 1583Polar residuesSequence analysisAdd BLAST26

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RAPGEF2 family.ARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158124

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002782_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5NCJ1

Database of Orthologous Groups

More...
OrthoDBi
31139at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5NCJ1

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00038, CAP_ED, 1 hit
cd00155, RasGEF, 1 hit
cd06224, REM, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.840.10, 1 hit
2.30.42.10, 1 hit
2.60.120.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018490, cNMP-bd-like
IPR000595, cNMP-bd_dom
IPR001478, PDZ
IPR036034, PDZ_sf
IPR000159, RA_dom
IPR008937, Ras-like_GEF
IPR000651, Ras-like_Gua-exchang_fac_N
IPR023578, Ras_GEF_dom_sf
IPR001895, RASGEF_cat_dom
IPR036964, RASGEF_cat_dom_sf
IPR014710, RmlC-like_jellyroll
IPR029071, Ubiquitin-like_domsf

The PANTHER Classification System

More...
PANTHERi
PTHR23113, PTHR23113, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00027, cNMP_binding, 1 hit
PF00595, PDZ, 1 hit
PF00788, RA, 1 hit
PF00617, RasGEF, 1 hit
PF00618, RasGEF_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00100, cNMP, 1 hit
SM00228, PDZ, 1 hit
SM00314, RA, 1 hit
SM00147, RasGEF, 1 hit
SM00229, RasGEFN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48366, SSF48366, 1 hit
SSF50156, SSF50156, 1 hit
SSF51206, SSF51206, 2 hits
SSF54236, SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50042, CNMP_BINDING_3, 2 hits
PS50106, PDZ, 1 hit
PS50200, RA, 1 hit
PS50009, RASGEF_CAT, 1 hit
PS50212, RASGEF_NTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

Q5NCJ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNSPVDPGAR QALRKKPPER TPEDLNIIYS YLHGMEILSN LREHQLRLMS
60 70 80 90 100
TRARYERYSG NQMLFCSETI ARCWYILLSG SVLVKDSMVL PPCSFGKQFG
110 120 130 140 150
GKRGCDCLVL EPSEMIVVEN SKDNEDSILQ REIPARQSRR RFRKINYKGE
160 170 180 190 200
RQTIIDGVDI NNYLSLPADL TKMHLTDNPH PQVTHVSSSQ SGCSIASDSG
210 220 230 240 250
SSSLSDIYQA TESEVGDVDL TRLPEGPVDS EDEEEEEEEI DRTDPLQGRD
260 270 280 290 300
LVRECLEKEP ADKTDDDVEQ LLEFMHQLPA FANMTMSVRR ELCSVMVFEV
310 320 330 340 350
VEQAGAVILE DGQELDSWYV ILNGTVEISH PDGKIENLFM GNSFGIVPTL
360 370 380 390 400
DKQHMHGAVR TKVDDCQFVC IAQQDYWRIL NHVEKNTHKV EEEGEIVMVH
410 420 430 440 450
EHRELDRSGT RKGHIVIKAT PERLIMHLIE EHSIVDPTYI EDFLLTYRTF
460 470 480 490 500
LETPLDVGIK LLEWFKIDNL RDKVTRIVLL WVNNHFNDFE GDPAMTQFLE
510 520 530 540 550
EFERNLEDTK MNGHLRLLNI ACAAKAKWRQ VVLQKASRES PLHFCLTGGS
560 570 580 590 600
EKGFGVFVEE VESGSKAADA GLKRGDQVME VNGQNFENIT LAKALEILRN
610 620 630 640 650
NTHLALTVKT NIFVFKELLS RTEQEKSGVP HIPKIAEKKS NRHSIQDVPG
660 670 680 690 700
DMEQAPQEKG NKKIKANTVS GGRNKIRKIL DKTRFSILPP KLFSDGGLSQ
710 720 730 740 750
SQDDSIVGTR HCRHSLAIMP IPGTLSSSSP DLLQPTTSML DFSNPSDIPD
760 770 780 790 800
QVIRVFKADQ QSCYIIISKD TTAKEVVCQA VQEFGLTGAS DTYSLCEVSV
810 820 830 840 850
TPEGVIKQRR LPDQFSKLAD RIQLNGRYYL KNNMETETLC SDEDAQELLK
860 870 880 890 900
ESQLSMLQLS TIEVATQLSM RDFDLFRNIE PTEYIDDLFK LDSKTGNTHL
910 920 930 940 950
KQFEDIVNQE TFWVASEILS ESNQLKRMKI IKHFIKIALH CRECKNFNSM
960 970 980 990 1000
FAIISGLNLA PVARLRGTWE KLPSKYEKHL QDLQDLFDPS RNMAKYRNIL
1010 1020 1030 1040 1050
SSQSMQPPII PLFPVVKKDM TFLHEGNDSK VDGLVNFEKL RMIAKEIRHI
1060 1070 1080 1090 1100
IRMTSANMDP AMMFRQRKKR WRSLGSLSQG STNSNMLDVQ GGAHKKRARR
1110 1120 1130 1140 1150
SSLLNAKKLY EDAQMARKVK QYLSSLDIDT DEEKFQMMSL QWEPAYGTLT
1160 1170 1180 1190 1200
KNLTEKRSAK SSEMSPVPLR SVGQTAKVHL HQPHRVSQVL QVPAVNLHPI
1210 1220 1230 1240 1250
RKKGQAKDHV LSTSLPQKGL GPTEEVSVKK HTEDTISVAS SLHSSPPASP
1260 1270 1280 1290 1300
QNSPRKGYTL TPSSKCDNLS DSSHSEISSR SSIVSNGSVD SMSAAGQDER
1310 1320 1330 1340 1350
CSSHSLAVPE PTGALEKTDH PSGISDHSQL AHGWMLSKPC LIKGVAVSSS
1360 1370 1380 1390 1400
LSSEEMSHEH VVLEAADSGR GSWTSCSSSS HDNFQSLQNQ KSWDFLNSYR
1410 1420 1430 1440 1450
HMHLDDPIAE VEPTDCEPCA CPKGCSRTCG QCKGSLETNQ LRQSWASSSS
1460 1470 1480 1490 1500
LSDTCEPNYG TVKRRVLESA PAEAPDGLEP RDTTDPVYKT VTSSTDKGLI
1510 1520 1530 1540 1550
VYCVTSPKKG DRYREPPPTP PGYLGISLAD LKEGPHPHLK PPDYSVAVQR
1560 1570 1580 1590 1600
SKMMLNSLSR LPPAPPSSHT SAWVPSKIGS QPQRHSHPKL ADVADADSEA

DENEQVSAV
Length:1,609
Mass (Da):180,240
Last modified:February 1, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0B2B677E0442B72C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5NCJ0Q5NCJ0_MOUSE
Rap guanine nucleotide exchange fac...
Rapgef6
1,601Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B2RUJ6B2RUJ6_MOUSE
Rap guanine nucleotide exchange fac...
Rapgef6
1,606Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5NCJ5Q5NCJ5_MOUSE
Rap guanine nucleotide exchange fac...
Rapgef6
1,131Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5NCJ4Q5NCJ4_MOUSE
Rap guanine nucleotide exchange fac...
Rapgef6
1,123Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5NCJ2Q5NCJ2_MOUSE
Rap guanine nucleotide exchange fac...
Rapgef6
544Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F8MPT3A0A5F8MPT3_MOUSE
Rap guanine nucleotide exchange fac...
Rapgef6
1,267Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7ACB1F7ACB1_MOUSE
Rap guanine nucleotide exchange fac...
Rapgef6
111Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2P734A0A1W2P734_MOUSE
Rap guanine nucleotide exchange fac...
Rapgef6
599Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_006532624.1, XM_006532561.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000101206; ENSMUSP00000098766; ENSMUSG00000037533

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
192786

UCSC genome browser

More...
UCSCi
uc007iyc.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_006532624.1, XM_006532561.3

3D structure databases

SMRiQ5NCJ1
ModBaseiSearch...

PTM databases

iPTMnetiQ5NCJ1
PhosphoSitePlusiQ5NCJ1

Proteomic databases

jPOSTiQ5NCJ1
MaxQBiQ5NCJ1
PeptideAtlasiQ5NCJ1
PRIDEiQ5NCJ1
ProteomicsDBi361587

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
192786

Genome annotation databases

EnsembliENSMUST00000101206; ENSMUSP00000098766; ENSMUSG00000037533
GeneIDi192786
UCSCiuc007iyc.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51735
MGIiMGI:2384761, Rapgef6

Phylogenomic databases

GeneTreeiENSGT00940000158124
HOGENOMiCLU_002782_0_1_1
InParanoidiQ5NCJ1
OrthoDBi31139at2759
PhylomeDBiQ5NCJ1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
192786, 1 hit in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Rapgef6, mouse
RNActiQ5NCJ1, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000037533, Expressed in mesenteric lymph node and 292 other tissues
ExpressionAtlasiQ5NCJ1, baseline and differential

Family and domain databases

CDDicd00038, CAP_ED, 1 hit
cd00155, RasGEF, 1 hit
cd06224, REM, 1 hit
Gene3Di1.10.840.10, 1 hit
2.30.42.10, 1 hit
2.60.120.10, 2 hits
InterProiView protein in InterPro
IPR018490, cNMP-bd-like
IPR000595, cNMP-bd_dom
IPR001478, PDZ
IPR036034, PDZ_sf
IPR000159, RA_dom
IPR008937, Ras-like_GEF
IPR000651, Ras-like_Gua-exchang_fac_N
IPR023578, Ras_GEF_dom_sf
IPR001895, RASGEF_cat_dom
IPR036964, RASGEF_cat_dom_sf
IPR014710, RmlC-like_jellyroll
IPR029071, Ubiquitin-like_domsf
PANTHERiPTHR23113, PTHR23113, 1 hit
PfamiView protein in Pfam
PF00027, cNMP_binding, 1 hit
PF00595, PDZ, 1 hit
PF00788, RA, 1 hit
PF00617, RasGEF, 1 hit
PF00618, RasGEF_N, 1 hit
SMARTiView protein in SMART
SM00100, cNMP, 1 hit
SM00228, PDZ, 1 hit
SM00314, RA, 1 hit
SM00147, RasGEF, 1 hit
SM00229, RasGEFN, 1 hit
SUPFAMiSSF48366, SSF48366, 1 hit
SSF50156, SSF50156, 1 hit
SSF51206, SSF51206, 2 hits
SSF54236, SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50042, CNMP_BINDING_3, 2 hits
PS50106, PDZ, 1 hit
PS50200, RA, 1 hit
PS50009, RASGEF_CAT, 1 hit
PS50212, RASGEF_NTER, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5NCJ1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5NCJ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 2005
Last sequence update: February 1, 2005
Last modified: June 2, 2021
This is version 148 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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