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Protein

Trafficking protein particle complex subunit 1

Gene

Trappc1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in vesicular transport from endoplasmic reticulum to Golgi.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processER-Golgi transport, Transport

Enzyme and pathway databases

ReactomeiR-MMU-204005 COPII-mediated vesicle transport
R-MMU-6798695 Neutrophil degranulation
R-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyi

Protein namesi
Recommended name:
Trafficking protein particle complex subunit 1
Gene namesi
Name:Trappc1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1098727 Trappc1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002115631 – 145Trafficking protein particle complex subunit 1Add BLAST145

Proteomic databases

EPDiQ5NCF2
MaxQBiQ5NCF2
PaxDbiQ5NCF2
PRIDEiQ5NCF2

PTM databases

iPTMnetiQ5NCF2
PhosphoSitePlusiQ5NCF2

Expressioni

Gene expression databases

BgeeiENSMUSG00000049299 Expressed in 289 organ(s), highest expression level in membranous labyrinth
CleanExiMM_TRAPPC1
ExpressionAtlasiQ5NCF2 baseline and differential
GenevisibleiQ5NCF2 MM

Interactioni

Subunit structurei

Part of the multisubunit TRAPP (transport protein particle) complex.By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi232834, 2 interactors
IntActiQ5NCF2, 1 interactor
STRINGi10090.ENSMUSP00000099661

Structurei

Secondary structure

1145
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ5NCF2
SMRiQ5NCF2
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5NCF2

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3368 Eukaryota
ENOG4111X41 LUCA
GeneTreeiENSGT00510000047863
HOGENOMiHOG000172118
HOVERGENiHBG056032
InParanoidiQ5NCF2
KOiK20300
OMAiNVLHQIY
TreeFamiTF323681

Family and domain databases

InterProiView protein in InterPro
IPR011012 Longin-like_dom_sf
IPR007233 TRAPPC
PANTHERiPTHR23249 PTHR23249, 1 hit
PfamiView protein in Pfam
PF04099 Sybindin, 1 hit
SMARTiView protein in SMART
SM01399 Sybindin, 1 hit
SUPFAMiSSF64356 SSF64356, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.iShow all

Q5NCF2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTVHNLYLFD RNGVCLHYSE WHRKKQAGIP KEEEYKLMYG MLFSIRSFVS
60 70 80 90 100
KMSPLDMKDG FLSFQTSRYK LHYYETPTGI KVVMNTDLGV GPIRDVLHHI
110 120 130 140
YSALYVEFVV KNPLCPLGQT VQSELFRSRL DSYVRSLPFF SARAG
Length:145
Mass (Da):16,882
Last modified:February 1, 2005 - v1
Checksum:i7C8C9FCC1118CDC7
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B1ASW6B1ASW6_MOUSE
Trafficking protein particle comple...
Trappc1
165Annotation score:
B1ASW5B1ASW5_MOUSE
Trafficking protein particle comple...
Trappc1 mCG_20883
135Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645527 Genomic DNA No translation available.
CCDSiCCDS24889.1
RefSeqiNP_001019377.1, NM_001024206.2
UniGeneiMm.28073

Genome annotation databases

EnsembliENSMUST00000102601; ENSMUSP00000099661; ENSMUSG00000049299
ENSMUST00000102602; ENSMUSP00000099662; ENSMUSG00000049299
GeneIDi245828
KEGGimmu:245828
UCSCiuc007jpq.2 mouse

Similar proteinsi

Entry informationi

Entry nameiTPPC1_MOUSE
AccessioniPrimary (citable) accession number: Q5NCF2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: February 1, 2005
Last modified: September 12, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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