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Protein

Protein dopey-1

Gene

DOP1A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in protein traffic between late Golgi and early endosomes.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • Golgi to endosome transport Source: GO_Central
  • protein transport Source: UniProtKB-KW

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein dopey-1Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DOP1AImported
Synonyms:DOPEY1Imported, KIAA1117
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000083097.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21194 DOP1A

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5JWR5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
23033

Open Targets

More...
OpenTargetsi
ENSG00000083097

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134924787

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
DOPEY1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
156630499

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002979471 – 2465Protein dopey-1Add BLAST2465

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1266PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q5JWR5

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q5JWR5

MaxQB - The MaxQuant DataBase

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MaxQBi
Q5JWR5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5JWR5

PeptideAtlas

More...
PeptideAtlasi
Q5JWR5

PRoteomics IDEntifications database

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PRIDEi
Q5JWR5

ProteomicsDB human proteome resource

More...
ProteomicsDBi
63399

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5JWR5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5JWR5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000083097 Expressed in 217 organ(s), highest expression level in corpus callosum

CleanEx database of gene expression profiles

More...
CleanExi
HS_DOPEY1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5JWR5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5JWR5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA027902
HPA027904

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116672, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000195654

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q5JWR5

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the dopey family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3613 Eukaryota
COG5221 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000016421

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000043862

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG051222

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5JWR5

Database of Orthologous Groups

More...
OrthoDBi
29961at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5JWR5

TreeFam database of animal gene trees

More...
TreeFami
TF316855

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR040314 DOP1
IPR007249 Dopey_N

The PANTHER Classification System

More...
PANTHERi
PTHR14042 PTHR14042, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04118 Dopey_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q5JWR5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNTEELELLS DSKYRNYVAA IDKALKNFEY SSEWADLISA LGKLNKVLQN
60 70 80 90 100
NAKYQVVPKK LTIGKRLAQC LHPALPGGVH RKALETYEII FKIIGPKRLA
110 120 130 140 150
KDLFLYSSGL FPLLANAAMS VKPTLLSLYE IYYLPLGKTL KPGLQGLLTG
160 170 180 190 200
ILPGLEEGSE YYERTNMLLE KVAAAVDQSA FYSALWGSLL TSPAVRLPGI
210 220 230 240 250
TYVLAHLNRK LSMEDQLYII GSDIELMVEA VSTSVQDSSV LVQRSTLDLI
260 270 280 290 300
LFCFPFHMSQ ATRPDMIRIL SAALHVVLRR DMSLNRRLYA WLLGFDNNGA
310 320 330 340 350
IIGPRSTRHS NPEEHATYYF TTFSKELLVQ AMVGILQVNG FGEENTLMQD
360 370 380 390 400
LKPFRILISL LDKPELGPVI LEDVLIEVFR TLYSQCKAEL DLQTEPPFSK
410 420 430 440 450
DHAQLSSKLR ENKKTAELIK TANLLFNSFE PYYMWDYVAR WFEECCRRTL
460 470 480 490 500
HVRLQIGPGD SNDSSELQLT NFCLLVDFLL DIVSLPTRSM RVLCQETYIE
510 520 530 540 550
IQTEHLPQLL LRMISALTSH LQTLHLSELT DSLRLCSKIL SKVQPPLLSA
560 570 580 590 600
STGGVLQFPS GQNNSVKEWE DKKVSSVSHE NPTEVFEDGE NPPSSRSSES
610 620 630 640 650
GFTEFIQYQA DRTDDIDREL SEGQGAAAIP IGSTSSETET ASTVGSEETI
660 670 680 690 700
IQTPSVVTQG TATRSRKTAQ KTAMQCCLEY VQQFLTRLIN LYIIQNNSFS
710 720 730 740 750
QSLATEHQGD LGREQGETSK WDRNSQGDVK EKNISKQKTS KEYLSAFLAA
760 770 780 790 800
CQLFLECSSF PVYIAEGNHT SELRSEKLET DCEHVQPPQW LQTLMNACSQ
810 820 830 840 850
ASDFSVQSVA ISLVMDLVGL TQSVAMVTGE NINSVEPAQP LSPNQGRVAV
860 870 880 890 900
VIRPPLTQGN LRYIAEKTEF FKHVALTLWD QLGDGTPQHH QKSVELFYQL
910 920 930 940 950
HNLVPSSSIC EDVISQQLTH KDKKIRMEAH AKFAVLWHLT RDLHINKSSS
960 970 980 990 1000
FVRSFDRSLF IMLDSLNSLD GSTSSVGQAW LNQVLQRHDI ARVLEPLLLL
1010 1020 1030 1040 1050
LLHPKTQRVS VQRVQAERYW NKSPCYPGEE SDKHFMQNFA CSNVSQVQLI
1060 1070 1080 1090 1100
TSKGNGEKPL TMDEIENFSL TVNPLSDRLS LLSTSSETIP MVVSDFDLPD
1110 1120 1130 1140 1150
QQIEILQSSD SGCSQSSAGD NLSYEVDPET VNAQEDSQMP KESSPDDDVQ
1160 1170 1180 1190 1200
QVVFDLICKV VSGLEVESAS VTSQLEIEAM PPKCSDIDPD EETIKIEDDS
1210 1220 1230 1240 1250
IQQSQNALLS NESSQFLSVS AEGGHECVAN GISRNSSSPC ISGTTHTLHD
1260 1270 1280 1290 1300
SSVASIETKS RQRSHSSIQF SFKEKLSEKV SEKETIVKES GKQPGAKPKV
1310 1320 1330 1340 1350
KLARKKDDDK KKSSNEKLKQ TSVFFSDGLD LENWYSCGEG DISEIESDMG
1360 1370 1380 1390 1400
SPGSRKSPNF NIHPLYQHVL LYLQLYDSSR TLYAFSAIKA ILKTNPIAFV
1410 1420 1430 1440 1450
NAISTTSVNN AYTPQLSLLQ NLLARHRISV MGKDFYSHIP VDSNHNFRSS
1460 1470 1480 1490 1500
MYIEILISLC LYYMRSHYPT HVKVTAQDLI GNRNMQMMSI EILTLLFTEL
1510 1520 1530 1540 1550
AKVIESSAKG FPSFISDMLS KCKVQKVILH CLLSSIFSAQ KWHSEKMAGK
1560 1570 1580 1590 1600
NLVAVEEGFS EDSLINFSED EFDNGSTLQS QLLKVLQRLI VLEHRVMTIP
1610 1620 1630 1640 1650
EENETGFDFV VSDLEHISPH QPMTSLQYLH AQPITCQGMF LCAVIRALHQ
1660 1670 1680 1690 1700
HCACKMHPQW IGLITSTLPY MGKVLQRVVV SVTLQLCRNL DNLIQQYKYE
1710 1720 1730 1740 1750
TGLSDSRPLW MASIIPPDMI LTLLEGITAI IHYCLLDPTT QYHQLLVSVD
1760 1770 1780 1790 1800
QKHLFEARSG ILSILHMIMS SVTLLWSILH QADSSEKMTI AASASLTTIN
1810 1820 1830 1840 1850
LGATKNLRQQ ILELLGPISM NHGVHFMAAI AFVWNERRQN KTTTRTKVIP
1860 1870 1880 1890 1900
AASEEQLLLV ELVRSISVMR AETVIQTVKE VLKQPPAIAK DKKHLSLEVC
1910 1920 1930 1940 1950
MLQFFYAYIQ RIPVPNLVDS WASLLILLKD SIQLSLPAPG QFLILGVLNE
1960 1970 1980 1990 2000
FIMKNPSLEN KKDQRDLQDV THKIVDAIGA IAGSSLEQTT WLRRNLEVKP
2010 2020 2030 2040 2050
SPKIMVDGTN LESDVEDMLS PAMETANITP SVYSVHALTL LSEVLAHLLD
2060 2070 2080 2090 2100
MVFYSDEKER VIPLLVNIMH YVVPYLRNHS AHNAPSYRAC VQLLSSLSGY
2110 2120 2130 2140 2150
QYTRRAWKKE AFDLFMDPSF FQMDASCVNH WRAIMDNLMT HDKTTFRDLM
2160 2170 2180 2190 2200
TRVAVAQSSS LNLFANRDVE LEQRAMLLKR LAFAIFSSEI DQYQKYLPDI
2210 2220 2230 2240 2250
QERLVESLRL PQVPTLHSQV FLFFRVLLLR MSPQHLTSLW PTMITELVQV
2260 2270 2280 2290 2300
FLLMEQELTA DEDISRTSGP SVAGLETTYT GGNGFSTSYN SQRWLNLYLS
2310 2320 2330 2340 2350
ACKFLDLALA LPSENLPQFQ MYRWAFIPEA SDDSGLEVRR QGIHQREFKP
2360 2370 2380 2390 2400
YVVRLAKLLR KRAKKNPEED NSGRTLGWEP GHLLLTICTV RSMEQLLPFF
2410 2420 2430 2440 2450
NVLSQVFNSK VTSRCGGHSG SPILYSNAFP NKDMKLENHK PCSSKARQKI
2460
EEMVEKDFLE GMIKT
Length:2,465
Mass (Da):277,355
Last modified:February 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i97C58882414BAA6E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5TA12Q5TA12_HUMAN
Protein dopey-1
DOP1A
2,476Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R3Y1S4R3Y1_HUMAN
Protein dopey-1
DOP1A
171Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB15631 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_034690596R → Q. Corresponds to variant dbSNP:rs4706980Ensembl.1
Natural variantiVAR_0366071155D → H in a breast cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_0346911781Q → L. Corresponds to variant dbSNP:rs9444039Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL121716 Genomic DNA No translation available.
AL139333 Genomic DNA No translation available.
AB029040 mRNA Translation: BAA83069.2
AL050080 mRNA Translation: CAB43259.1
AL162056 mRNA Translation: CAB82395.1
AK027030 mRNA Translation: BAB15631.1 Different initiation.
BC048342 mRNA Translation: AAH48342.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4996.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T47141

NCBI Reference Sequences

More...
RefSeqi
NP_055833.2, NM_015018.3
XP_016866052.1, XM_017010563.1
XP_016866053.1, XM_017010564.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.520246
Hs.708998

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000349129; ENSP00000195654; ENSG00000083097

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23033

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:23033

UCSC genome browser

More...
UCSCi
uc003pjs.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121716 Genomic DNA No translation available.
AL139333 Genomic DNA No translation available.
AB029040 mRNA Translation: BAA83069.2
AL050080 mRNA Translation: CAB43259.1
AL162056 mRNA Translation: CAB82395.1
AK027030 mRNA Translation: BAB15631.1 Different initiation.
BC048342 mRNA Translation: AAH48342.1
CCDSiCCDS4996.1
PIRiT47141
RefSeqiNP_055833.2, NM_015018.3
XP_016866052.1, XM_017010563.1
XP_016866053.1, XM_017010564.1
UniGeneiHs.520246
Hs.708998

3D structure databases

ProteinModelPortaliQ5JWR5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116672, 3 interactors
STRINGi9606.ENSP00000195654

PTM databases

iPTMnetiQ5JWR5
PhosphoSitePlusiQ5JWR5

Polymorphism and mutation databases

BioMutaiDOPEY1
DMDMi156630499

Proteomic databases

EPDiQ5JWR5
jPOSTiQ5JWR5
MaxQBiQ5JWR5
PaxDbiQ5JWR5
PeptideAtlasiQ5JWR5
PRIDEiQ5JWR5
ProteomicsDBi63399

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000349129; ENSP00000195654; ENSG00000083097
GeneIDi23033
KEGGihsa:23033
UCSCiuc003pjs.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23033
DisGeNETi23033
EuPathDBiHostDB:ENSG00000083097.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
DOPEY1

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0006035
HIX0033209
HGNCiHGNC:21194 DOP1A
HPAiHPA027902
HPA027904
neXtProtiNX_Q5JWR5
OpenTargetsiENSG00000083097
PharmGKBiPA134924787

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3613 Eukaryota
COG5221 LUCA
GeneTreeiENSGT00390000016421
HOGENOMiHOG000043862
HOVERGENiHBG051222
InParanoidiQ5JWR5
OrthoDBi29961at2759
PhylomeDBiQ5JWR5
TreeFamiTF316855

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
DOPEY1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
23033

Protein Ontology

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PROi
PR:Q5JWR5

Gene expression databases

BgeeiENSG00000083097 Expressed in 217 organ(s), highest expression level in corpus callosum
CleanExiHS_DOPEY1
ExpressionAtlasiQ5JWR5 baseline and differential
GenevisibleiQ5JWR5 HS

Family and domain databases

InterProiView protein in InterPro
IPR040314 DOP1
IPR007249 Dopey_N
PANTHERiPTHR14042 PTHR14042, 1 hit
PfamiView protein in Pfam
PF04118 Dopey_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDOP1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5JWR5
Secondary accession number(s): Q86XV1
, Q9H5J5, Q9NSL4, Q9UPN5, Q9Y414
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: February 20, 2007
Last modified: January 16, 2019
This is version 82 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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