Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sperm protein associated with the nucleus on the X chromosome N3

Gene

SPANXN3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Sperm protein associated with the nucleus on the X chromosome N3
Alternative name(s):
Nuclear-associated protein SPAN-Xn3
Short name:
SPANX-N3
SPANX family member N3
Gene namesi
Name:SPANXN3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000189252.4
HGNCiHGNC:33176 SPANXN3
MIMi300666 gene
neXtProtiNX_Q5MJ09

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162404385

Polymorphism and mutation databases

BioMutaiSPANXN3
DMDMi74743051

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002855401 – 141Sperm protein associated with the nucleus on the X chromosome N3Add BLAST141

Proteomic databases

PaxDbiQ5MJ09
PeptideAtlasiQ5MJ09
PRIDEiQ5MJ09
ProteomicsDBi63581

PTM databases

iPTMnetiQ5MJ09
PhosphoSitePlusiQ5MJ09

Expressioni

Gene expression databases

BgeeiENSG00000189252 Expressed in 24 organ(s), highest expression level in testis
CleanExiHS_SPANXN3

Organism-specific databases

HPAiHPA045652

Interactioni

Protein-protein interaction databases

BioGridi126541, 11 interactors
IntActiQ5MJ09, 15 interactors
STRINGi9606.ENSP00000359534

Structurei

3D structure databases

ProteinModelPortaliQ5MJ09
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SPAN-X family.Curated

Phylogenomic databases

eggNOGiENOG410JMMV Eukaryota
ENOG41115AG LUCA
HOGENOMiHOG000015252
HOVERGENiHBG097736
InParanoidiQ5MJ09
OrthoDBiEOG091G0PSU
PhylomeDBiQ5MJ09
TreeFamiTF341404

Family and domain databases

InterProiView protein in InterPro
IPR010007 SPAN-X_fam
PANTHERiPTHR23425 PTHR23425, 1 hit
PfamiView protein in Pfam
PF07458 SPAN-X, 1 hit

Sequencei

Sequence statusi: Complete.

Q5MJ09-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEQPTSSTNG EKTKSPCESN NKKNDEMQEV PNRVLAPEQS LKKTKTSEYP
60 70 80 90 100
IIFVYYLRKG KKINSNQLEN EQSQENSINP IQKEEDEGVD LSEGSSNEDE
110 120 130 140
DLGPCEGPSK EDKDLDSSEG SSQEDEDLGL SEGSSQDSGE D
Length:141
Mass (Da):15,595
Last modified:February 1, 2005 - v1
Checksum:i036B1450B93000C4
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03202643K → N1 PublicationCorresponds to variant dbSNP:rs6654212Ensembl.1
Natural variantiVAR_05368489V → I. Corresponds to variant dbSNP:rs5953851Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY825031 Genomic DNA Translation: AAV97587.1
DQ336128 mRNA Translation: ABC61879.1
DQ336129 mRNA Translation: ABC61880.1
AL030997, AL080239 Genomic DNA Translation: CAI42274.1
AL080239, AL030997 Genomic DNA Translation: CAI41648.1
BC062750 mRNA Translation: AAH62750.1
CCDSiCCDS35418.1
RefSeqiNP_001009609.2, NM_001009609.3
UniGeneiHs.447320

Genome annotation databases

EnsembliENST00000370503; ENSP00000359534; ENSG00000189252
GeneIDi139067
KEGGihsa:139067
UCSCiuc004fbw.4 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY825031 Genomic DNA Translation: AAV97587.1
DQ336128 mRNA Translation: ABC61879.1
DQ336129 mRNA Translation: ABC61880.1
AL030997, AL080239 Genomic DNA Translation: CAI42274.1
AL080239, AL030997 Genomic DNA Translation: CAI41648.1
BC062750 mRNA Translation: AAH62750.1
CCDSiCCDS35418.1
RefSeqiNP_001009609.2, NM_001009609.3
UniGeneiHs.447320

3D structure databases

ProteinModelPortaliQ5MJ09
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126541, 11 interactors
IntActiQ5MJ09, 15 interactors
STRINGi9606.ENSP00000359534

PTM databases

iPTMnetiQ5MJ09
PhosphoSitePlusiQ5MJ09

Polymorphism and mutation databases

BioMutaiSPANXN3
DMDMi74743051

Proteomic databases

PaxDbiQ5MJ09
PeptideAtlasiQ5MJ09
PRIDEiQ5MJ09
ProteomicsDBi63581

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000370503; ENSP00000359534; ENSG00000189252
GeneIDi139067
KEGGihsa:139067
UCSCiuc004fbw.4 human

Organism-specific databases

CTDi139067
EuPathDBiHostDB:ENSG00000189252.4
GeneCardsiSPANXN3
HGNCiHGNC:33176 SPANXN3
HPAiHPA045652
MIMi300666 gene
neXtProtiNX_Q5MJ09
PharmGKBiPA162404385
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410JMMV Eukaryota
ENOG41115AG LUCA
HOGENOMiHOG000015252
HOVERGENiHBG097736
InParanoidiQ5MJ09
OrthoDBiEOG091G0PSU
PhylomeDBiQ5MJ09
TreeFamiTF341404

Miscellaneous databases

GenomeRNAii139067
PROiPR:Q5MJ09
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000189252 Expressed in 24 organ(s), highest expression level in testis
CleanExiHS_SPANXN3

Family and domain databases

InterProiView protein in InterPro
IPR010007 SPAN-X_fam
PANTHERiPTHR23425 PTHR23425, 1 hit
PfamiView protein in Pfam
PF07458 SPAN-X, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSPXN3_HUMAN
AccessioniPrimary (citable) accession number: Q5MJ09
Secondary accession number(s): Q0ZNK4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: February 1, 2005
Last modified: September 12, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again