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UniProtKB - Q5KU39 (VPS41_MOUSE)

Entry version 128 (02 Dec 2020)
Sequence version 1 (15 Feb 2005)
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Protein

Vacuolar protein sorting-associated protein 41 homolog

Gene

Vps41

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. Involved in homotypic vesicle fusions between late endosomes and in heterotypic fusions between late endosomes and lysosomes implicated in degradation of endocytosed cargo. Required for fusion of autophagosomes with lysosomes. May link the HOPS complex to endosomal Rab7 via its association with RILP and to lysosomal membranes via its association with ARL8B, suggesting that these interactions may bring the compartments to close proximity for fusion. Involved in the direct trans-Golgi network to late endosomes transport of lysosomal membrane proteins independently of HOPS. Involved in sorting to the regulated secretory pathway presumably implicating the AP-3 adaptor complex. May play a role in HOPS-independent function in the regulated secretory pathway (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri790 – 838RING-type; atypicalPROSITE-ProRule annotationAdd BLAST49

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAutophagy, Protein transport, Transport
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Vacuolar protein sorting-associated protein 41 homolog
Alternative name(s):
VAM2 homolog
Short name:
mVAM2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Vps41
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1929215, Vps41

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasmic vesicle, Endosome, Golgi apparatus, Lysosome, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002530201 – 853Vacuolar protein sorting-associated protein 41 homologAdd BLAST853

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q5KU39

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q5KU39

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5KU39

PeptideAtlas

More...PeptideAtlasi		Q5KU39

PRoteomics IDEntifications database

More...PRIDEi		Q5KU39

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5KU39

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5KU39

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000041236, Expressed in rostral migratory stream and 306 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5KU39, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the putative homotypic fusion and vacuole protein sorting (HOPS) complex; the core of which composed of the class C Vps proteins VPS11, VPS16, VPS18 and VPS33A, is associated with VPS39 and VPS41.

Interacts with RILP, MON1B.

Interacts with ARL8B (GTP-bound form); involved in recruitment to lysosomes and probably hierarchial assembly of the HOPS complex at lysosomal membranes. In vitro can self-assemble into a lattice. Associates with adaptor protein complex 3 (AP-3) and clathrin:AP-3 complexes (By similarity).

Interacts with STX17; this interaction is increased in the absence of TMEM39A (By similarity).

By similarity

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		229988, 11 interactors

Protein interaction database and analysis system

More...IntActi		Q5KU39, 11 interactors

Molecular INTeraction database

More...MINTi		Q5KU39

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000072729

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5KU39, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5KU39

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati567 – 711CHCRAdd BLAST145

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 539Interaction with ARL8BBy similarityAdd BLAST539

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the VPS41 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri790 – 838RING-type; atypicalPROSITE-ProRule annotationAdd BLAST49

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2066, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000000481

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_001285_2_2_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5KU39

Identification of Orthologs from Complete Genome Data

More...OMAi		RCSLGLI

Database of Orthologous Groups

More...OrthoDBi		722805at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5KU39

TreeFam database of animal gene trees

More...TreeFami		TF300451

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.10, 1 hit
2.130.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000547, Clathrin_H-chain/VPS_repeat
IPR011990, TPR-like_helical_dom_sf
IPR016902, VPS41
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR036322, WD40_repeat_dom_sf
IPR001841, Znf_RING

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00637, Clathrin, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF028921, VPS41, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00299, CLH, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50236, CHCR, 1 hit
PS50089, ZF_RING_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5KU39-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEAEEQETE SLEESTDESE EESEEEPKLK YERLSNGVTE ILQKDAASCM 
        60         70         80         90        100
TVHDKFLALG THYGKVYLLD VQGNITQKFD VSPVKINQIS LDDSGEHMGV 
       110        120        130        140        150
CSEDGKLQVF GLYSGEEFHE TFDCPIKIIA VHPQFVRSSC KQFVTGGKKL 
       160        170        180        190        200
LLFERTWMNR WKSSVLHEGE GNIRSVKWRG HLIAWANNMG VKVFDITSKQ 
       210        220        230        240        250
RISNVPRDDI SLRPDMYPCS LCWKDNVTLI IGWGTSIKIC SVKERHASEM 
       260        270        280        290        300
RDLPSRYVEI VSQFETEFYI SGLAPLCDQL VVLSYVKEVS EKTEREYCAR 
       310        320        330        340        350
PRLDIIQPLP ETCEEISSDA LTVRGFQENE CRDYHLEYSE GESLFYVVSP 
       360        370        380        390        400
RDVVVAKERD QDDHIDWLLE KKKYEEALMA AEISQRNIKR HKILDIGLAY 
       410        420        430        440        450
VNHLVERGEY DMAARKCQKI LGKNASLWEY EVYKFKEIGQ LKAISPYLPR 
       460        470        480        490        500
GDPVLKPLIY EMILHEFLES DYEGFATLIR EWPGDLYNNS VIVQAVRDHL 
       510        520        530        540        550
KKDSQNKTLL KTLAELYTYD KNYGNALEIY LTLRHKDVFQ LIHKHNLFSS 
       560        570        580        590        600
IKDKIVLLMD FDSEKAVDML LDNEDKISIK KVVEELEDRP ELQHVYLHKL 
       610        620        630        640        650
FKRDHHKGQR YHEKQISLYA EYDRPNLLPF LRDSTHCPLE KALEICQQRN 
       660        670        680        690        700
FVEETVYLLS RMGNSRSALK MIMEELHDVD KAIEFAKEQD DGELWEDLIL 
       710        720        730        740        750
YSIDKPPFIT GLLNNIGTHV DPILLIHRIK EGMEIPNLRD SLVKILQDYN 
       760        770        780        790        800
LQILLREGCK KILVADSLSL LKKMHRTQMK GVLVDEENIC ESCLSPILPT 
       810        820        830        840        850
DAAKPFSVVV FHCRHMFHKE CLPMPSMNAP AQYCNICSAK NRGPGSAILE 

MKK
Length:853
Mass (Da):98,602
Last modified:February 15, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA4D54AA7C5D0F2DD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti16T → K in BAE37664 (PubMed:16141072).Curated1
Sequence conflicti190G → C in BAC34707 (PubMed:16141072).Curated1
Sequence conflicti401V → L in AAN73032 (Ref. 2) Curated1
Sequence conflicti427 – 428LW → HR in AAN73032 (Ref. 2) Curated2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB028843 mRNA Translation: BAD88410.1
AF327407 mRNA Translation: AAN73032.1
AK051658 mRNA Translation: BAC34707.1
AK164177 mRNA Translation: BAE37664.1
BC023243 mRNA Translation: AAH23243.1
BC049916 mRNA Translation: AAH49916.1
BC119362 mRNA Translation: AAI19363.1
BC125299 mRNA Translation: AAI25300.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS26257.1

NCBI Reference Sequences

More...RefSeqi		NP_742118.3, NM_172120.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000072961; ENSMUSP00000072729; ENSMUSG00000041236

Database of genes from NCBI RefSeq genomes

More...GeneIDi		218035

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:218035

UCSC genome browser

More...UCSCi		uc007pok.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB028843 mRNA Translation: BAD88410.1
AF327407 mRNA Translation: AAN73032.1
AK051658 mRNA Translation: BAC34707.1
AK164177 mRNA Translation: BAE37664.1
BC023243 mRNA Translation: AAH23243.1
BC049916 mRNA Translation: AAH49916.1
BC119362 mRNA Translation: AAI19363.1
BC125299 mRNA Translation: AAI25300.1
CCDSiCCDS26257.1
RefSeqiNP_742118.3, NM_172120.4

3D structure databases

SMRiQ5KU39
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi229988, 11 interactors
IntActiQ5KU39, 11 interactors
MINTiQ5KU39
STRINGi10090.ENSMUSP00000072729

PTM databases

iPTMnetiQ5KU39
PhosphoSitePlusiQ5KU39

Proteomic databases

EPDiQ5KU39
MaxQBiQ5KU39
PaxDbiQ5KU39
PeptideAtlasiQ5KU39
PRIDEiQ5KU39

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		13056, 121 antibodies

Genome annotation databases

EnsembliENSMUST00000072961; ENSMUSP00000072729; ENSMUSG00000041236
GeneIDi218035
KEGGimmu:218035
UCSCiuc007pok.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		27072
MGIiMGI:1929215, Vps41

Phylogenomic databases

eggNOGiKOG2066, Eukaryota
GeneTreeiENSGT00390000000481
HOGENOMiCLU_001285_2_2_1
InParanoidiQ5KU39
OMAiRCSLGLI
OrthoDBi722805at2759
PhylomeDBiQ5KU39
TreeFamiTF300451

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		218035, 7 hits in 19 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Vps41, mouse

Protein Ontology

More...PROi		PR:Q5KU39
RNActiQ5KU39, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000041236, Expressed in rostral migratory stream and 306 other tissues
GenevisibleiQ5KU39, MM

Family and domain databases

Gene3Di1.25.40.10, 1 hit
2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR000547, Clathrin_H-chain/VPS_repeat
IPR011990, TPR-like_helical_dom_sf
IPR016902, VPS41
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR036322, WD40_repeat_dom_sf
IPR001841, Znf_RING
PfamiView protein in Pfam
PF00637, Clathrin, 1 hit
PIRSFiPIRSF028921, VPS41, 1 hit
SMARTiView protein in SMART
SM00299, CLH, 1 hit
SUPFAMiSSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50236, CHCR, 1 hit
PS50089, ZF_RING_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVPS41_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5KU39
Secondary accession number(s): Q05AE9
, Q3TPS1, Q80V99, Q8BKK6, Q8CG01, Q8CJC3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: February 15, 2005
Last modified: December 2, 2020
This is version 128 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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