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Entry version 117 (16 Oct 2019)
Sequence version 2 (10 Jul 2007)
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Protein

Transcription termination factor 2

Gene

Ttf2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi572 – 579ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Helicase, Hydrolase
Biological processmRNA processing, mRNA splicing, Transcription, Transcription regulation, Transcription termination
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription termination factor 2 (EC:3.6.4.-)
Alternative name(s):
RNA polymerase II termination factor
Transcription release factor 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ttf2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1921294 Ttf2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus, Spliceosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000743771 – 1138Transcription termination factor 2Add BLAST1138

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei436PhosphoserineBy similarity1
Modified residuei859PhosphoserineBy similarity1
Modified residuei884PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5NC05

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5NC05

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5NC05

PeptideAtlas

More...
PeptideAtlasi
Q5NC05

PRoteomics IDEntifications database

More...
PRIDEi
Q5NC05

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5NC05

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5NC05

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000033222 Expressed in 183 organ(s), highest expression level in bone marrow

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5NC05 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5NC05 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CDC5L. Part of the spliceosome (By similarity).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
216447, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q5NC05, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000076208

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini559 – 762Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST204
Domaini971 – 1133Helicase C-terminalPROSITE-ProRule annotationAdd BLAST163

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi713 – 716DEAH box4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SNF2/RAD54 helicase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1001 Eukaryota
COG0553 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162718

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154708

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5NC05

KEGG Orthology (KO)

More...
KOi
K15173

Identification of Orthologs from Complete Genome Data

More...
OMAi
AVWKITS

Database of Orthologous Groups

More...
OrthoDBi
132523at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5NC05

TreeFam database of animal gene trees

More...
TreeFami
TF316297

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.10810, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002464 DNA/RNA_helicase_DEAH_CS
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
IPR010666 Znf_GRF

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit
PF06839 zf-GRF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00690 DEAH_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5NC05-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDLVKCPEHG DACFLKTGVR DGPNKGKSFY VCRTNTCGFV QATDIPVSHC
60 70 80 90 100
LLHEEFVVEL QGLFLPQDKK EWRLFFRCAR TKAEGKQWCG NVPWRQDPNP
110 120 130 140 150
KELSVTSKPQ QPSESQLHSP SQPRNPFRVL NKNQKTLERK QFVEEGERKT
160 170 180 190 200
ADKKLRENNE QLLDQRKEQK PKSNSRMEKD PSSDLVATRQ SGGDREEQEK
210 220 230 240 250
SKFQPKTKKA EGMASKQGHG EVLQGIPKGP HMSESESRGV PNKPETLREK
260 270 280 290 300
ETQLLVPSVP GQNPESKVQK EGHVSREPLK NGEAPSAQVT QRGLAQGPLQ
310 320 330 340 350
GPSKTWRPVP EAPAAPELCS GMAHHATSSS EDSEDDGVSS RPGSPLLFDS
360 370 380 390 400
TVDSQKKGSL QHSDQSVQRQ MPAASGVSKK GDSSDPAAQR ANLTTQLKQK
410 420 430 440 450
KGTLAAVNIQ ALPDKGEKLL KQIQALEDAL SALALSPEQG TKEKCSAQEP
460 470 480 490 500
EQSNITKAAA APLHLVPPQP LPRPLIQPAS SLGLKAGRQE TPEGASQCSG
510 520 530 540 550
GHMNQHHLYN VWKITSEAID ELHRSLKSCP GETAVAEDPA GLKVPLLLHQ
560 570 580 590 600
KQALAWLLWR ESQKPQGGIL ADDMGLGKTL TMIALILTKK NQQKSKEKER
610 620 630 640 650
SEPVTWLSKN DSSVFTSSGT LIVCPASLIH HWKNEVEKRV TSNRLRIYLY
660 670 680 690 700
HGPNRSRHAK VLSTYDIVIT TYSLLAKEIP TTKQEGEVPG ANLSVEGTSA
710 720 730 740 750
PLLQVVWARI ILDEAHNVKN PRVQTSIAVC KLQAQARWAV TGTPIQNNLL
760 770 780 790 800
DMYSLMKFLR CSPFDEFSLW KSQVDNGSMK GGERLSILTK SLLLRRTKDQ
810 820 830 840 850
LDSTGKPLVA LPARRCQLHR LKLSEDERAV YDIFLARSRS ALQSYLKRQE
860 870 880 890 900
GRGSHHGRSP DNPFSRVAQE FGSSVSQGCP AADSQRPSTV HVLSQLLRLR
910 920 930 940 950
QCCCHLSLLK SALDPTELES EGLVLSLEEQ LSALTLSKVD VSEPSPTVSL
960 970 980 990 1000
NGTCFKAELF DDTRRSTKVS SLLAELEAIQ KGPGSQKSVI VSQWTSMLQV
1010 1020 1030 1040 1050
VALHLKKNRL TYATIDGSVN PKQRMDLVEA FNHSQGPQVM LISLLAGGVG
1060 1070 1080 1090 1100
LNLTGGNHLF LLDMHWNPSL EDQACDRIYR VGQKKDVVIH RFVCEGTVEE
1110 1120 1130
KILQLQEKKK DLAKQVLSGS EGPVTKLTLA DLKILFGI
Length:1,138
Mass (Da):125,530
Last modified:July 10, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEA46A8F37DECCC56
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6RQ10F6RQ10_MOUSE
Transcription termination factor 2
Ttf2
182Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti5K → E in AAH87733 (PubMed:15489334).Curated1
Sequence conflicti100P → R in CAI26225 (PubMed:19468303).Curated1
Sequence conflicti175S → C in CAI26225 (PubMed:19468303).Curated1
Sequence conflicti199E → EE in CAI26225 (PubMed:19468303).Curated1
Sequence conflicti208K → E in AAH87733 (PubMed:15489334).Curated1
Sequence conflicti246T → P in CAI26225 (PubMed:19468303).Curated1
Sequence conflicti290 – 292TQR → AQK in CAI26225 (PubMed:19468303).Curated3
Sequence conflicti317E → G in CAI26225 (PubMed:19468303).Curated1
Sequence conflicti355Q → K in CAI26225 (PubMed:19468303).Curated1
Sequence conflicti437 – 438PE → SD in CAI26225 (PubMed:19468303).Curated2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL669872 Genomic DNA Translation: CAM22070.1
AL669937 Genomic DNA Translation: CAI26225.2
BC087733 mRNA Translation: AAH87733.1
BC096625 mRNA Translation: AAH96625.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS17679.1

NCBI Reference Sequences

More...
RefSeqi
NP_001013044.2, NM_001013026.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000076941; ENSMUSP00000076208; ENSMUSG00000033222

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
74044

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:74044

UCSC genome browser

More...
UCSCi
uc008qrb.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL669872 Genomic DNA Translation: CAM22070.1
AL669937 Genomic DNA Translation: CAI26225.2
BC087733 mRNA Translation: AAH87733.1
BC096625 mRNA Translation: AAH96625.1
CCDSiCCDS17679.1
RefSeqiNP_001013044.2, NM_001013026.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi216447, 1 interactor
IntActiQ5NC05, 1 interactor
STRINGi10090.ENSMUSP00000076208

PTM databases

iPTMnetiQ5NC05
PhosphoSitePlusiQ5NC05

Proteomic databases

EPDiQ5NC05
MaxQBiQ5NC05
PaxDbiQ5NC05
PeptideAtlasiQ5NC05
PRIDEiQ5NC05

Genome annotation databases

EnsembliENSMUST00000076941; ENSMUSP00000076208; ENSMUSG00000033222
GeneIDi74044
KEGGimmu:74044
UCSCiuc008qrb.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8458
MGIiMGI:1921294 Ttf2

Phylogenomic databases

eggNOGiKOG1001 Eukaryota
COG0553 LUCA
GeneTreeiENSGT00940000162718
HOGENOMiHOG000154708
InParanoidiQ5NC05
KOiK15173
OMAiAVWKITS
OrthoDBi132523at2759
PhylomeDBiQ5NC05
TreeFamiTF316297

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ttf2 mouse

Protein Ontology

More...
PROi
PR:Q5NC05

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000033222 Expressed in 183 organ(s), highest expression level in bone marrow
ExpressionAtlasiQ5NC05 baseline and differential
GenevisibleiQ5NC05 MM

Family and domain databases

Gene3Di3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR002464 DNA/RNA_helicase_DEAH_CS
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
IPR010666 Znf_GRF
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit
PF06839 zf-GRF, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00690 DEAH_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTTF2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5NC05
Secondary accession number(s): Q4V9Y7, Q5M924
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: July 10, 2007
Last modified: October 16, 2019
This is version 117 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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