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Entry version 114 (07 Oct 2020)
Sequence version 2 (18 Mar 2008)
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Protein

Coiled-coil domain-containing protein 158

Gene

CCDC158

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q5M9N0

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coiled-coil domain-containing protein 158
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCDC158
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000163749.17

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26374, CCDC158

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5M9N0

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
339965

Open Targets

More...
OpenTargetsi
ENSG00000163749

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164717707

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q5M9N0, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCDC158

Domain mapping of disease mutations (DMDM)

More...
DMDMi
172045891

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003257601 – 1113Coiled-coil domain-containing protein 158Add BLAST1113

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5M9N0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q5M9N0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5M9N0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5M9N0

PeptideAtlas

More...
PeptideAtlasi
Q5M9N0

PRoteomics IDEntifications database

More...
PRIDEi
Q5M9N0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
63568 [Q5M9N0-1]
63569 [Q5M9N0-2]
63570 [Q5M9N0-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5M9N0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5M9N0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000163749, Expressed in sperm and 109 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5M9N0, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000163749, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
130969, 18 interactors

Database of interacting proteins

More...
DIPi
DIP-47314N

Protein interaction database and analysis system

More...
IntActi
Q5M9N0, 12 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000373566

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q5M9N0, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5M9N0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili72 – 183Sequence analysisAdd BLAST112
Coiled coili243 – 833Sequence analysisAdd BLAST591
Coiled coili1061 – 1113Sequence analysisAdd BLAST53

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi25 – 28Poly-Ser4
Compositional biasi948 – 1056Ser-richAdd BLAST109

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1836, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013339

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_009414_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5M9N0

Identification of Orthologs from Complete Genome Data

More...
OMAi
ERDQYSQ

Database of Orthologous Groups

More...
OrthoDBi
197998at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5M9N0

TreeFam database of animal gene trees

More...
TreeFami
TF337019

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031809, CCDC158

The PANTHER Classification System

More...
PANTHERi
PTHR47615, PTHR47615, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15921, CCDC158, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q5M9N0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MESKAWESNN EDLLSSSGVT SNGGSSSSFF VSSIRGTIIE NTSSAGTLTQ
60 70 80 90 100
VPFFPKYEVE LDSPRKIIPS PGKEHFERVL EEYSHQVKDL QRRLNESNEL
110 120 130 140 150
HEKQKFYLRQ SVIDLQTKLQ EMQMERDAMA DIRRRESQSQ EDLRNQLQNT
160 170 180 190 200
VHELEAAKCL KEDMLKDSNT QIEQLRKMML SHEGVLQEIR SILVDFEEAS
210 220 230 240 250
GKKICEHDSM STLHFRSLGS AISKILRELD TEISYLKGRI FPVEDQLEAL
260 270 280 290 300
KSESQNKIEL LLQQHQDRIE QLISEHEVEI TGLTEKASSA RSQANSIQSQ
310 320 330 340 350
MEIIQEQARN QNSMYMRQLS DLESTVSQLR SELREAKRMY EDKTEELEKQ
360 370 380 390 400
LVLANSELTE ARTERDQFSQ ESGNLDDQLQ KLLADLHKRE KELSLEKEQN
410 420 430 440 450
KRLWDRDTGN SITIDHLRRE LDNRNMEVQR LEALLKALKS ECQGQMERQM
460 470 480 490 500
AAIQGKNESL EKVSSLTAQL ESTKEMLRKV VEELTAKKMT LESSERTISD
510 520 530 540 550
LTTSLQEKER AIEATNAEIT KLRSRVDLKL QELQHLKNEG DHLRNVQTEC
560 570 580 590 600
EALKLQMTEK DKVIEILRQQ IENMTQLVGQ HGRTAGAMQV EKAQLEKEIN
610 620 630 640 650
DRRMELKELK ILKDKKDAKI RELEARVSDL ELEKVKLVNA GSERLRAVKD
660 670 680 690 700
IKQERDQLLN EVKTSRSELN NLSEEYEVLK RNFRNKSEEM EMTTNKLKMQ
710 720 730 740 750
LKSAQSELEQ TRNTLKSMEG SDGHAMKVAM GMQKQITAKR GQIDALQSKI
760 770 780 790 800
QFLEEAMTNA NKEKHFLKEE KSKLSQELST VATEKNKMAG ELEVLRSQER
810 820 830 840 850
RLKEKVTNME VALDKASLQF AECQDIIQRQ EQESVRLKLQ HTLDIKELQG
860 870 880 890 900
PGYTSNSSLK PRLLQPASVT RSHSNVPSSQ STASFLSHHS TKANTLKEDP
910 920 930 940 950
TRDLKQLLQE LRSVINEEPA VSLSKTEEDG RTSLGALEDR VRDCITESSL
960 970 980 990 1000
RSDMCHRSNN SLRDSTEGSK SSETLSREPV TLHAGDREDP SGCFTFTSAA
1010 1020 1030 1040 1050
SPSVKNSASR SFNSSPKKSP VHSLLTSSVE GSIGSTSQYR SAKPIHSSDS
1060 1070 1080 1090 1100
VKDSQSPPIE TTGKTCRKLQ NRLESLQTLV EDLQLKNQAM SSMIRNQEKR
1110
IQKVKDQEKM LLK
Length:1,113
Mass (Da):127,140
Last modified:March 18, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD56CE9B93AFAF24D
GO
Isoform 2 (identifier: Q5M9N0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     368-947: Missing.

Show »
Length:533
Mass (Da):60,601
Checksum:i37E4E416B8056A36
GO
Isoform 3 (identifier: Q5M9N0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     344-406: TEELEKQLVL...KEQNKRLWDR → ENLQNSPLRI...AEFCIKKVMI
     407-1113: Missing.

Show »
Length:406
Mass (Da):46,948
Checksum:iC77829BF0BDB9072
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC05347 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC05359 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BC035224 differs from that shown. Reason: Frameshift.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_039909232E → D. Corresponds to variant dbSNP:rs17001889Ensembl.1
Natural variantiVAR_039910297I → V. Corresponds to variant dbSNP:rs17001885Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_032390344 – 406TEELE…RLWDR → ENLQNSPLRIWTSRSCHYWL CRFGFTLNFRFLTTKISPDV DSAFIFTTLKAVGAEFCIKK VMI in isoform 3. 1 PublicationAdd BLAST63
Alternative sequenceiVSP_032391368 – 947Missing in isoform 2. 1 PublicationAdd BLAST580
Alternative sequenceiVSP_032392407 – 1113Missing in isoform 3. 1 PublicationAdd BLAST707

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC034139 Genomic DNA No translation available.
AC096743 Genomic DNA No translation available.
BC035224 mRNA No translation available.
BC086869 mRNA Translation: AAH86869.1
AK098600 mRNA Translation: BAC05347.1 Different initiation.
AK098636 mRNA Translation: BAC05359.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS43242.1 [Q5M9N0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001036249.1, NM_001042784.1 [Q5M9N0-1]
XP_005263031.1, XM_005262974.4 [Q5M9N0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000388914; ENSP00000373566; ENSG00000163749 [Q5M9N0-1]
ENST00000434846; ENSP00000401742; ENSG00000163749 [Q5M9N0-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
339965

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:339965

UCSC genome browser

More...
UCSCi
uc003hkb.5, human [Q5M9N0-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC034139 Genomic DNA No translation available.
AC096743 Genomic DNA No translation available.
BC035224 mRNA No translation available.
BC086869 mRNA Translation: AAH86869.1
AK098600 mRNA Translation: BAC05347.1 Different initiation.
AK098636 mRNA Translation: BAC05359.1 Different initiation.
CCDSiCCDS43242.1 [Q5M9N0-1]
RefSeqiNP_001036249.1, NM_001042784.1 [Q5M9N0-1]
XP_005263031.1, XM_005262974.4 [Q5M9N0-1]

3D structure databases

SMRiQ5M9N0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi130969, 18 interactors
DIPiDIP-47314N
IntActiQ5M9N0, 12 interactors
STRINGi9606.ENSP00000373566

PTM databases

iPTMnetiQ5M9N0
PhosphoSitePlusiQ5M9N0

Polymorphism and mutation databases

BioMutaiCCDC158
DMDMi172045891

Proteomic databases

EPDiQ5M9N0
MassIVEiQ5M9N0
MaxQBiQ5M9N0
PaxDbiQ5M9N0
PeptideAtlasiQ5M9N0
PRIDEiQ5M9N0
ProteomicsDBi63568 [Q5M9N0-1]
63569 [Q5M9N0-2]
63570 [Q5M9N0-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
6349, 72 antibodies

The DNASU plasmid repository

More...
DNASUi
339965

Genome annotation databases

EnsembliENST00000388914; ENSP00000373566; ENSG00000163749 [Q5M9N0-1]
ENST00000434846; ENSP00000401742; ENSG00000163749 [Q5M9N0-3]
GeneIDi339965
KEGGihsa:339965
UCSCiuc003hkb.5, human [Q5M9N0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
339965
DisGeNETi339965
EuPathDBiHostDB:ENSG00000163749.17

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCDC158
HGNCiHGNC:26374, CCDC158
HPAiENSG00000163749, Tissue enriched (testis)
neXtProtiNX_Q5M9N0
OpenTargetsiENSG00000163749
PharmGKBiPA164717707

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1836, Eukaryota
GeneTreeiENSGT00390000013339
HOGENOMiCLU_009414_0_0_1
InParanoidiQ5M9N0
OMAiERDQYSQ
OrthoDBi197998at2759
PhylomeDBiQ5M9N0
TreeFamiTF337019

Enzyme and pathway databases

PathwayCommonsiQ5M9N0

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
339965, 10 hits in 864 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
339965
PharosiQ5M9N0, Tdark

Protein Ontology

More...
PROi
PR:Q5M9N0
RNActiQ5M9N0, protein

Gene expression databases

BgeeiENSG00000163749, Expressed in sperm and 109 other tissues
GenevisibleiQ5M9N0, HS

Family and domain databases

InterProiView protein in InterPro
IPR031809, CCDC158
PANTHERiPTHR47615, PTHR47615, 1 hit
PfamiView protein in Pfam
PF15921, CCDC158, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCD158_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5M9N0
Secondary accession number(s): Q8IYQ1, Q8N7D4, Q8N7E3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: October 7, 2020
This is version 114 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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