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Protein

Ferrous iron transport protein B

Gene

feoB

Organism
Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable transporter of a GTP-driven Fe2+ uptake system.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi126MagnesiumCombined sources1
Metal bindingi128MagnesiumCombined sources1
Metal bindingi211MagnesiumCombined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processIon transport, Iron transportUniRule annotation, Transport
LigandGTP-bindingUniRule annotation, Iron, MagnesiumCombined sources, Metal-bindingCombined sources, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ferrous iron transport protein BUniRule annotation
Gene namesi
Name:feoBImported
Ordered Locus Names:stu0608Imported
OrganismiStreptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)Imported
Taxonomic identifieri264199 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000001170 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei281 – 299HelicalUniRule annotationAdd BLAST19
Transmembranei344 – 368HelicalUniRule annotationAdd BLAST25
Transmembranei453 – 473HelicalUniRule annotationAdd BLAST21
Transmembranei512 – 531HelicalUniRule annotationAdd BLAST20
Transmembranei609 – 631HelicalUniRule annotationAdd BLAST23
Transmembranei638 – 660HelicalUniRule annotationAdd BLAST23
Transmembranei672 – 691HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi264199.stu0608

Structurei

3D structure databases

ProteinModelPortaliQ5M586
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5M586

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 162FeoB-type GInterPro annotationAdd BLAST162

Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG4105CE1 Bacteria
COG0370 LUCA
HOGENOMiHOG000054021
KOiK04759
OMAiMEMPDYE

Family and domain databases

CDDicd01879 FeoB, 1 hit
InterProiView protein in InterPro
IPR003373 Fe2_transport_prot-B
IPR011640 Fe2_transport_prot_B_C
IPR030389 G_FEOB_dom
IPR011642 Gate_dom
IPR006073 GTP_binding_domain
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF07664 FeoB_C, 1 hit
PF02421 FeoB_N, 1 hit
PF07670 Gate, 2 hits
PRINTSiPR00326 GTP1OBG
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00437 feoB, 1 hit
PROSITEiView protein in PROSITE
PS51711 G_FEOB, 1 hit

Sequencei

Sequence statusi: Complete.

Q5M586-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEIALIGNP NSGKTSLFNL ITGHNQRVGN WPGVTVERKS GLVKKNKDLE
60 70 80 90 100
IQDLPGIYSM SPYSPEEKVA RDYLLSQRAD SILNVVDATN LERNLYLTTQ
110 120 130 140 150
LIETGIPVTI ALNMIDVLDG QGKKINVDKL SYHLGVPVVA TSALKQTGVD
160 170 180 190 200
QVVKKAAHTT TSTVGDLAFP IYDDRLEAAI SQILEVLGNS VPQRSARFYA
210 220 230 240 250
IKLFEQDSLV EAELDLSQFQ RKEIEDIIRI TEEIFTEDAE SIVINERYAF
260 270 280 290 300
IERVCQMAES HTEDFALTLS DKIDRIVTNR ILALPIFSVV MYLVYFLSIQ
310 320 330 340 350
TVGTMWTDWA NDVLFGKYVP DLVSSGLDYL QVQDWLKSLI VDGIVAGIGT
360 370 380 390 400
VLGFLPQIFV LFICLGVLED IGYMSRIAFV MDRIFRRFGL SGKSFIPMLI
410 420 430 440 450
STGCGVPAVM SSRTIENERD RRITIMTATF MPCSAKLEII ALIAGAFFPG
460 470 480 490 500
NSFVAPSTYF IGIATIILSG IALKKTSFLG GLTSPFIMEL PAYHWPKVLS
510 520 530 540 550
VLRYAFGKAM SFVKRAGTII FSLTVLIWFM SNYNFMLQNV DTEVSILATL
560 570 580 590 600
GKGLSWIFEP LGFGNWQATV AALAGLAAKE TVVATFGILY HNSSEAGLAT
610 620 630 640 650
ALQADYSALA AYSFLIFNLL CAPCFAAIGA IKREMANLRW TVGAIGFQTG
660 670 680 690 700
LAYCVSLILY QFGQVLLYGN PISLWTLVAV LFLVTMIYFV VRKPRQIKDK
710
IITLENLQEA NS
Length:712
Mass (Da):78,700
Last modified:February 1, 2005 - v1
Checksum:iD54840A567688ECF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000023 Genomic DNA Translation: AAV60314.1
RefSeqiWP_002946712.1, NC_006448.1

Genome annotation databases

EnsemblBacteriaiAAV60314; AAV60314; stu0608
KEGGistl:stu0608
PATRICifig|264199.4.peg.616

Entry informationi

Entry nameiQ5M586_STRT2
AccessioniPrimary (citable) accession number: Q5M586
Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 2005
Last sequence update: February 1, 2005
Last modified: July 18, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

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