Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
The new UniProt website is here! Take me to UniProt BETA

UniProtKB - Q5KTQ9 (CAX1C_ORYSJ)

Entry version 98 (25 May 2022)
Sequence version 1 (15 Feb 2005)
Previous versions | rss
Add a publicationFeedback
Protein

Vacuolar cation/proton exchanger 1c

Gene

CAX1c

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Vacuolar cation/proton exchanger (CAX). Translocates Ca2+ and other metal ions into vacuoles using the proton gradient formed by H+-ATPase and H+-pyrophosphatase.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAntiport, Calcium transport, Ion transport, Transport
LigandCalcium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Vacuolar cation/proton exchanger 1c
Alternative name(s):
Ca(2+)/H(+) exchanger 1c
OsCAX1c
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CAX1c
Ordered Locus Names:Os02g0314300, Os02g0314400, Os02g0314100, LOC_Os02g21009
ORF Names:P0705A04.26
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000059680 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2
  • UP000000763 Componenti: Chromosome 2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 73CytoplasmicSequence analysisAdd BLAST73
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei74 – 94HelicalSequence analysisAdd BLAST21
Topological domaini95 – 101ExtracellularSequence analysis7
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Topological domaini123 – 134CytoplasmicSequence analysisAdd BLAST12
Transmembranei135 – 155HelicalSequence analysisAdd BLAST21
Topological domaini156 – 170ExtracellularSequence analysisAdd BLAST15
Transmembranei171 – 191HelicalSequence analysisAdd BLAST21
Topological domaini192 – 201CytoplasmicSequence analysis10
Transmembranei202 – 222HelicalSequence analysisAdd BLAST21
Topological domaini223 – 239ExtracellularSequence analysisAdd BLAST17
Transmembranei240 – 260HelicalSequence analysisAdd BLAST21
Topological domaini261 – 287CytoplasmicSequence analysisAdd BLAST27
Transmembranei288 – 308HelicalSequence analysisAdd BLAST21
Topological domaini309 – 331ExtracellularSequence analysisAdd BLAST23
Transmembranei332 – 352HelicalSequence analysisAdd BLAST21
Topological domaini353 – 360CytoplasmicSequence analysis8
Transmembranei361 – 381HelicalSequence analysisAdd BLAST21
Topological domaini382 – 385ExtracellularSequence analysis4
Transmembranei386 – 406HelicalSequence analysisAdd BLAST21
Topological domaini407 – 424CytoplasmicSequence analysisAdd BLAST18
Transmembranei425 – 445HelicalSequence analysisAdd BLAST21
Topological domaini446 – 450ExtracellularSequence analysis5

Keywords - Cellular componenti

Membrane, Vacuole

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002094991 – 450Vacuolar cation/proton exchanger 1cAdd BLAST450

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5KTQ9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in leaf blades.1 Publication

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5KTQ9, OS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		4530.OS02T0314300-00

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q5KTQ9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5KTQ9

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni28 – 52DisorderedSequence analysisAdd BLAST25
Regioni143 – 178Cation selectionSequence analysisAdd BLAST36
Regioni339 – 374Cation selectionSequence analysisAdd BLAST36

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/proton exchanger (CAX) subfamily. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1397, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_008721_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5KTQ9

Identification of Orthologs from Complete Genome Data

More...OMAi		SAMVWLI

Database of Orthologous Groups

More...OrthoDBi		727723at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.1420.30, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004713, CaH_exchang
IPR004798, CAX-like
IPR004837, NaCa_Exmemb
IPR044880, NCX_ion-bd_dom_sf

The PANTHER Classification System

More...PANTHERi		PTHR31503, PTHR31503, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01699, Na_Ca_ex, 2 hits

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00378, cax, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5KTQ9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPPESSHHH LLESGLLEVS KAPSAAVAAE EEEKKEAAAW TPSSSSSMTG 
        60         70         80         90        100
RKIKSEASPL LRRLLGGPAA QLQEVLLGTK LYPLFSAVPL AVAAESLRLG 
       110        120        130        140        150
RVWVFAFSLI GLAPLAERVS FLSEHIANTV GPTAGGIMNA TCGNVPELII 
       160        170        180        190        200
ALFALHKNKM EILKWSLLGS ILSNLLLVLG SSLLFGGIVN IGKERPLDKR 
       210        220        230        240        250
QADVSIGLLL LGVLCHIATL VSKYTSSTGD SINSSSVMQL SRSCAIVMLI 
       260        270        280        290        300
AYFGSLMFQL KTHRQIFELE EDSSDSSSSE DDATDKSVIG FASAMVWLIG 
       310        320        330        340        350
MAVVTAMLSS YVVTTIEEAS ESMGIPVRFI SIILLPIVGN AAEHAGAIIF 
       360        370        380        390        400
AFKNKIDISL GITLGSATQI SMLVVPVILI VSWVNAIPMD LDFNLLETGS 
       410        420        430        440        450
LAMAVITTAF TLQDDKWHYL KGLNLVFSYI VIAVCFFVMK ALPTLKKEDD
Length:450
Mass (Da):48,164
Last modified:February 15, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB23DD3F2C72C5734
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD15983 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB112771 mRNA Translation: BAD83661.1
AP004891 Genomic DNA Translation: BAD15983.1 Sequence problems.
AP008208 Genomic DNA Translation: BAH91649.1
AP014958 Genomic DNA Translation: BAS78336.1

NCBI Reference Sequences

More...RefSeqi		XP_015622639.1, XM_015767153.1

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		Os02t0314300-00; Os02t0314300-00; Os02g0314300

Database of genes from NCBI RefSeq genomes

More...GeneIDi		9269067

Gramene; a comparative resource for plants

More...Gramenei		Os02t0314300-00; Os02t0314300-00; Os02g0314300

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		osa:9269067

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB112771 mRNA Translation: BAD83661.1
AP004891 Genomic DNA Translation: BAD15983.1 Sequence problems.
AP008208 Genomic DNA Translation: BAH91649.1
AP014958 Genomic DNA Translation: BAS78336.1
RefSeqiXP_015622639.1, XM_015767153.1

3D structure databases

AlphaFoldDBiQ5KTQ9
SMRiQ5KTQ9
ModBaseiSearch...

Protein-protein interaction databases

STRINGi4530.OS02T0314300-00

Proteomic databases

PaxDbiQ5KTQ9

Genome annotation databases

EnsemblPlantsiOs02t0314300-00; Os02t0314300-00; Os02g0314300
GeneIDi9269067
GrameneiOs02t0314300-00; Os02t0314300-00; Os02g0314300
KEGGiosa:9269067

Phylogenomic databases

eggNOGiKOG1397, Eukaryota
HOGENOMiCLU_008721_2_0_1
InParanoidiQ5KTQ9
OMAiSAMVWLI
OrthoDBi727723at2759

Gene expression databases

GenevisibleiQ5KTQ9, OS

Family and domain databases

Gene3Di1.20.1420.30, 2 hits
InterProiView protein in InterPro
IPR004713, CaH_exchang
IPR004798, CAX-like
IPR004837, NaCa_Exmemb
IPR044880, NCX_ion-bd_dom_sf
PANTHERiPTHR31503, PTHR31503, 1 hit
PfamiView protein in Pfam
PF01699, Na_Ca_ex, 2 hits
TIGRFAMsiTIGR00378, cax, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCAX1C_ORYSJ
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5KTQ9
Secondary accession number(s): A0A0P0VI98, C7IY34, Q6Z6R2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: February 15, 2005
Last modified: May 25, 2022
This is version 98 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again