Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 116 (13 Feb 2019)
Sequence version 3 (20 Feb 2007)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

G-protein coupled receptor-associated sorting protein 1

Gene

GPRASP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2.3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • endosome to lysosome transport Source: UniProtKB
  • G protein-coupled receptor catabolic process Source: UniProtKB

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
G-protein coupled receptor-associated sorting protein 1
Short name:
GASP-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GPRASP1
Synonyms:GASP, KIAA0443
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000198932.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24834 GPRASP1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
300417 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5JY77

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
9737

Open Targets

More...
OpenTargetsi
ENSG00000198932

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134970616

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GPRASP1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
126302546

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002390501 – 1395G-protein coupled receptor-associated sorting protein 1Add BLAST1395

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei297PhosphoserineBy similarity1
Modified residuei631PhosphoserineBy similarity1
Modified residuei899PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5JY77

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5JY77

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5JY77

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5JY77

PeptideAtlas

More...
PeptideAtlasi
Q5JY77

PRoteomics IDEntifications database

More...
PRIDEi
Q5JY77

ProteomicsDB human proteome resource

More...
ProteomicsDBi
63484

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5JY77

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5JY77

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198932 Expressed in 214 organ(s), highest expression level in middle temporal gyrus

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5JY77 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA000161
HPA031061

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with cytoplasmic tails of a variety of G-protein coupled receptors such as D2 dopamine receptor/DRD2 (By similarity), delta opioid receptor/OPRD1, beta-2 adrenergic receptor/ADRB2 and D4 dopamine receptor/DRD4. Interacts with PER1. Interacts with BECN2; the interaction is direct.By similarity4 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115086, 29 interactors

Protein interaction database and analysis system

More...
IntActi
Q5JY77, 22 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000355146

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q5JY77

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni899 – 1395OPRD1-bindingAdd BLAST497

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi506 – 978Glu-richAdd BLAST473

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GPRASP family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIBK Eukaryota
ENOG410XUVQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163396

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231409

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG057167

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5JY77

Identification of Orthologs from Complete Genome Data

More...
OMAi
FGSWFWA

Database of Orthologous Groups

More...
OrthoDBi
860703at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5JY77

TreeFam database of animal gene trees

More...
TreeFami
TF335652

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006911 ARM-rpt_dom
IPR016024 ARM-type_fold

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04826 Arm_2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5JY77-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTGAEIESGA QVKPEKKPGE EVVGGAEIEN DVPLVVRPKV RTQAQIMPGA
60 70 80 90 100
RPKNKSKVMP GASTKVETSA VGGARPKSKA KAIPVSRFKE EAQMWAQPRF
110 120 130 140 150
GAERLSKTER NSQTNIIASP LVSTDSVLVA KTKYLSEDRE LVNTDTESFP
160 170 180 190 200
RRKAHYQAGF QPSFRSKEET NMGSWCCPRP TSKQEASPNS DFKWVDKSVS
210 220 230 240 250
SLFWSGDEVT AKFHPGNRVK DSNRSMHMAN QEANTMSRSQ TNQELYIASS
260 270 280 290 300
SGSEDESVKT PWFWARDKTN TWSGPREDPN SRSRFRSKKE VYVESSSGSE
310 320 330 340 350
HEDHLESWFG AGKEAKFRSK MRAGKEANNR ARHRAKREAC IDFMPGSIDV
360 370 380 390 400
IKKESCFWPE ENANTFSRPM IKKEARARAM TKEEAKTKAR ARAKQEARSE
410 420 430 440 450
EEALIGTWFW ATDESSMADE ASIESSLQVE DESIIGSWFW TEEEASMGTG
460 470 480 490 500
ASSKSRPRTD GERIGDSLFG AREKTSMKTG AEATSESILA ADDEQVIIGS
510 520 530 540 550
WFWAGEEVNQ EAEEETIFGS WFWVIDAASV ESGVGVSCES RTRSEEEEVI
560 570 580 590 600
GPWFWSGEQV DIEAGIGEEA RPGAEEETIF GSWFWAENQT YMDCRAETSC
610 620 630 640 650
DTMQGAEEEE PIIGSWFWTR VEACVEGDVN SKSSLEDKEE AMIPCFGAKE
660 670 680 690 700
EVSMKHGTGV RCRFMAGAEE TNNKSCFWAE KEPCMYPAGG GSWKSRPEEE
710 720 730 740 750
EDIVNSWFWS RKYTKPEAII GSWLWATEES NIDGTGEKAK LLTEEETIIN
760 770 780 790 800
SWFWKEDEAI SEATDREESR PEAEEGDIIG SWFWAGEEDR LEPAAETREE
810 820 830 840 850
DRLAAEKEGI VGSWFGAREE TIRREAGSCS KSSPKAEEEE VIIGSWFWEE
860 870 880 890 900
EASPEAVAGV GFESKPGTEE EEITVGSWFW PEEEASIQAG SQAVEEMESE
910 920 930 940 950
TEEETIFGSW FWDGKEVSEE AGPCCVSKPE DDEEMIVESW FWSRDKAIKE
960 970 980 990 1000
TGTVATCESK PENEEGAIVG SWFEAEDEVD NRTDNGSNCG SRTLADEDEA
1010 1020 1030 1040 1050
IVGSWFWAGD EAHFESNPSP VFRAICRSTC SVEQEPDPSR RPQSWEEVTV
1060 1070 1080 1090 1100
QFKPGPWGRV GFPSISPFRF PKEAASLFCE MFGGKPRNMV LSPEGEDQES
1110 1120 1130 1140 1150
LLQPDQPSPE FPFQYDPSYR SVQEIREHLR AKESTEPESS SCNCIQCELK
1160 1170 1180 1190 1200
IGSEEFEELL LLMEKIRDPF IHEISKIAMG MRSASQFTRD FIRDSGVVSL
1210 1220 1230 1240 1250
IETLLNYPSS RVRTSFLENM IRMAPPYPNL NIIQTYICKV CEETLAYSVD
1260 1270 1280 1290 1300
SPEQLSGIRM IRHLTTTTDY HTLVANYMSG FLSLLATGNA KTRFHVLKML
1310 1320 1330 1340 1350
LNLSENLFMT KELLSAEAVS EFIGLFNREE TNDNIQIVLA IFENIGNNIK
1360 1370 1380 1390
KETVFSDDDF NIEPLISAFH KVEKFAKELQ GKTDNQNDPE GDQEN
Length:1,395
Mass (Da):156,865
Last modified:February 20, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i89733CB9A59BC151
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA23715 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_026579315A → G1 PublicationCorresponds to variant dbSNP:rs17339512Ensembl.1
Natural variantiVAR_049263779I → V. Corresponds to variant dbSNP:rs17292748Ensembl.1
Natural variantiVAR_0492641093P → S. Corresponds to variant dbSNP:rs2235804Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB007903 mRNA Translation: BAA23715.3 Different initiation.
AL035427 Genomic DNA No translation available.
BC114552 mRNA Translation: AAI14553.1
AY044233 mRNA Translation: AAK95578.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS35352.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T00068

NCBI Reference Sequences

More...
RefSeqi
NP_001092880.1, NM_001099410.1
NP_001092881.1, NM_001099411.1
NP_001171656.1, NM_001184727.1
NP_055525.3, NM_014710.4
XP_016885470.1, XM_017029981.1
XP_016885471.1, XM_017029982.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.729265
Hs.731996

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000361600; ENSP00000355146; ENSG00000198932
ENST00000415986; ENSP00000393691; ENSG00000198932
ENST00000444152; ENSP00000409420; ENSG00000198932
ENST00000537097; ENSP00000445683; ENSG00000198932

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9737

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9737

UCSC genome browser

More...
UCSCi
uc004eji.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB007903 mRNA Translation: BAA23715.3 Different initiation.
AL035427 Genomic DNA No translation available.
BC114552 mRNA Translation: AAI14553.1
AY044233 mRNA Translation: AAK95578.1
CCDSiCCDS35352.1
PIRiT00068
RefSeqiNP_001092880.1, NM_001099410.1
NP_001092881.1, NM_001099411.1
NP_001171656.1, NM_001184727.1
NP_055525.3, NM_014710.4
XP_016885470.1, XM_017029981.1
XP_016885471.1, XM_017029982.1
UniGeneiHs.729265
Hs.731996

3D structure databases

ProteinModelPortaliQ5JY77
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115086, 29 interactors
IntActiQ5JY77, 22 interactors
STRINGi9606.ENSP00000355146

PTM databases

iPTMnetiQ5JY77
PhosphoSitePlusiQ5JY77

Polymorphism and mutation databases

BioMutaiGPRASP1
DMDMi126302546

Proteomic databases

EPDiQ5JY77
jPOSTiQ5JY77
MaxQBiQ5JY77
PaxDbiQ5JY77
PeptideAtlasiQ5JY77
PRIDEiQ5JY77
ProteomicsDBi63484

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000361600; ENSP00000355146; ENSG00000198932
ENST00000415986; ENSP00000393691; ENSG00000198932
ENST00000444152; ENSP00000409420; ENSG00000198932
ENST00000537097; ENSP00000445683; ENSG00000198932
GeneIDi9737
KEGGihsa:9737
UCSCiuc004eji.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9737
DisGeNETi9737
EuPathDBiHostDB:ENSG00000198932.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GPRASP1
HGNCiHGNC:24834 GPRASP1
HPAiHPA000161
HPA031061
MIMi300417 gene
neXtProtiNX_Q5JY77
OpenTargetsiENSG00000198932
PharmGKBiPA134970616

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IIBK Eukaryota
ENOG410XUVQ LUCA
GeneTreeiENSGT00940000163396
HOGENOMiHOG000231409
HOVERGENiHBG057167
InParanoidiQ5JY77
OMAiFGSWFWA
OrthoDBi860703at2759
PhylomeDBiQ5JY77
TreeFamiTF335652

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
GPRASP1_(gene)

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
9737

Protein Ontology

More...
PROi
PR:Q5JY77

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000198932 Expressed in 214 organ(s), highest expression level in middle temporal gyrus
GenevisibleiQ5JY77 HS

Family and domain databases

InterProiView protein in InterPro
IPR006911 ARM-rpt_dom
IPR016024 ARM-type_fold
PfamiView protein in Pfam
PF04826 Arm_2, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGASP1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5JY77
Secondary accession number(s): O43168, Q96LA1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: February 20, 2007
Last modified: February 13, 2019
This is version 116 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again