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Protein

Beta-galactosidase

Gene

BF9343_0156

Organism
Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotationSAAS annotationImported, Hydrolase

Protein family/group databases

CAZyiGH2 Glycoside Hydrolase Family 2

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseUniRule annotationSAAS annotation (EC:3.2.1.23UniRule annotationSAAS annotation)
Alternative name(s):
LactaseUniRule annotation
Gene namesi
ORF Names:BF9343_0156Imported
OrganismiBacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)Imported
Taxonomic identifieri272559 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000006731 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500425916420 – 1034Beta-galactosidaseSequence analysisAdd BLAST1015

Interactioni

Protein-protein interaction databases

STRINGi272559.BF0157

Structurei

3D structure databases

ProteinModelPortaliQ5LIU1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini751 – 1026Bgal_small_NInterPro annotationAdd BLAST276

Sequence similaritiesi

Belongs to the glycosyl hydrolase 2 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4105CNT Bacteria
COG3250 LUCA
HOGENOMiHOG000252444
KOiK01190
OMAiWCDHGIL

Family and domain databases

Gene3Di2.60.120.260, 1 hit
2.60.40.10, 2 hits
2.70.98.10, 1 hit
InterProiView protein in InterPro
IPR004199 B-gal_small/dom_5
IPR036156 Beta-gal/glucu_dom_sf
IPR011013 Gal_mutarotase_sf_dom
IPR008979 Galactose-bd-like_sf
IPR014718 GH-type_carb-bd
IPR006101 Glyco_hydro_2
IPR006103 Glyco_hydro_2_cat
IPR023230 Glyco_hydro_2_CS
IPR006102 Glyco_hydro_2_Ig-like
IPR006104 Glyco_hydro_2_N
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR032312 LacZ_4
PfamiView protein in Pfam
PF02929 Bgal_small_N, 1 hit
PF16353 DUF4981, 1 hit
PF00703 Glyco_hydro_2, 1 hit
PF02836 Glyco_hydro_2_C, 1 hit
PF02837 Glyco_hydro_2_N, 1 hit
PRINTSiPR00132 GLHYDRLASE2
SMARTiView protein in SMART
SM01038 Bgal_small_N, 1 hit
SUPFAMiSSF49303 SSF49303, 2 hits
SSF49785 SSF49785, 1 hit
SSF51445 SSF51445, 1 hit
SSF74650 SSF74650, 1 hit
PROSITEiView protein in PROSITE
PS00719 GLYCOSYL_HYDROL_F2_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q5LIU1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKRQLLTCCL AMCSLATMAQ HDEWKNPEIN AVNRAPMHTN YFAYSSSEEA
60 70 80 90 100
AKADKENSSN FMTLNGIWKF NWVKNADARP TDFYRTDYND KGWGQMKVPG
110 120 130 140 150
VWEMNGYGDP IYVNVGYAWR SQYKNNPPYV PIENNHVGSY RKEIIIPAEW
160 170 180 190 200
SGKEIFAHFG SVTSNMYLWV NGKYVGYSED SKLEAEFNLT KYLKPGKNLI
210 220 230 240 250
AFQVFRWCDG TYLEDQDFFR YSGVGRNCYL YSRNKKYIQD IRVTPDLDSN
260 270 280 290 300
YTNGTLNVAL NLNGSGTVEL NLTDPAGKSV ATAQVNGNGQ KSVVMDVSNP
310 320 330 340 350
EKWTAETPNL YTLTATLKNG SNTLEVIPVK VGFRKIELKG GQILVNGQPV
360 370 380 390 400
LFKGADRHEM DPDGGYVVSR ERMLQDILRM KQLNINAVRT CHYPDDNLWY
410 420 430 440 450
DLCDQYGIYV VAEANIESHG MGYGKETLAK NPSYKKAHME RNQRNVQRGY
460 470 480 490 500
NHPSIIFWSL GNEAGYGPNF EQCYTWIKNE DKTRAVQYEQ AGTNEFTDIF
510 520 530 540 550
CPMYYDYDAC KKYSEGNIDK PLIQCEYAHA MGNSQGGFKE YWDLIRKYPK
560 570 580 590 600
YQGGFIWDFV DQSNHWKNKD GIDIYGYGGD FNKYDASDNN FNDNGLISPD
610 620 630 640 650
RRPNPHAHEV GYFYQSIWTT PGDLSKGEIK VYNENFFRDL SAYYMEWQLL
660 670 680 690 700
ANGEVMQTGV VQDLNVAPQQ TATLKLNLNT EKICPCKELL LNVTYKLKAA
710 720 730 740 750
ETLMPAGSTV AYDQLTIRPY TAKALELKNQ KASNLDIVVP VIKDNDHNYL
760 770 780 790 800
IVEGENFIIE FNKHNGYLSR YEADGMQLLN PGAQLTPNFW RAPTDNDYGA
810 820 830 840 850
GLQHRYAVWK NPGLKLTSLK QSIENEQAIV QAEYEMKAVK GKLFLTYVIN
860 870 880 890 900
NEGAVKVTQK MEAGKEEKVS DMFRFGMQMQ MPENFNEVEY YGRGPVENYA
910 920 930 940 950
DRNHSTLIGK YRQTVAEQFY PYIRPQETGT KTDLRWWRVL NISGNGLQFV
960 970 980 990 1000
GDAPFSASAL NYSIESLDDG VQKDQRHSPE VAKAPFTNLC IDKVQMGLGC
1010 1020 1030
VNSWGTLPLE KYRVPYQDYE FSFILTPVRH KVNM
Length:1,034
Mass (Da):118,260
Last modified:June 21, 2005 - v1
Checksum:i21745560FE083C1B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR626927 Genomic DNA Translation: CAH05935.1
RefSeqiWP_008657952.1, NC_003228.3

Genome annotation databases

EnsemblBacteriaiCAH05935; CAH05935; BF9343_0156
KEGGibfs:BF9343_0156

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR626927 Genomic DNA Translation: CAH05935.1
RefSeqiWP_008657952.1, NC_003228.3

3D structure databases

ProteinModelPortaliQ5LIU1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272559.BF0157

Protein family/group databases

CAZyiGH2 Glycoside Hydrolase Family 2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAH05935; CAH05935; BF9343_0156
KEGGibfs:BF9343_0156

Phylogenomic databases

eggNOGiENOG4105CNT Bacteria
COG3250 LUCA
HOGENOMiHOG000252444
KOiK01190
OMAiWCDHGIL

Family and domain databases

Gene3Di2.60.120.260, 1 hit
2.60.40.10, 2 hits
2.70.98.10, 1 hit
InterProiView protein in InterPro
IPR004199 B-gal_small/dom_5
IPR036156 Beta-gal/glucu_dom_sf
IPR011013 Gal_mutarotase_sf_dom
IPR008979 Galactose-bd-like_sf
IPR014718 GH-type_carb-bd
IPR006101 Glyco_hydro_2
IPR006103 Glyco_hydro_2_cat
IPR023230 Glyco_hydro_2_CS
IPR006102 Glyco_hydro_2_Ig-like
IPR006104 Glyco_hydro_2_N
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR032312 LacZ_4
PfamiView protein in Pfam
PF02929 Bgal_small_N, 1 hit
PF16353 DUF4981, 1 hit
PF00703 Glyco_hydro_2, 1 hit
PF02836 Glyco_hydro_2_C, 1 hit
PF02837 Glyco_hydro_2_N, 1 hit
PRINTSiPR00132 GLHYDRLASE2
SMARTiView protein in SMART
SM01038 Bgal_small_N, 1 hit
SUPFAMiSSF49303 SSF49303, 2 hits
SSF49785 SSF49785, 1 hit
SSF51445 SSF51445, 1 hit
SSF74650 SSF74650, 1 hit
PROSITEiView protein in PROSITE
PS00719 GLYCOSYL_HYDROL_F2_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5LIU1_BACFN
AccessioniPrimary (citable) accession number: Q5LIU1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 21, 2005
Last sequence update: June 21, 2005
Last modified: February 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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