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Protein

Probable protein S-acyltransferase 12

Gene

PAT12

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Palmitoyl acyltransferase.By similarity1 Publication

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei141S-palmitoyl cysteine intermediateBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BRENDAi2.3.1.225 399

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein S-acyltransferase 12 (EC:2.3.1.225)
Alternative name(s):
Probable palmitoyltransferase At4g00840
Zinc finger DHHC domain-containing protein At4g00840
Gene namesi
Name:PAT12
Ordered Locus Names:At4g00840
ORF Names:A_TM018A10.8, T18A10.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G00840
TAIRilocus:2134643 AT4G00840

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei14 – 34HelicalSequence analysisAdd BLAST21
Transmembranei49 – 69HelicalSequence analysisAdd BLAST21
Transmembranei155 – 175HelicalSequence analysisAdd BLAST21
Transmembranei198 – 218HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003636011 – 291Probable protein S-acyltransferase 12Add BLAST291

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ5M757

Expressioni

Gene expression databases

ExpressionAtlasiQ5M757 baseline and differential
GenevisibleiQ5M757 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G00840.1

Structurei

3D structure databases

ProteinModelPortaliQ5M757
SMRiQ5M757
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini111 – 161DHHCPROSITE-ProRule annotationAdd BLAST51

Domaini

The DHHC domain is required for palmitoyltransferase activity.By similarity

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1315 Eukaryota
COG5273 LUCA
HOGENOMiHOG000234777
InParanoidiQ5M757
KOiK20028
OMAiGLRCCQR
OrthoDBiEOG09360KT0
PhylomeDBiQ5M757

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit
PROSITEiView protein in PROSITE
PS50216 DHHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q5M757-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLFRFCSGL KVLGYFMILL VVAVVGVSYY AVVVSTWWPI LIRGDHGALS
60 70 80 90 100
ALAALIIFVF HFLLIMLLWS YFTTVFTDPG SVPEHFRREM GGGDSLEAGT
110 120 130 140 150
STDQGAFGSL GYCTKCRNVK PPRCHHCSVC QRCVLKMDHH CVWIVNCVGA
160 170 180 190 200
RNYKFFLLFL FYTFLETMLD VIVLLPSFIE FFSQAIKHSS SPGKLASLVL
210 220 230 240 250
AFVLNFAFVL SLLCFVVMHI SLLSSNTTSV EVHEKNGEVR WKYDLGKKKN
260 270 280 290
FEQVFGKKKA FWLLPLYSKD DIDNITSLEG LEFPTCSDID P
Length:291
Mass (Da):32,866
Last modified:February 1, 2005 - v1
Checksum:i3AF01A5B3FE08378
GO

Sequence cautioni

The sequence AAB62854 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB80893 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF013294 Genomic DNA Translation: AAB62854.1 Sequence problems.
AL161472 Genomic DNA Translation: CAB80893.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE81944.1
BT020391 mRNA Translation: AAV91337.1
BT020511 mRNA Translation: AAW39012.1
AK229293 mRNA Translation: BAF01156.1
PIRiT01562
RefSeqiNP_567193.2, NM_116310.5
UniGeneiAt.24279
At.71106

Genome annotation databases

EnsemblPlantsiAT4G00840.1; AT4G00840.1; AT4G00840
GeneIDi826193
GrameneiAT4G00840.1; AT4G00840.1; AT4G00840
KEGGiath:AT4G00840

Similar proteinsi

Entry informationi

Entry nameiZDH15_ARATH
AccessioniPrimary (citable) accession number: Q5M757
Secondary accession number(s): O23092
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: February 1, 2005
Last modified: April 25, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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