UniProtKB - Q5JW30 (Q5JW30_HUMAN)
Protein
Submitted name:
Double-stranded RNA-binding protein Staufen homolog 1
Gene
STAU1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- RNA binding Source: UniProtKB-UniRule
Keywordsi
Molecular function | RNA-bindingPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Double-stranded RNA-binding protein Staufen homolog 1Imported |
Gene namesi | Name:STAU1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000124214.19 |
HGNCi | HGNC:11370, STAU1 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
PTM / Processingi
Proteomic databases
MaxQBi | Q5JW30 |
PeptideAtlasi | Q5JW30 |
PRIDEi | Q5JW30 |
ProteomicsDBi | 63363 |
Expressioni
Gene expression databases
Bgeei | ENSG00000124214, Expressed in oviduct epithelium and 252 other tissues |
ExpressionAtlasi | Q5JW30, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 46 – 81 | DRBMInterPro annotationAdd BLAST | 36 | |
Domaini | 103 – 170 | DRBMInterPro annotationAdd BLAST | 68 | |
Domaini | 203 – 271 | DRBMInterPro annotationAdd BLAST | 69 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 277 – 314 | DisorderedSequence analysisAdd BLAST | 38 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 285 – 299 | PolyampholyteSequence analysisAdd BLAST | 15 |
Phylogenomic databases
GeneTreei | ENSGT00940000157304 |
HOGENOMi | CLU_009602_0_0_1 |
Family and domain databases
CDDi | cd00048, DSRM, 2 hits |
InterProi | View protein in InterPro IPR014720, dsRBD_dom IPR032478, Staufen_C |
Pfami | View protein in Pfam PF00035, dsrm, 3 hits PF16482, Staufen_C, 1 hit |
SMARTi | View protein in SMART SM00358, DSRM, 3 hits |
PROSITEi | View protein in PROSITE PS50137, DS_RBD, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
Q5JW30-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKLGKKPMYK PVDPYSRMQS TYNYNMRGGA YPPRYFYPFP VPPLLYQVEL
60 70 80 90 100
SVGGQQFNGK GKTRQAAKHD AAAKALRILQ NEPLPERLEV NGRESEEENL
110 120 130 140 150
NKSEISQVFE IALKRNLPVN FEVARESGPP HMKNFVTKVS VGEFVGEGEG
160 170 180 190 200
KSKKISKKNA AIAVLEELKK LPPLPAVERV KPRIKKKTKP IVKTSPEYGQ
210 220 230 240 250
GINPISRLAQ IQQAKKEKEP EYTLLTERGL PRRREFVMQV KVGNHTAEGT
260 270 280 290 300
GTNKKVAKRN AAENMLEILG FKVPQAQPTK PALKSEEKTP IKKPGDGRKV
310 320 330 340 350
TFFEPGSGDE NGTSNKEDEF RMPYLSHQQL PAGILPMVPE VAQAVGVSQG
360 370 380 390 400
HHTKDFTRAA PNPAKATVTA MIARELLYGG TSPTAETILK NNISSGHVPH
410 420 430 440 450
GPLTRPSEQL DYLSRVQGFQ VEYKDFPKNN KNEFVSLINC SSQPPLISHG
460 470 480 490
IGKDVESCHD MAALNILKLL SELDQQSTEM PRTGNGPMSV CGRC
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO95793 | STAU1_HUMAN | Double-stranded RNA-binding protein... | STAU1 STAU | 577 | Annotation score: | ||
A0A087X1A5 | A0A087X1A5_HUMAN | Double-stranded RNA-binding protein... | STAU1 | 493 | Annotation score: | ||
Q5JW28 | Q5JW28_HUMAN | Double-stranded RNA-binding protein... | STAU1 | 199 | Annotation score: | ||
F6UDC6 | F6UDC6_HUMAN | Double-stranded RNA-binding protein... | STAU1 | 129 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL133174 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000371792; ENSP00000360857; ENSG00000124214 |
UCSCi | uc061xpn.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL133174 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q5JW30, 1 interactor |
Proteomic databases
MaxQBi | Q5JW30 |
PeptideAtlasi | Q5JW30 |
PRIDEi | Q5JW30 |
ProteomicsDBi | 63363 |
Protocols and materials databases
Antibodypediai | 13554, 387 antibodies |
Genome annotation databases
Ensembli | ENST00000371792; ENSP00000360857; ENSG00000124214 |
UCSCi | uc061xpn.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000124214.19 |
HGNCi | HGNC:11370, STAU1 |
OpenTargetsi | ENSG00000124214 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000157304 |
HOGENOMi | CLU_009602_0_0_1 |
Miscellaneous databases
ChiTaRSi | STAU1, human |
Gene expression databases
Bgeei | ENSG00000124214, Expressed in oviduct epithelium and 252 other tissues |
ExpressionAtlasi | Q5JW30, baseline and differential |
Family and domain databases
CDDi | cd00048, DSRM, 2 hits |
InterProi | View protein in InterPro IPR014720, dsRBD_dom IPR032478, Staufen_C |
Pfami | View protein in Pfam PF00035, dsrm, 3 hits PF16482, Staufen_C, 1 hit |
SMARTi | View protein in SMART SM00358, DSRM, 3 hits |
PROSITEi | View protein in PROSITE PS50137, DS_RBD, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5JW30_HUMAN | |
Accessioni | Q5JW30Primary (citable) accession number: Q5JW30 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 15, 2005 |
Last sequence update: | February 15, 2005 | |
Last modified: | August 12, 2020 | |
This is version 103 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |